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Disease
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D004194 |
[A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown.
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Disease Attributes
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D020969 |
[Clinical characteristics of disease or illness.
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Disease Eradication
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D060740 |
[Termination of all transmission of infection by global extermination of the infectious agent through surveillance and containment (From Porta, A Dictionary of Epidemiology, 5th ed).
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Disease Hotspot
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D000086822 |
[Areas of increased disease risk, prevalence, incidence or higher efficiency of transmission.
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Disease Management
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D019468 |
[A broad approach to appropriate coordination of the entire disease treatment process that often involves shifting away from more expensive inpatient and acute care to areas such as preventive medicine, patient counseling and education, and outpatient care. This concept includes implications of appropriate versus inappropriate therapy on the overall cost and clinical outcome of a particular disease. (From Hosp Pharm 1995 Jul;30(7):596)
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Disease Models, Animal
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D004195 |
[Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
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Disease Notification
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D018563 |
[Notification or reporting by a physician or other health care provider of the occurrence of specified contagious diseases such as tuberculosis and HIV infections to designated public health agencies. The United States system of reporting notifiable diseases evolved from the Quarantine Act of 1878, which authorized the US Public Health Service to collect morbidity data on cholera, smallpox, and yellow fever; each state in the US has its own list of notifiable diseases and depends largely on reporting by the individual health care provider. (From Segen, Dictionary of Modern Medicine, 1992)
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Disease Outbreaks
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D004196 |
[Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.
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Disease Progression
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D018450 |
[The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
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Disease Reservoirs
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D004197 |
[Animate or inanimate sources which normally harbor disease-causing organisms and thus serve as potential sources of disease outbreaks. Reservoirs are distinguished from vectors (DISEASE VECTORS) and carriers, which are agents of disease transmission rather than continuing sources of potential disease outbreaks. Humans may serve both as disease reservoirs and carriers.
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Disease Resistance
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D060467 |
[The capacity of an organism to defend itself against pathological processes or the agents of those processes. This most often involves innate immunity whereby the organism responds to pathogens in a generic way. The term disease resistance is used most frequently when referring to plants.
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Disease Susceptibility
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D004198 |
[A constitution or condition of the body which makes the tissues react in special ways to certain extrinsic stimuli and thus tends to make the individual more than usually susceptible to certain diseases.
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Disease Transmission, Infectious
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D018562 |
[The transmission of infectious disease or pathogens. When transmission is within the same species, the mode can be horizontal or vertical (INFECTIOUS DISEASE TRANSMISSION, VERTICAL).
, The transmission of infectious disease or pathogens from one individual to another.
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Disease Vectors
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D004199 |
[Invertebrates or non-human vertebrates which transmit infective organisms from one host to another.
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Disease-Free Survival
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D018572 |
[Period after successful treatment in which there is no appearance of the symptoms or effects of the disease.
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Diseases in Twins
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D004200 |
[Disorders affecting TWINS, one or both, at any age.
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Disenfranchised Grief
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D000076605 |
[Expression of grief that society limits or may not allow a person to express. Examples include the grief of parents for stillborn babies, of teachers for the death of students, of nurses for the death of patients, or for the loss of an animal companion. (from APA Dictionary of Psychology, 2nd ed.)
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Disgust
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D000078382 |
[A feeling of revulsion or strong disapproval aroused by something unpleasant or offensive.
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Dishevelled Proteins
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D000072261 |
[A family of proteins that are key components of the WNT SIGNALING PATHWAY, where they function downstream of FRIZZLED RECEPTORS. They contain an N-terminal dishevelled-AXIN PROTEIN (DIX) domain, which mediates oligomerization; a central PDZ DOMAIN which binds to the frizzled receptor; and a C-terminal DEP domain which facilitates binding to the CELL MEMBRANE. Dishevelled proteins have important functions in CELL DIFFERENTIATION and establishing CELL POLARITY.
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Disinfectants
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D004202 |
[Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity. Disinfectants are classed as complete, destroying SPORES as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms. They are distinguished from ANTISEPTICS, which are local anti-infective agents used on humans and other animals. (From Hawley's Condensed Chemical Dictionary, 11th ed)
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