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D-Amino-Acid Oxidase
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D003605 |
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D-Aspartate Oxidase
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D050804 |
[An FAD-dependent peroxisomal flavoenzyme, this catalyzes the oxidative deamination of D-ASPARTATE to OXALOACETATE and AMMONIA using oxygen as electron acceptor.
] |
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D-Aspartic Acid
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D026603 |
[The D-isomer of ASPARTIC ACID.
] |
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D-Xylulose Reductase
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D050542 |
[An enzyme that plays a role in the PENTOSES and GLUCURONATES interconversion pathway by catalyzing the oxidation of XYLITOL to D-xylulose. This enzyme has been found to be specific for NAD+.
] |
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DAX-1 Orphan Nuclear Receptor
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D057137 |
[An orphan nuclear receptor that is implicated in regulation of steroidogenic pathways. It is unlike most orphan nuclear receptors in that it appears to lack an essential DNA-binding domain and instead acts as a transcriptional co-repressor. Mutations in the gene Dax-1 cause congenital adrenal hypoplasia.
] |
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DCC Receptor
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D000075389 |
[A receptor for NETRIN-1 that contains four membrane distal (N-terminal) Ig-like C2 domains and six membrane proximal (C-terminal) fibronectin type III domains. It is expressed primarily in the nerve axons and differentiated intestinal cells and is required for AXON GUIDANCE, mediating axon attraction of neuronal GROWTH CONES; however, it may also trigger axon repulsion through association with the UNC5 netrin-1 receptor. DCC also induces APOPTOSIS when it is unbound from netrin-1. Deletions of the DCC gene are observed in tumor metastases and the protein is not expressed in undifferentiated COLORECTAL CARCINOMA cells.
] |
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DCMP Deaminase
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D003844 |
[An enzyme that catalyzes the hydrolytic deamination of deoxycytidylic acid to deoxyuridylic acid and ammonia. It plays an important role in the regulation of the pool of deoxynucleotides in higher organisms. The enzyme also acts on some 5-substituted deoxycytidylic acids. EC 3.5.4.12.
] |
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DDT
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D003634 |
[A polychlorinated pesticide that is resistant to destruction by light and oxidation. Its unusual stability has resulted in difficulties in residue removal from water, soil, and foodstuffs. This substance may reasonably be anticipated to be a carcinogen: Fourth Annual Report on Carcinogens (NTP-85-002, 1985). (From Merck Index, 11th ed)
] |
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DEAD Box Protein 20
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D055541 |
[A multifunctional protein that is both a DEAD-box RNA helicase and a component of the SMN protein complex.
] |
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DEAD Box Protein 58
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D000071457 |
[A DEAD-box RNA helicase that contains an N-terminal DEATH-LIKE DOMAIN, AAA+ ATPase domain, and C-terminal RNA HELICASE activity. It functions as an innate immune receptor through its recognition of viral nucleic acids. It also induces the expression of INTERFERON TYPE I and proinflammatory CYTOKINES. Its ligands include: 5'-triphosphorylated SINGLE-STRANDED RNA, DOUBLE-STRANDED RNA (dsRNA), and short dsRNA (less than 1 kb in length).
] |
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DEAD-box RNA Helicases
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D053487 |
[A large family of RNA helicases that share a common protein motif with the single letter amino acid sequence D-E-A-D (Asp-Glu-Ala-Asp). In addition to RNA helicase activity, members of the DEAD-box family participate in other aspects of RNA metabolism and regulation of RNA function.
] |
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DEAE-Cellulose
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D003636 |
[Cellulose derivative used in chromatography, as ion-exchange material, and for various industrial applications.
] |
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DEAE-Dextran
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D003637 |
[Used as a support for ion-exchange chromatography.
] |
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DEET
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D003671 |
[A compound used as a topical insect repellent that may cause irritation to eyes and mucous membranes, but not to the skin.
] |
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DEFICIENS Protein
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D026281 |
[DEFICIENS is a homeotic gene involved in the genetic control of Antirrhinum majus flower development. Its protein is one of the four founder proteins that structurally define the superfamily of MADS DOMAIN PROTEINS.
] |
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DMF Index
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D004245 |
["Decayed, missing and filled teeth," a routinely used statistical concept in dentistry.
] |
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DNA
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D004247 |
[A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).
] |
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DNA (Cytosine-5-)-Methyltransferase 1
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D000076123 |
[A DNA (cytosine-5-)-methyltransferase that contains a central CxxC type zinc finger motif. It binds poly(ADP)-ribose and its expression is regulated by POLY (ADP-RIBOSE) POLYMERASE-1. DNMT1 methylates CpG residues, with a preference for hemimethylated DNA, and associates with DNA replication sites in S PHASE to maintain the methylation pattern in the newly synthesized strand, which is essential for EPIGENETIC PROCESSES. It also associates with CHROMATIN during G2 PHASE and MITOSIS to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development; mutations in the DNMT1 gene are associated with HEREDITARY SENSORY NEUROPATHY TYPE 1 class E.
] |
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DNA (Cytosine-5-)-Methyltransferases
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D004248 |
[Enzymes that catalyzes the transfer of a methyl group from S-ADENOSYLMETHIONINE to the 5-position of CYTOSINE residues in DNA.
] |
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DNA Adducts
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D018736 |
[The products of chemical reactions that result in the addition of extraneous chemical groups to DNA.
] |
