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Pachyonychia Congenita
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D053549 |
[A group of inherited ectodermal dysplasias whose most prominent clinical feature is hypertrophic nail dystrophy resulting in PACHYONYCHIA. Several specific subtypes of pachyonychia congenita have been associated with mutations in genes that encode KERATINS.
, A subtype of pachyonychia congenita that is associated with mutations in the genes for KERATIN-17 or KERATIN-6B.
, A subtype of pachyonychia congenita that is associated with mutations in the gene for KERATIN-16 and the gene for KERATIN-6A.
] |
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Pachyrhizus
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D029905 |
[A plant genus of the family FABACEAE. Some Pachyrhizus have been reclassified to PUERARIA. Do not confuse with yam (IPOMOEA; or DIOSCOREA) or African yam bean (SPHENOSTYLIS).
] |
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Pachysandra
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D031236 |
[A plant genus of the family BUXACEAE that should not be confused with common spurge (EUPHORBIA).
] |
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Pachytene Stage
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D049471 |
[The stage in the first meiotic prophase, following ZYGOTENE STAGE, when CROSSING OVER between homologous CHROMOSOMES begins.
] |
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Pacific Islands
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D010139 |
[The islands of the Pacific Ocean divided into MICRONESIA; MELANESIA; and POLYNESIA (including NEW ZEALAND). The collective name Oceania includes the aforenamed islands, adding AUSTRALIA; NEW ZEALAND; and the Malay Archipelago (INDONESIA). (Webster's New Geographical Dictionary, 1988, p910, 880)
] |
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Pacific Ocean
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D010140 |
[Body of water between Asia and South America, extending from the Arctic circle to the Equator and from the Equator to the Antarctic.
] |
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Pacific States
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D019601 |
[The geographic designation for states bordering on or located in the Pacific Ocean. The states so designated are Alaska, California, Hawaii, Oregon, and Washington. (U.S. Geologic Survey telephone communication)
] |
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Pacifiers
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D041361 |
[Devices that babies can suck on when they are not feeding. The extra sucking can be comforting to the babies and pacify them. Pacifiers usually are used as a substitute for the thumb in babies who suck on their thumb or fingers almost constantly.
] |
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Pacinian Corpuscles
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D010141 |
[Rapidly adapting mechanoreceptors found in subcutaneous tissue beneath both hairy and glabrous skin. Pacinian corpuscles contain an afferent nerve fiber surrounded by a capsule with multiple concentric layers. They have large receptive fields and are most sensitive to high-frequency stimuli, such as vibration.
] |
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Paclitaxel
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D017239 |
[A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS BREVIFOLIA. It stabilizes MICROTUBULES in their polymerized form leading to cell death.
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Pactamycin
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D010142 |
[Antibiotic produced by Streptomyces pactum used as an antineoplastic agent. It is also used as a tool in biochemistry because it inhibits certain steps in protein synthesis.
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Paecilomyces
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D010143 |
[A mitosporic fungal genus occasionally causing human diseases such as pulmonary infections, mycotic keratitis, endocarditis, and opportunistic infections. Its teleomorph is BYSSOCHLAMYS.
] |
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Paenibacillus
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D056507 |
[A genus of GRAM-POSITIVE ENDOSPORE-FORMING RODS in the family Paenibacillaceae.
] |
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Paenibacillus larvae
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D000070059 |
[A species of Paenibacillus that causes American Foulbrood, a fatal disease of honeybees (APIS) and honeybee colonies.
] |
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Paenibacillus polymyxa
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D000070057 |
[A species of Paenibacillus formerly classified as Bacillus polymyxa that occurs in marine sediments and soil, especially around plant roots and RHIZOMES where it performs NITROGEN FIXATION. It has activity against several species of pathogenic bacteria and produces POLYMYXINS.
] |
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Paeonia
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D029596 |
[A plant genus of the family Paeoniaceae, order Dilleniales, subclass Dilleniidae, class Magnoliopsida. These perennial herbs are up to 2 m (6') tall. Leaves are alternate and are divided into three lobes, each lobe being further divided into three smaller lobes. The large flowers are symmetrical, bisexual, have 5 sepals, 5 petals (sometimes 10), and many stamens.
] |
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Paget Disease, Extramammary
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D010145 |
[A rare cutaneous neoplasm that occurs in the elderly. It develops more frequently in women and predominantly involves apocrine gland-bearing areas, especially the vulva, scrotum, and perianal areas. The lesions develop as erythematous scaly patches that progress to crusted, pruritic, erythematous plaques. The clinical differential diagnosis includes squamous cell carcinoma in situ and superficial fungal infection. It is generally thought to be an adenocarcinoma of the epidermis, from which it extends into the contiguous epithelium of hair follicles and eccrine sweat ducts. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1478)
] |
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Paget's Disease, Mammary
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D010144 |
[An intraductal in situ carcinoma of the breast, characterized clinically by eczema-like inflammatory skin changes and histologically by infiltration of the dermis by malignant cells (Paget's cells).
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Pagetoid Reticulosis
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D056267 |
[A distinct variant of mycosis fungoides characterized by the presence of localized patches or plaques with an intraepidermal proliferation of neoplastic cells.
, A generalized or disseminated form of pagetoid reticulosis. Some authors consider it to be a primary cutaneous aggressive epidermotrophic CD8+ T-Cell lymphoma.
] |
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Pain
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D010146 |
[An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
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