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Keratin-6
|
D053553 |
[A type II keratin found associated with KERATIN-16 or KERATIN-17 in rapidly proliferating squamous epithelial tissue. Mutations in gene for keratin-6A and keratin-6B have been associated with PACHYONYCHIA CONGENITA, TYPE 1 and PACHYONYCHIA CONGENITA, TYPE 2 respectively.
] |
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Keratin-7
|
D053552 |
[A type II keratin found associated with KERATIN-19 in ductal epithelia and gastrointestinal epithelia.
] |
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Keratin-8
|
D053533 |
[A type II keratin found associated with KERATIN-18 in simple, or predominately single layered, internal epithelia.
] |
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Keratin-9
|
D053534 |
[A type II keratin found predominantly expressed in the terminally differentiated EPIDERMIS of palms and soles. Mutations in the gene for keratin 9 are associated with KERATODERMA, PALMOPLANTAR, EPIDERMOLYTIC.
] |
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Keratinocytes
|
D015603 |
[Epidermal cells which synthesize keratin and undergo characteristic changes as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell.
] |
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Keratins
|
D007633 |
[A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
] |
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Keratins, Hair-Specific
|
D053564 |
[Keratins that are specific for hard tissues such as HAIR; NAILS; and the filiform papillae of the TONGUE.
] |
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Keratins, Type I
|
D053530 |
[A keratin subtype that includes keratins that are generally smaller and more acidic that TYPE II KERATINS. Type I keratins combine with type II keratins to form keratin filaments.
] |
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Keratins, Type II
|
D053531 |
[A keratin subtype that includes keratins that are generally larger and less acidic that TYPE I KERATINS. Type II keratins combine with type I keratins to form keratin filaments.
] |
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Keratitis
|
D007634 |
[Inflammation of the cornea.
] |
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Keratitis, Dendritic
|
D007635 |
[A form of herpetic keratitis characterized by the formation of small vesicles which break down and coalesce to form recurring dendritic ulcers, characteristically irregular, linear, branching, and ending in knoblike extremities. (Dictionary of Visual Science, 3d ed)
] |
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Keratitis, Herpetic
|
D016849 |
[A superficial, epithelial Herpesvirus hominis infection of the cornea, characterized by the presence of small vesicles which may break down and coalesce to form dendritic ulcers (KERATITIS, DENDRITIC). (Dictionary of Visual Science, 3d ed)
] |
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Keratoacanthoma
|
D007636 |
[A benign, non-neoplastic, usually self-limiting epithelial lesion closely resembling squamous cell carcinoma clinically and histopathologically. It occurs in solitary, multiple, and eruptive forms. The solitary and multiple forms occur on sunlight exposed areas and are identical histologically; they affect primarily white males. The eruptive form usually involves both sexes and appears as a generalized papular eruption.
] |
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Keratoconjunctivitis
|
D007637 |
[Simultaneous inflammation of the cornea and conjunctiva.
] |
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Keratoconjunctivitis Sicca
|
D007638 |
[Drying and inflammation of the conjunctiva as a result of insufficient lacrimal secretion. When found in association with XEROSTOMIA and polyarthritis, it is called SJOGREN'S SYNDROME.
] |
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Keratoconjunctivitis, Infectious
|
D007639 |
[Infectious diseases of cattle, sheep, and goats, characterized by blepharospasm, lacrimation, conjunctivitis, and varying degrees of corneal opacity and ulceration. In cattle the causative agent is MORAXELLA (MORAXELLA) BOVIS; in sheep, MYCOPLASMA; RICKETTSIA; CHLAMYDIA; or ACHOLEPLASMA; in goats, RICKETTSIA.
] |
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Keratoconus
|
D007640 |
[A noninflammatory, usually bilateral protrusion of the cornea, the apex being displaced downward and nasally. It occurs most commonly in females at about puberty. The cause is unknown but hereditary factors may play a role. The -conus refers to the cone shape of the corneal protrusion. (From Dorland, 27th ed)
] |
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Keratoderma, Palmoplantar
|
D007645 |
[Group of mostly hereditary disorders characterized by thickening of the palms and soles as a result of excessive keratin formation leading to hypertrophy of the stratum corneum (hyperkeratosis).
] |
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Keratoderma, Palmoplantar, Diffuse
|
D015776 |
[An autosomal dominant disorder characterized by a widely distributed, well-demarcated hyperkeratosis of the palms and soles. There is more than one genotypically distinct form, each of which is clinically similar but histologically distinguishable. Diffuse palmoplantar keratoderma is distinct from palmoplantar keratoderma (KERATODERMA, PALMOPLANTAR), as the former exhibits autosomal dominant inheritance and hyperhidrosis is frequently present.
] |
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Keratoderma, Palmoplantar, Epidermolytic
|
D053546 |
[An autosomal dominant hereditary skin disease characterized by epidermolytic hyperkeratosis that is strictly confined to the palms and soles. It has been associated with mutations in the gene that codes for KERATIN-9.
] |
