|
Kartagener Syndrome
|
D007619 |
[An autosomal recessive disorder characterized by a triad of DEXTROCARDIA; INFERTILITY; and SINUSITIS. The syndrome is caused by mutations of DYNEIN genes encoding motility proteins which are components of sperm tails, and CILIA in the respiratory and the reproductive tracts.
] |
|
Karwinskia
|
D031956 |
[A plant genus of the family RHAMNACEAE that contains tullidinol (toxin T-544) and peroxisomicine (toxin T-514). It is sometimes called buckthorn but should not be confused with other plants called that.
] |
|
Karyometry
|
D007620 |
[Microscopic study of the spacial distribution pattern of CHROMATIN in CELL NUCLEI and CELL NUCLEOLI.
] |
|
Karyopherins
|
D028884 |
[A subclass of karyopherins that function specifically to export molecules into the nucleus.
, A subclass of karyopherins that function specifically to import molecules into the nucleus.
, A family of proteins involved in NUCLEOCYTOPLASMIC TRANSPORT. Karyopherins are heteromeric molecules composed of two major types of components, ALPHA KARYOPHERINS and BETA KARYOPHERINS, that function together to transport molecules through the NUCLEAR PORE COMPLEX. Several other proteins such as RAN GTP BINDING PROTEIN and CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN bind to karyopherins and participate in the transport process.
] |
|
Karyotype
|
D059785 |
[The full set of CHROMOSOMES presented as a systematized array of METAPHASE chromosomes from a photomicrograph of a single CELL NUCLEUS arranged in pairs in descending order of size and according to the position of the CENTROMERE. (From Stedman, 25th ed)
] |
|
Karyotyping
|
D007621 |
[Mapping of the KARYOTYPE of a cell.
] |
|
Kasabach-Merritt Syndrome
|
D059885 |
[Rapidly growing vascular lesion along the midline axis of the neck, upper trunk, and extremities that is characterized by CONSUMPTION COAGULOPATHY; THROMBOCYTOPENIA; and HEMOLYTIC ANEMIA. It is often associated with infantile Kaposiform HEMANGIOENDOTHELIOMA and other vascular tumors such as tufted ANGIOMA.
] |
|
Kashin-Beck Disease
|
D057767 |
[Disabling osteochondrodysplasia with OSTEOSCLEROSIS, cone-shaped METAPHYSIS, and shortening of the DIAPHYSIS. It is endemic in parts of Siberia and northern China. Mineral deficiencies (e.g., selenium, iodine), fungal cereal contamination, and water contamination may be contributing factors in its etiology.
] |
|
Kassinin
|
D015286 |
[Dodecapeptide tachykinin found in the central nervous system of the amphibian Kassina senegalensis. It is similar in structure and action to other tachykinins, but is especially effective in contracting smooth muscle tissue and stimulating the micturition reflex.
] |
|
Katanin
|
D000074201 |
[An enzyme (AAA ATPase) consisting of the 60 kDa ATPase subunit (p60 subunit A1) which severs MICROTUBULES, and an 80 kDa accessory protein (p80 subunit B1), which targets the enzyme to the CENTROSOME. It releases microtubules from the mitotic SPINDLE POLES to allow depolymerization and poleward motion of chromosomes. It is also a regulator of microtubule dynamics in NEURONAL OUTGROWTH.
] |
|
Kava
|
D020901 |
[Dried rhizome and roots of Piper methysticum, a shrub native to Oceania and known for its anti-anxiety and sedative properties. Heavy usage results in some adverse effects. It contains ALKALOIDS; LACTONES; kawain, methysticin, mucilage, STARCH, and yangonin. Kava is also the name of the pungent beverage prepared from the plant's roots.
] |
|
Kazakhstan
|
D007623 |
[A country in central Asia, northwest of China. The capital is Astana.
] |
|
Kazal Motifs
|
D000074161 |
[Highly conserved protein domains characteristic of SERINE PROTEASE INHIBITORS, KAZAL TYPE. They generally occur as tandem repeats, with each domain consisting of approximately 60 amino acids that form a large extended amino acid chain, two short ALPHA-HELICES, and a three-stranded anti-parallel BETA-SHEET. Kazal-like domains also occur in the extracellular portions of AGRIN.
] |
|
Kearns-Sayre Syndrome
|
D007625 |
[A mitochondrial disorder featuring the triad of chronic progressive EXTERNAL OPHTHALMOPLEGIA, cardiomyopathy (CARDIOMYOPATHIES) with conduction block (HEART BLOCK), and RETINITIS PIGMENTOSA. Disease onset is in the first or second decade. Elevated CSF protein, sensorineural deafness, seizures, and pyramidal signs may also be present. Ragged-red fibers are found on muscle biopsy. (Adams et al., Principles of Neurology, 6th ed, p984)
] |
|
Kefir
|
D000070716 |
[Symbiotic associations of different, predominantly LACTIC ACID-producing bacteria and yeast that exist in a polysaccharide and protein matrix, forming small grain-like aggregates in KEFIR.
, A beverage made from milk fermented by a mixture of endogenous LACTIC ACID-producing yeast and bacteria (KEFIR GRAINS), many of which are PROBIOTICS. It should not be confused with KAFFIR LIME or KAFFIR CORN.
] |
|
Kelch Repeat
|
D000071776 |
[An amino acid sequence of about 50 residues long that is composed of X n-long repeats which form a four-stranded anti-parallel BETA-SHEET as a structural component, or blade, of a beta-propeller.
] |
|
Kelch-Like ECH-Associated Protein 1
|
D000072019 |
[An adaptor protein characterized by an N-terminal BTB-POZ DOMAIN and six KELCH REPEATS that functions as a substrate for the E3 UBIQUITIN LIGASE complex. It negatively-regulates NF-E2-RELATED FACTOR 2 by targeting it for ubiquitination and degradation by the PROTEASOME. It also represses genes regulated by ANTIOXIDANT RESPONSE ELEMENTS.
] |
|
Kell Blood-Group System
|
D007626 |
[Multiple erythrocytic antigens that comprise at least three pairs of alternates and amorphs, determined by one complex gene or possibly several genes at closely linked loci. The system is important in transfusion reactions. Its expression involves the X-chromosome.
] |
|
Keloid
|
D007627 |
[A sharply elevated, irregularly shaped, progressively enlarging scar resulting from formation of excessive amounts of collagen in the dermis during connective tissue repair. It is differentiated from a hypertrophic scar (CICATRIX, HYPERTROPHIC) in that the former does not spread to surrounding tissues.
] |
|
Kelp
|
D044423 |
[Large, robust forms of brown algae (PHAEOPHYCEAE) in the order Laminariales. They are a major component of the lower intertidal and sublittoral zones on rocky coasts in temperate and polar waters. Kelp, a kind of SEAWEED, usually refers to species in the genera LAMINARIA or MACROCYSTIS, but the term may also be used for species in FUCUS or Nereocystis.
] |
