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Isolated Heart Preparation
|
D000067268 |
[Method of isolation and maintenance of a working heart for various cardiac measurements. The model allows for the separation of cardiac and systemic variables in the denervated heart.
] |
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Isolated Noncompaction of the Ventricular Myocardium
|
D056830 |
[Mutations in the tafazzin gene are associated with X-Linked Isolated Noncompaction of the Left Ventricular Myocardium. BARTH SYNDROME is an allelic disorder.
, Rare congenital cardiomyopathies characterized by the lack of left ventricular myocardium compaction. The noncompaction results in numerous prominent trabeculations and a loose myocardial meshwork (spongy myocardium) in the LEFT VENTRICLE. Heterogeneous clinical features include diminished systolic function sometimes associated with left ventricular dilation, that presents either neonatally or progressively. Often, the RIGHT VENTRICLE is also affected. CONGESTIVE HEART FAILURE; PULMONARY EMBOLISM; and ventricular ARRHYTHMIA are commonly seen.
, Mutations in the alpha-dystrobrevin gene are associated with Autosomal Dominant type of Noncompaction of the Left Ventricular Myocardium.
] |
|
Isoleucine
|
D007532 |
[An essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of LEUCINE. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.
] |
|
Isoleucine-tRNA Ligase
|
D007533 |
[An enzyme that activates isoleucine with its specific transfer RNA. EC 6.1.1.5.
] |
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Isomaltose
|
D007534 |
[A disaccharide consisting of two glucose units in an alpha (1-6) glycosidic linkage.
] |
|
Isomerases
|
D007535 |
[A class of enzymes that catalyze geometric or structural changes within a molecule to form a single product. The reactions do not involve a net change in the concentrations of compounds other than the substrate and the product.(from Dorland, 28th ed) EC 5.
] |
|
Isomerism
|
D007536 |
[The phenomenon whereby certain chemical compounds have structures that are different although the compounds possess the same elemental composition. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
] |
|
Isometric Contraction
|
D007537 |
[Muscular contractions characterized by increase in tension without change in length.
] |
|
Isoniazid
|
D007538 |
[Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
] |
|
Isonicotinic Acids
|
D007539 |
[Heterocyclic acids that are derivatives of 4-pyridinecarboxylic acid (isonicotinic acid).
] |
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Isonipecotic Acids
|
D007540 |
|
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Isopentenyladenosine
|
D007541 |
[N(6)-[delta(3)-isopentenyl]adenosine. Isopentenyl derivative of adenosine which is a member of the cytokinin family of plant growth regulators.
] |
|
Isophane Insulin, Human
|
D000068880 |
[Human isophane insulin that is used to manage BLOOD GLUCOSE levels in patients with DIABETES.
] |
|
Isopoda
|
D033321 |
[One of the largest orders of mostly marine CRUSTACEA, containing over 10,000 species. Like AMPHIPODA, the other large order in the superorder Peracarida, members are shrimp-like in appearance, have sessile compound eyes, and no carapace. But unlike Amphipoda, they possess abdominal pleopods (modified as gills) and their bodies are dorsoventrally flattened.
] |
|
Isopropyl Thiogalactoside
|
D007544 |
[A non-metabolizable galactose analog that induces expression of the LAC OPERON.
] |
|
Isoprostanes
|
D028421 |
[A series of prostaglandin-like compounds that are produced by the attack of free-radical species on unsaturated fatty acids, especially ARACHIDONIC ACID, of cellular MEMBRANES. Once cleaved from the lipid membrane by the action of phospholipases they can circulate into various bodily fluids and eventually be excreted. Although these compounds resemble enzymatically synthesized prostaglandins their stereoisometric arrangement is usually different than the "naturally occurring" compounds.
] |
|
Isoproterenol
|
D007545 |
[Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
] |
|
Isoptera
|
D020049 |
[An order of insects, restricted mostly to the tropics, containing at least eight families. A few species occur in temperate regions of North America.
] |
|
Isoquinolines
|
D007546 |
[A group of compounds with the heterocyclic ring structure of benzo(c)pyridine. The ring structure is characteristic of the group of opium alkaloids such as papaverine. (From Stedman, 25th ed)
] |
|
Isosorbide
|
D007547 |
[1,4:3,6-Dianhydro D-glucitol. Chemically inert osmotic diuretic used mainly to treat hydrocephalus; also used in glaucoma.
] |
