All individuals in MeSH

Label Id Description
Cytochalasin B D003571 [A cytotoxic member of the CYTOCHALASINS. ]
Cytochalasin D D015638 [A fungal metabolite that blocks cytoplasmic cleavage by blocking formation of contractile microfilament structures resulting in multinucleated cell formation, reversible inhibition of cell movement, and the induction of cellular extrusion. Additional reported effects include the inhibition of actin polymerization, DNA synthesis, sperm motility, glucose transport, thyroid secretion, and growth hormone release. ]
Cytochalasins D003572 [11- to 14-membered macrocyclic lactones with a fused isoindolone. Members with INDOLES attached at the C10 position are called chaetoglobosins. They are produced by various fungi. Some members interact with ACTIN and inhibit CYTOKINESIS. ]
Cytochrome P-450 CYP11B2 D019405 [A mitochondrial cytochrome P450 enzyme that catalyzes the 18-hydroxylation of steroids in the presence of molecular oxygen and NADPH-specific flavoprotein. This enzyme, encoded by CYP11B2 gene, is important in the conversion of CORTICOSTERONE to 18-hydroxycorticosterone and the subsequent conversion to ALDOSTERONE. ]
Cytochrome P-450 CYP1A1 D019363 [A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity. ]
Cytochrome P-450 CYP1A2 D019388 [A cytochrome P450 enzyme subtype that has specificity for relatively planar heteroaromatic small molecules, such as CAFFEINE and ACETAMINOPHEN. ]
Cytochrome P-450 CYP1A2 Inducers D065694 [Drugs and compounds that induce the synthesis of CYTOCHROME P-450 CYP1A2. ]
Cytochrome P-450 CYP1A2 Inhibitors D065609 [Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 CYP1A2. ]
Cytochrome P-450 CYP1B1 D065633 [A cytochrome P450 aryl hydrocarbon hydroxylase that has specificity for ESTROGENS which it converts into 4-hydroxy estrogens. CYP1B1 has been shown to be physiologically important for FETAL DEVELOPMENT with mutations in the CYP1B1 gene resulting in congenital forms of GLAUCOMA and Peter's anomaly. ]
Cytochrome P-450 CYP2A6 D065637 [A cytochrome P450 enzyme that has specificity for the 7-hydroxylation of coumarin. ]
Cytochrome P-450 CYP2B1 D019362 [A major cytochrome P-450 enzyme which is inducible by PHENOBARBITAL in both the LIVER and SMALL INTESTINE. It is active in the metabolism of compounds like pentoxyresorufin, TESTOSTERONE, and ANDROSTENEDIONE. This enzyme, encoded by CYP2B1 gene, also mediates the activation of CYCLOPHOSPHAMIDE and IFOSFAMIDE to MUTAGENS. ]
Cytochrome P-450 CYP2B6 D065702 [A cytochrome P450 enzyme subtype that oxidizes a diverse array of XENOBIOTICS. The expression of CYP2B6 varies widely between individuals which is due to the high rate of GENETIC POLYMORPHISMS. Examples of drugs metabolized by CYP2B6 include BUPROPION; efavirenz; CYCLOPHOSPHAMIDE; and MEPERIDINE. ]
Cytochrome P-450 CYP2B6 Inducers D065695 [Drugs and compounds that induce the synthesis of CYTOCHROME P-450 CYP2B6. ]
Cytochrome P-450 CYP2B6 Inhibitors D065686 [Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 CYP2B6. ]
Cytochrome P-450 CYP2C19 D065731 [A cytochrome P-450 enzyme subtype that oxidizes several important groups of drugs including many PROTON PUMP INHIBITORS and ANTICONVULSANTS. ]
Cytochrome P-450 CYP2C19 Inducers D065697 [Drugs and compounds that induce the synthesis of CYTOCHROME P-450 CYP2C19. ]
Cytochrome P-450 CYP2C19 Inhibitors D065689 [Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 CYP2C19. ]
Cytochrome P-450 CYP2C8 D065727 [A liver microsomal cytochrome P450 hydroxylase that oxidizes a broad spectrum of substrates including STEROIDS, FATTY ACIDS, and XENOBIOTICS. Examples of pharmaceutical substrates for CYP2C8 include; PACLITAXOL; torsemide; and; AMODIAQUINE ]
Cytochrome P-450 CYP2C8 Inducers D065696 [Drugs and compounds that induce the synthesis of CYTOCHROME P-450 CYP2C8. ]
Cytochrome P-450 CYP2C8 Inhibitors D065687 [Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 CYP2C8. ]