|
Keratolytic Agents
|
D007641 |
[Agents that soften, separate, and cause desquamation of the cornified epithelium or horny layer of skin. They are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases.
] |
|
Keratomileusis, Laser In Situ
|
D020731 |
[A surgical procedure to correct MYOPIA by CORNEAL STROMA subtraction. It involves the use of a microkeratome to make a lamellar dissection of the CORNEA creating a flap with intact CORNEAL EPITHELIUM. After the flap is lifted, the underlying midstroma is reshaped with an EXCIMER LASER and the flap is returned to its original position.
] |
|
Keratoplasty, Penetrating
|
D015948 |
[Partial or total replacement of all layers of a central portion of the cornea.
] |
|
Keratosis
|
D007642 |
[Any horny growth such as a wart or callus.
] |
|
Keratosis, Actinic
|
D055623 |
[White or pink lesions on the arms, hands, face, or scalp that arise from sun-induced DNA DAMAGE to KERATINOCYTES in exposed areas. They are considered precursor lesions to superficial SQUAMOUS CELL CARCINOMA.
] |
|
Keratosis, Seborrheic
|
D017492 |
[Benign eccrine poromas that present as multiple oval, brown-to-black plaques, located mostly on the chest and back. The age of onset is usually in the fourth or fifth decade.
] |
|
Keratotomy, Radial
|
D007646 |
[A procedure to surgically correct REFRACTIVE ERRORS by cutting radial slits into the CORNEA to change its refractive properties.
] |
|
Kernicterus
|
D007647 |
[A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613)
] |
|
Kerosene
|
D007648 |
[A refined petroleum fraction used as a fuel as well as a solvent.
] |
|
Ketamine
|
D007649 |
[A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
] |
|
Ketanserin
|
D007650 |
[A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
] |
|
Keto Acids
|
D007651 |
[Carboxylic acids that contain a KETONE group.
] |
|
Ketocholesterols
|
D007653 |
[Cholesterol substituted in any position by a keto moiety. The 7-keto isomer inhibits cholesterol uptake in the coronary arteries and aorta by blocking 3-hydroxy-3-methylglutaryl-CoA reductase activity.
] |
|
Ketoconazole
|
D007654 |
[Broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients.
] |
|
Ketoglutarate Dehydrogenase Complex
|
D007655 |
|
|
Ketoglutaric Acids
|
D007656 |
[A family of compounds containing an oxo group with the general structure of 1,5-pentanedioic acid. (From Lehninger, Principles of Biochemistry, 1982, p442)
] |
|
Ketol-Acid Reductoisomerase
|
D050540 |
[An enzyme that catalyzes the oxidation of (R)-2,3-dihydroxy-3-methylbutanoate to (S)-2-hydroxy-2-methyl-3-oxobutanoate in the presence of NADP. It is involved in the biosynthesis of VALINE; LEUCINE; ISOLEUCINE; pentothenate and COENZYME A. This enzyme was formerly classified as EC 1.1.1.89.
] |
|
Ketolides
|
D048628 |
[Compounds based on ERYTHROMYCIN with the 3-cladinose replaced by a ketone. They bind the 23S part of 70S bacterial RIBOSOMES.
] |
|
Ketone Bodies
|
D007657 |
[The metabolic substances ACETONE; 3-HYDROXYBUTYRIC ACID; and acetoacetic acid (ACETOACETATES). They are produced in the liver and kidney during FATTY ACIDS oxidation and used as a source of energy by the heart, muscle and brain.
] |
|
Ketone Oxidoreductases
|
D007658 |
[Oxidoreductases that are specific for KETONES.
] |
