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Clinical Trials, Veterinary as Topic
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D000078665 |
[Works about clinical studies in which animal participants are assigned to receive one or more interventions so that researchers can evaluate the interventions on biomedical or health-related outcomes. The assignments are determined by the study protocol. Animal participants may receive diagnostic, therapeutic, or other types of interventions.
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Clione
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D049852 |
[A genus of small, shell-less, marine mollusks in the family Clione, superorder GASTROPODA. These pteropod (possessing a foot developed into wing-like organ for swimming) sea slugs feed exclusively on another pteropod mollusk, Limacina.
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Clioquinol
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D007464 |
[A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
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Clitoria
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D031292 |
[A plant genus of the family FABACEAE that contains ternatins (anthocyanins) and preternatins, antifungal proteins, stigmast-4-ene-3,6-dione, and clitoriacetal (ROTENONE).
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Clitoris
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D002987 |
[An erectile structure homologous with the penis, situated beneath the anterior labial commissure, partially hidden between the anterior ends of the labia minora.
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Cloaca
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D002988 |
[A dilated cavity extended caudally from the hindgut. In adult birds, reptiles, amphibians, and many fishes but few mammals, cloaca is a common chamber into which the digestive, urinary and reproductive tracts discharge their contents. In most mammals, cloaca gives rise to LARGE INTESTINE; URINARY BLADDER; and GENITALIA.
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Cloacin
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D002989 |
[A bacteriocin produced by a plasmid that can occur in several bacterial strains. It is a basic protein of molecular weight 56,000 and exists in a complex with its immunity protein which protects the host bacterium from its effects.
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Clobazam
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D000078306 |
[A benzodiazepine derivative that is a long-acting GABA-A RECEPTOR agonist. It is used as an antiepileptic in the treatment of SEIZURES, including seizures associated with LENNOX-GASTAUT SYNDROME. It is also used as an anxiolytic, for the short-term treatment of acute ANXIETY.
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Clobetasol
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D002990 |
[This is the form in trademark preparations.
, A derivative of PREDNISOLONE with high glucocorticoid activity and low mineralocorticoid activity. Absorbed through the skin faster than FLUOCINONIDE, it is used topically in treatment of PSORIASIS but may cause marked adrenocortical suppression.
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Clodronic Acid
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D004002 |
[A diphosphonate which affects calcium metabolism. It inhibits bone resorption and soft tissue calcification.
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Clofarabine
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D000077866 |
[An adenine arabinonucleoside derivative that acts as an antineoplastic antimetabolite. It is used in the treatment of ACUTE LYMPHOID LEUKEMIA in pediatric patients who have relapsed.
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Clofazimine
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D002991 |
[A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
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Clofenapate
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D002992 |
[An oral hypolipemic agent primarily used in DOGS and RATS.
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Clofibrate
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D002994 |
[A fibric acid derivative used in the treatment of HYPERLIPOPROTEINEMIA TYPE III and severe HYPERTRIGLYCERIDEMIA. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)
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Clofibric Acid
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D002995 |
[An antilipemic agent that is the biologically active metabolite of CLOFIBRATE.
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Clomiphene
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D002996 |
[A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue. Note that ENCLOMIPHENE and ZUCLOMIPHENE are the (E) and (Z) isomers of Clomiphene respectively.
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Clomipramine
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D002997 |
[A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
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Clonal Anergy
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D017635 |
[Functional inactivation of T- or B-lymphocytes rendering them incapable of eliciting an immune response to antigen. This occurs through different mechanisms in the two kinds of lymphocytes and can contribute to SELF TOLERANCE.
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Clonal Deletion
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D017637 |
[Removal, via CELL DEATH, of immature lymphocytes that interact with antigens during maturation. For T-lymphocytes this occurs in the thymus and ensures that mature T-lymphocytes are self tolerant. B-lymphocytes may also undergo clonal deletion.
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Clonal Evolution
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D060965 |
[The process of accumulation of genetic and epigenetic changes over time in individual cells and the effect of the changes on CELL PROLIFERATION.
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