All individuals in MeSH

Label Id Description
Cytochrome P-450 CYP2C9 D065729 [A cytochrome P-450 subtype that has specificity for acidic XENOBIOTICS. It oxidizes a broad range of important clinical drugs that fall under the categories of NONSTEROIDAL ANTI-INFLAMMATORY AGENTS; HYPOGLYCEMIC AGENTS; ANTCOAGULANTS; and DIURETICS. ]
Cytochrome P-450 CYP2C9 Inducers D065698 [Drugs and compounds that induce the synthesis of CYTOCHROME P-450 CYP2C9. ]
Cytochrome P-450 CYP2C9 Inhibitors D065688 [Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 CYP2C9. ]
Cytochrome P-450 CYP2D6 D019389 [A cytochrome P450 enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals, such as DEBRISOQUINE; ADRENERGIC RECEPTOR ANTAGONISTS; and TRICYCLIC ANTIDEPRESSANTS. This enzyme is deficient in up to 10 percent of the Caucasian population. ]
Cytochrome P-450 CYP2D6 Inducers D065699 [Drugs and compounds that induce the synthesis of CYTOCHROME P-450 CYP2D6. ]
Cytochrome P-450 CYP2D6 Inhibitors D065690 [Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 CYP2D6. ]
Cytochrome P-450 CYP2E1 D019392 [An ethanol-inducible cytochrome P450 enzyme that metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Substrates include ETHANOL; INHALATION ANESTHETICS; BENZENE; ACETAMINOPHEN and other low molecular weight compounds. CYP2E1 has been used as an enzyme marker in the study of alcohol abuse. ]
Cytochrome P-450 CYP2E1 Inducers D065700 [Drugs and compounds that induce the synthesis of CYTOCHROME P-450 CYP2E1. ]
Cytochrome P-450 CYP2E1 Inhibitors D065691 [Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 CYP2E1. ]
Cytochrome P-450 CYP3A D051544 [A specific subtype of CYP3A. , A cytochrome P-450 suptype that has specificity for a broad variety of lipophilic compounds, including STEROIDS; FATTY ACIDS; and XENOBIOTICS. This enzyme has clinical significance due to its ability to metabolize a diverse array of clinically important drugs such as CYCLOSPORINE; VERAPAMIL; and MIDAZOLAM. This enzyme also catalyzes the N-demethylation of ERYTHROMYCIN. ]
Cytochrome P-450 CYP3A Inducers D065701 [Drugs and compounds that induce the synthesis of CYTOCHROME P-450 CYP3A. ]
Cytochrome P-450 CYP3A Inhibitors D065692 [Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 CYP3A. ]
Cytochrome P-450 CYP4A D042926 [A P450 oxidoreductase that catalyzes the hydroxylation of the terminal carbon of linear hydrocarbons such as OCTANES and FATTY ACIDS in the omega position. The enzyme may also play a role in the oxidation of a variety of structurally unrelated compounds such as XENOBIOTICS, and STEROIDS. ]
Cytochrome P-450 Enzyme Inducers D065693 [Drugs and compounds that induce the synthesis of CYTOCHROME P-450 ENZYMES. ]
Cytochrome P-450 Enzyme Inhibitors D065607 [Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 ENZYMES. ]
Cytochrome P-450 Enzyme System D003577 [A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism. ]
Cytochrome P450 Family 1 D000072461 [A cytochrome P450 enzyme family whose members function primarily in the metabolism of XENOBIOTICS, including drugs and POLYCYCLIC AROMATIC HYDROCARBONS. ]
Cytochrome P450 Family 11 D000072476 [A cytochrome P450 enzyme family whose members localize to the INNER MITOCHONDRIAL MEMBRANE where they function in the biosynthesis of STEROIDS. ]
Cytochrome P450 Family 12 D000072477 [A cytochrome P450 enzyme family that occurs in insects and is expressed in MITOCHONDRIA. ]
Cytochrome P450 Family 17 D000072478 [A cytochrome P450 enzyme family that functions in the biosynthesis of STEROIDS and includes STEROID 17-ALPHA-HYDROXYLASE. ]