All individuals in MeSH

Label Id Description
Mitogen-Activated Protein Kinase 10 D048057 [A c-jun amino-terminal kinase that is found predominantly within NEURONS of the BRAIN, suggesting a role in stress-induced neuronal APOPTOSIS. Several isoforms of the protein with molecular sizes of 47 kDa and 52 kDa exist due to multiple ALTERNATIVE SPLICING. ]
Mitogen-Activated Protein Kinase 11 D048290 [A 38-kDa mitogen-activated protein kinase that is expressed in a broad variety of cell types. It may play a role in regulating cell proliferation and TRANSCRIPTION FACTOR AP-1 dependent transcription. ]
Mitogen-Activated Protein Kinase 12 D048291 [A 38-kDa mitogen-activated protein kinase found primarily in SKELETAL MUSCLE. ]
Mitogen-Activated Protein Kinase 13 D048292 [A 38-kDa mitogen-activated protein kinase found expressed at high levels in LUNG; KIDNEY; TESTIS; PANCREAS; and SMALL INTESTINE. It may play a role in regulating functions such as CELL DIFFERENTIATION and APOPTOSIS of EPITHELIAL CELLS. ]
Mitogen-Activated Protein Kinase 14 D048308 [A 38-kDa mitogen-activated protein kinase that is abundantly expressed in a broad variety of cell types. It is involved in the regulation of cellular stress responses as well as the control of proliferation and survival of many cell types. The kinase activity of the enzyme is inhibited by the pyridinyl-imidazole compound SB 203580. ]
Mitogen-Activated Protein Kinase 3 D048052 [A 44-kDa extracellular signal-regulated MAP kinase that may play a role the initiation and regulation of MEIOSIS; MITOSIS; and postmitotic functions in differentiated cells. It phosphorylates a number of TRANSCRIPTION FACTORS; and MICROTUBULE-ASSOCIATED PROTEINS. ]
Mitogen-Activated Protein Kinase 6 D048053 [A 97-kDa extracellular signal-regulated MAP kinase. Mitogen-activated protein kinase 6 levels increase during cellular differentiation, while in proliferating cells the enzyme is degraded rapidly via the PROTEASOME ENDOPEPTIDASE COMPLEX. ]
Mitogen-Activated Protein Kinase 7 D048054 [A 110-kDa extracellular signal-regulated MAP kinase that is activated in response to cellular stress and by GROWTH FACTOR RECEPTORS-mediated pathways. ]
Mitogen-Activated Protein Kinase 8 D048055 [A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokines. Several isoforms of the protein with molecular sizes of 43 and 48 KD exist due to multiple ALTERNATIVE SPLICING. ]
Mitogen-Activated Protein Kinase 9 D048056 [A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokines. Several isoforms of the protein with molecular sizes of 48 and 54 KD exist due to multiple ALTERNATIVE SPLICING. ]
Mitogen-Activated Protein Kinase Kinases D020929 [A serine-threonine protein kinase family whose members are components in protein kinase cascades activated by diverse stimuli. These MAPK kinases phosphorylate MITOGEN-ACTIVATED PROTEIN KINASES and are themselves phosphorylated by MAP KINASE KINASE KINASES. JNK kinases (also known as SAPK kinases) are a subfamily. ]
Mitogen-Activated Protein Kinase Phosphatases D054639 [A subcategory of phosphohydrolases that are specific for MITOGEN-ACTIVATED PROTEIN KINASES. They play a role in the inactivation of the MAP KINASE SIGNALING SYSTEM. ]
Mitogen-Activated Protein Kinases D020928 [A superfamily of PROTEIN-SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES). ]
Mitogens D008934 [Substances that stimulate mitosis and lymphocyte transformation. They include not only substances associated with LECTINS, but also substances from streptococci (associated with streptolysin S) and from strains of alpha-toxin-producing staphylococci. (Stedman, 25th ed) ]
Mitoguazone D008935 [Antineoplastic agent effective against myelogenous leukemia in experimental animals. Also acts as an inhibitor of animal S-adenosylmethionine decarboxylase. ]
Mitolactol D008936 [Alkylating antineoplastic toxic to bone marrow; used in breast cancer, also in combination with other drugs. ]
Mitomycin D016685 [An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis. ]
Mitomycins D008937 [A group of methylazirinopyrroloindolediones obtained from certain Streptomyces strains. They are very toxic antibiotics used as ANTINEOPLASTIC AGENTS in some solid tumors. PORFIROMYCIN and MITOMYCIN are the most useful members of the group. ]
Mitophagy D063306 [Proteolytic breakdown of the MITOCHONDRIA via autophagy. ]
Mitosis D008938 [A type of CELL NUCLEUS division by means of which the two daughter nuclei normally receive identical complements of the number of CHROMOSOMES of the somatic cells of the species. ]