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Disinfection
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D004203 |
[Rendering pathogens harmless through the use of heat, antiseptics, antibacterial agents, etc.
] |
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Disintegrins
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D019483 |
[A family of polypeptides purified from snake venoms, which contain the arginine-glycine-aspartic acid (RGD) sequence. The RGD tripeptide binds to integrin receptors and thus competitively inhibits normal integrin-ligand interactions. Disintegrins thus block adhesive functions and act as platelet aggregation inhibitors.
] |
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Disk Diffusion Antimicrobial Tests
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D052978 |
[A method where a culturing surface inoculated with microbe is exposed to small disks containing known amounts of a chemical agent resulting in a zone of inhibition (usually in millimeters) of growth of the microbe corresponding to the susceptibility of the strain to the agent.
] |
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Diskectomy
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D017586 |
[Excision, in part or whole, of an INTERVERTEBRAL DISC. The most common indication is disk displacement or herniation. In addition to standard surgical removal, it can be performed by percutaneous diskectomy (DISKECTOMY, PERCUTANEOUS) or by laparoscopic diskectomy, the former being the more common.
] |
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Diskectomy, Percutaneous
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D017587 |
[Percutaneous excision of a herniated or displaced INTERVERTEBRAL DISC by posterolateral approach, always remaining outside the spinal canal. Percutaneous nucleotomy was first described by Hijikata in Japan in 1975. In 1985 Onik introduced automated percutaneous nucleotomy which consists in percutaneous aspiration of the nucleus pulposus. It is carried out under local anesthesia, thus reducing the surgical insult and requiring brief hospitalization, often performed on an outpatient basis. It appears to be a well-tolerated alternative to surgical diskectomy and chymopapain nucleolysis.
] |
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Disks Large Homolog 4 Protein
|
D000076122 |
[A neuronal protein consisting of three PDZ DOMAINS, an SH3 DOMAIN, and a C-terminal guanylate kinase-like region (see MAGUK PROTEINS). It localizes to the POST-SYNAPTIC DENSITY and associates with the cytoplasmic tail of NMDA RECEPTORS and SHAKER POTASSIUM CHANNELS, playing a critical role in NMDA receptor-mediated SYNAPTIC PLASTICITY.
] |
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Disopyramide
|
D004206 |
[A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
] |
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Disorder of Sex Development, 46,XY
|
D058490 |
[Congenital conditions in individuals with a male karyotype, in which the development of the gonadal or anatomical sex is atypical.
] |
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Disorders of Environmental Origin
|
D007280 |
[Disorders caused by external forces rather than by physiologic dysfunction or by pathogens.
] |
|
Disorders of Excessive Somnolence
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D006970 |
[Disorders characterized by hypersomnolence during normal waking hours that may impair cognitive functioning. Subtypes include primary hypersomnia disorders (e.g., IDIOPATHIC HYPERSOMNOLENCE; NARCOLEPSY; and KLEINE-LEVIN SYNDROME) and secondary hypersomnia disorders where excessive somnolence can be attributed to a known cause (e.g., drug affect, MENTAL DISORDERS, and SLEEP APNEA SYNDROME). (From J Neurol Sci 1998 Jan 8;153(2):192-202; Thorpy, Principles and Practice of Sleep Medicine, 2nd ed, p320)
] |
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Disorders of Sex Development
|
D012734 |
[An historical term for a variety of abnormalities in sex development that lead to anomalies in the reproductive tract and/or external genitalia.
, In gonochoristic organisms, congenital conditions in which development of chromosomal, gonadal, or anatomical sex is atypical. Effects from exposure to abnormal levels of GONADAL HORMONES in the maternal environment, or disruption of the function of those hormones by ENDOCRINE DISRUPTORS are included.
] |
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Dispensatories as Topic
|
D004207 |
[Works about systematic description of the drugs and preparations used generally or in a specific setting.
] |
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Dispensatory
|
D000077202 |
[Systematic description of the drugs and preparations used generally or in a specific setting.
] |
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Displacement, Psychological
|
D004208 |
[The process by which an emotional or behavioral response that is appropriate for one situation appears in another situation for which it is inappropriate.
] |
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Disposable Equipment
|
D004209 |
[Apparatus, devices, or supplies intended for one-time or temporary use.
] |
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Disruptive Technology
|
D000079203 |
[A process by which a product or service takes root initially in simple applications at the bottom of a market and then relentlessly moves up market, eventually displacing established competitors. (http://www.claytonchristensen.com/key-concepts)
] |
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Disruptive, Impulse Control, and Conduct Disorders
|
D007174 |
[Disorders whose essential features are the failure to resist an impulse, drive, or temptation to perform an act that is harmful to the individual or to others. Individuals experience an increased sense of tension prior to the act and pleasure, gratification or release of tension at the time of committing the act.
] |
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Dissection
|
D004210 |
[The separation and isolation of tissues for surgical purposes, or for the analysis or study of their structures.
] |
|
Disseminated Intravascular Coagulation
|
D004211 |
[A disorder characterized by procoagulant substances entering the general circulation causing a systemic thrombotic process. The activation of the clotting mechanism may arise from any of a number of disorders. A majority of the patients manifest skin lesions, sometimes leading to PURPURA FULMINANS.
] |
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Dissent and Disputes
|
D034462 |
[Differences of opinion or disagreements that may arise, for example, between health professionals and patients or their families, or against a political regime.
] |