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Kainic Acid
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D007608 |
[(2S-(2 alpha,3 beta,4 beta))-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid. Ascaricide obtained from the red alga Digenea simplex. It is a potent excitatory amino acid agonist at some types of excitatory amino acid receptors and has been used to discriminate among receptor types. Like many excitatory amino acid agonists it can cause neurotoxicity and has been used experimentally for that purpose.
] |
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Kalanchoe
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D031962 |
[A plant genus of the family CRASSULACEAE. Members contain bryophyllins (also called bryotoxins) which are bufadienolides (BUFANOLIDES) that have insecticidal activity.
, A section of around two dozen species in the plant genus Kalanchoe.
] |
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Kallidin
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D007609 |
[A decapeptide bradykinin homolog cleaved from kininogen by kallikreins. It is a smooth-muscle stimulant and hypotensive agent that acts by vasodilatation.
] |
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Kallikrein-Kinin System
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D016234 |
[A system of metabolic interactions by products produced in the distal nephron of the KIDNEY. These products include KALLIKREIN; KININS; KININASE I; KININASE II; and ENKEPHALINASE. This system participates in the control of renal functions. It interacts with the RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM to regulate BLOOD PRESSURE, generation of PROSTAGLANDINS, release of VASOPRESSINS, and WATER-ELECTROLYTE BALANCE.
] |
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Kallikreins
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D007610 |
[Proteolytic enzymes from the serine endopeptidase family found in normal blood and urine. Specifically, Kallikreins are potent vasodilators and hypotensives and increase vascular permeability and affect smooth muscle. They act as infertility agents in men. Three forms are recognized, PLASMA KALLIKREIN (EC 3.4.21.34), TISSUE KALLIKREIN (EC 3.4.21.35), and PROSTATE-SPECIFIC ANTIGEN (EC 3.4.21.77).
] |
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Kallmann Syndrome
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D017436 |
[Type 1 is the X-linked form with mutations of gene Kal1 which encodes anosmin-1 protein that plays a key role in the migration of GNRH-containing neurons and olfactory nerves to the HYPOTHALAMUS.
, Type 2 is an autosomal dominant form with loss-of-function mutations of gene Kal2 which encodes fibroblast growth-factor receptor-1 (FGFR1 PROTEIN).
, A genetically heterogeneous disorder caused by hypothalamic GNRH deficiency and OLFACTORY NERVE defects. It is characterized by congenital HYPOGONADOTROPIC HYPOGONADISM and ANOSMIA, possibly with additional midline defects. It can be transmitted as an X-linked (GENETIC DISEASES, X-LINKED), an autosomal dominant, or an autosomal recessive trait.
] |
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Kalopanax
|
D036882 |
[A plant genus of the family ARALIACEAE. Members contain triterpene saponins.
] |
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Kanamycin
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D007612 |
[Antibiotic complex produced by Streptomyces kanamyceticus from Japanese soil. Comprises 3 components: kanamycin A, the major component, and kanamycins B and C, the minor components.
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Kanamycin Kinase
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D019868 |
[A class of enzymes that inactivate aminocyclitol-aminoglycoside antibiotics (AMINOGLYCOSIDES) by regiospecific PHOSPHORYLATION of the 3' and/or 5' hydroxyl.
] |
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Kanamycin Resistance
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D007613 |
[Nonsusceptibility of bacteria to the antibiotic KANAMYCIN, which can bind to their 70S ribosomes and cause misreading of messenger RNA.
] |
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Kangai-1 Protein
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D051861 |
[A widely expressed transmembrane glycoprotein that functions as a METASTASIS suppressor protein. It is underexpressed in a variety of human NEOPLASMS.
] |
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Kangaroo-Mother Care Method
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D060127 |
[A method of continuously holding a partially wrapped baby to the chest, involving skin-to-skin contact. Originally it was a method of caring for LOW-BIRTH-WEIGHT INFANT in developing countries and is now more widespread in developed nations. Aside from encouraging breast feeding, the extra sleep that the infant gets assists in regulating body temperature, helps the baby conserve energy, and redirects calorie expenditures toward growth and weight gain.
] |
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Kansas
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D007615 |
[State bounded on the north by Nebraska on the east by Missouri, on the south by Oklahoma, and on the west by Colorado.
] |
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Kaolin
|
D007616 |
[The most common mineral of a group of hydrated aluminum silicates, approximately H2Al2Si2O8-H2O. It is prepared for pharmaceutical and medicinal purposes by levigating with water to remove sand, etc. (From Merck Index, 11th ed) The name is derived from Kao-ling (Chinese: "high ridge"), the original site. (From Grant & Hackh's Chemical Dictionary, 5th ed)
] |
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Kaplan-Meier Estimate
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D053208 |
[A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)
] |
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Kaposi Varicelliform Eruption
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D007617 |
[A disseminated vesicular-pustular eruption caused by the herpes simplex virus (HERPESVIRUS HOMINIS), the VACCINIA VIRUS, or Varicella zoster (HERPESVIRUS 3, HUMAN). It is usually superimposed on a preexisting, inactive or active, atopic dermatitis (DERMATITIS, ATOPIC).
] |
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Kappapapillomavirus
|
D052690 |
[A genus of DNA viruses in the family PAPILLOMAVIRIDAE, causing cutaneous and mucosal lesions in rabbits. COTTONTAIL RABBIT PAPILLOMAVIRUS is the type species.
] |
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Karaya Gum
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D007618 |
[Polysaccharide gum from Sterculia urens (STERCULIA). It is used as a suspending or stabilizing agent in foods, cosmetics and pharmaceuticals; a bulk-forming laxative; a surgical lubricant and adhesive; and in the treatment of skin ulcers.
] |
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Karnofsky Performance Status
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D017567 |
[A performance measure for rating the ability of a person to perform usual activities, evaluating a patient's progress after a therapeutic procedure, and determining a patient's suitability for therapy. It is used most commonly in the prognosis of cancer therapy, usually after chemotherapy and customarily administered before and after therapy. It was named for Dr. David A. Karnofsky, an American specialist in cancer chemotherapy.
] |
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Karoshi Death
|
D065907 |
[Sudden death from overwork, most often as a result of acute CARDIOVASCULAR STROKE.
] |
