All individuals in MeSH

Label Id Description
Mitochondrial Diseases D028361 [Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes. ]
Mitochondrial Dynamics D063154 [Merging of MITOCHONDRIA into tubular networks. , Division of MITOCHONDRIA. , The continuous remodeling of MITOCHONDRIA shape by fission and fusion in response to physiological conditions. ]
Mitochondrial Encephalomyopathies D017237 [A heterogenous group of disorders characterized by alterations of mitochondrial metabolism that result in muscle and nervous system dysfunction. These are often multisystemic and vary considerably in age at onset (usually in the first or second decade of life), distribution of affected muscles, severity, and course. (From Adams et al., Principles of Neurology, 6th ed, pp984-5) ]
Mitochondrial Membrane Transport Proteins D033681 [Proteins involved in the transport of specific substances across the membranes of the MITOCHONDRIA. ]
Mitochondrial Membranes D051336 [The two lipoprotein layers in the MITOCHONDRION. The outer membrane encloses the entire mitochondrion and contains channels with TRANSPORT PROTEINS to move molecules and ions in and out of the organelle. The inner membrane folds into cristae and contains many ENZYMES important to cell METABOLISM and energy production (MITOCHONDRIAL ATP SYNTHASE). ]
Mitochondrial Myopathies D017240 [A group of muscle diseases associated with abnormal mitochondria function. ]
Mitochondrial Permeability Transition Pore D000083162 [A multiprotein inner mitochondrial complex which opens only under certain pathological conditions (e.g., OXIDATIVE STRESS) uncoupling the membrane leading to APOPTOSIS and MITOCHONDRIAL TRANSMEMBRANE PERMEABILITY-DRIVEN NECROSIS particularly in CARDIOMYOCYTES during MYOCARDIAL REPERFUSION INJURY. ]
Mitochondrial Proteins D024101 [Proteins encoded by the mitochondrial genome or proteins encoded by the nuclear genome that are imported to and resident in the MITOCHONDRIA. ]
Mitochondrial Proton-Translocating ATPases D025261 [Proton-translocating ATPases responsible for ADENOSINE TRIPHOSPHATE synthesis in the MITOCHONDRIA. They derive energy from the respiratory chain-driven reactions that develop high concentrations of protons within the intermembranous space of the mitochondria. ]
Mitochondrial Replacement Therapy D000069321 [In vitro fertilization technique that uses mitochondrial DNA from a healthy donor in order to prevent the transmission of MITOCHONDRIAL DISEASE. ]
Mitochondrial Ribosomes D000069396 [Multicomponent ribonucleoprotein structures contained in MITOCHONDRIA that specialize in the PROTEIN BIOSYNTHESIS of a small number of proteins involved in energy production for the cell. ]
Mitochondrial Size D053142 [The quantity of volume or surface area of MITOCHONDRIA. ]
Mitochondrial Swelling D008933 [An increase in MITOCHONDRIAL VOLUME due to an influx of fluid; it occurs in hypotonic solutions due to osmotic pressure and in isotonic solutions as a result of altered permeability of the membranes of respiring mitochondria. ]
Mitochondrial Transmembrane Permeability-Driven Necrosis D000079530 [A form of regulated cell death that is initiated by specific perturbations of the intracellular microenvironment such as severe OXIDATIVE STRESS and cytosolic CALCIUM overload, which result in osmotic breakdown of the MITOCHONDRIAL MEMBRANES. ]
Mitochondrial Trifunctional Protein D063991 [A mitochondrial protein consisting of four alpha-subunits and four beta-subunits. It contains enoyl-CoA hydratase, long-chain-3-hydroxyacyl-CoA dehydrogenase, and acetyl-CoA C-acyltransferase activities and plays an important role in the metabolism of long chain FATTY ACIDS. ]
Mitochondrial Trifunctional Protein, alpha Subunit D063992 [The alpha subunit of mitochondrial trifunctional protein. It contains both enoyl-CoA hydratase activity (EC 4.2.1.17) and long-chain-3-hydroxyacyl-CoA dehydrogenase activity (EC 1.1.1.211). There are four of these alpha subunits in each mitochondrial trifunctional protein molecule. ]
Mitochondrial Trifunctional Protein, beta Subunit D063993 [The beta subunit of mitochondrial trifunctional protein that contains acetyl-CoA C-acyltransferase activity. There are four of these beta subunits in each trifunctional protein complex. ]
Mitochondrial Turnover D063269 [The cellular processes involved in adjustments to the MITOCHONDRIAL VOLUME, content, and activity, that depend on the energy demands of the cell. ]
Mitochondrial Uncoupling Proteins D000071245 [Mitochondrial anion carrier proteins that function as dimers and form proton channels in the INNER MITOCHONDRIAL MEMBRANE which creates proton leaks and uncouples OXIDATIVE PHOSPHORYLATION from ATP synthesis, resulting in the generation of heat instead of ATP. ]
Mitogen-Activated Protein Kinase 1 D019950 [A proline-directed serine/threonine protein kinase which mediates signal transduction from the cell surface to the nucleus. Activation of the enzyme by phosphorylation leads to its translocation into the nucleus where it acts upon specific transcription factors. p40 MAPK and p41 MAPK are isoforms. ]