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Steroids, Chlorinated
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D013258 |
[Steroids which are substituted with one or more chlorine atoms in any position.
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Steroids, Fluorinated
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D013259 |
[Steroids which are substituted with one or more fluorine atoms in any position.
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Steroids, Heterocyclic
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D013260 |
[Steroidal compounds in which one or more carbon atoms in the steroid ring system have been substituted with non-carbon atoms.
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Sterol 14-Demethylase
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D058886 |
[An NADPH-dependent P450 enzyme that plays an essential role in the sterol biosynthetic pathway by catalyzing the demethylation of 14-methyl sterols such as lanosterol. The enzyme acts via the repeated hydroxylation of the 14-methyl group, resulting in its stepwise conversion into an alcohol, an aldehyde and then a carboxylate, which is removed as formic acid. Sterol 14-demethylase is an unusual cytochrome P450 enzyme in that it is found in a broad variety of organisms including ANIMALS; PLANTS; FUNGI; and protozoa.
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Sterol Esterase
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D002787 |
[An enzyme that catalyzes the hydrolysis of CHOLESTEROL ESTERS and some other sterol esters, to liberate cholesterol plus a fatty acid anion.
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Sterol O-Acyltransferase
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D002785 |
[An enzyme that catalyzes the formation of cholesterol esters by the direct transfer of the fatty acid group from a fatty acyl CoA derivative. This enzyme has been found in the adrenal gland, gonads, liver, intestinal mucosa, and aorta of many mammalian species. EC 2.3.1.26.
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Sterol Regulatory Element Binding Protein 1
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D051780 |
[SREBP1-A is an isoform of sterol regulatory element binding protein 1 that is a potent activator of GENETIC TRANSCRIPTION. It is the predominant form in SPLEEN.
, A sterol regulatory element binding protein that regulates expression of GENES involved in FATTY ACIDS metabolism and LIPOGENESIS. Two major isoforms of the protein exist due to ALTERNATIVE SPLICING.
, SREBP1-C is an isoform of sterol regulatory element binding protein 1 that is a weak activator of GENETIC TRANSCRIPTION. It is the predominant form in LIVER and ADIPOCYTES, and it mediates INSULIN induced FATTY ACIDS synthesis.
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Sterol Regulatory Element Binding Protein 2
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D051782 |
[A sterol regulatory element binding protein that regulates GENES involved in CHOLESTEROL synthesis and uptake.
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Sterol Regulatory Element Binding Proteins
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D051779 |
[Sterol regulatory element binding proteins are basic helix-loop-helix leucine zipper transcription factors that bind the sterol regulatory element TCACNCCAC. They are synthesized as precursors that are threaded into the MEMBRANES of the ENDOPLASMIC RETICULUM.
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Sterols
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D013261 |
[Steroids with a hydroxyl group at C-3 and most of the skeleton of cholestane. Additional carbon atoms may be present in the side chain. (IUPAC Steroid Nomenclature, 1987)
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Steryl-Sulfatase
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D043266 |
[An arylsulfatase with high specificity towards sulfated steroids. Defects in this enzyme are the cause of ICHTHYOSIS, X-LINKED.
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Stethoscopes
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D019023 |
[Instruments intended to detect and study sound produced by the heart, lungs, or other parts of the body. (from UMDNS, 1999)
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Stevens-Johnson Syndrome
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D013262 |
[An exfoliative disease of skin seen primarily in adults and characterized by flaccid bullae and spreading erythema so that the skin has the appearance of being scalded. It results primarily from a toxic reaction to various drugs, but occasionally occurs as a result of infection, neoplastic conditions, or other exposure.
, Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
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Stevia
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D036625 |
[A plant genus of the family ASTERACEAE. Members contain stevioside and other sweet diterpene glycosides. The leaf is used for sweetening (SWEETENING AGENTS).
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Stichopus
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D047528 |
[A genus of very large, epibenthic SEA CUCUMBERS in the family Stichopodidae, commercially harvested in Southeast Asia for food.
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Stiff-Person Syndrome
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D016750 |
[A condition characterized by persistent spasms (SPASM) involving multiple muscles, primarily in the lower limbs and trunk. The illness tends to occur in the fourth to sixth decade of life, presenting with intermittent spasms that become continuous. Minor sensory stimuli, such as noise and light touch, precipitate severe spasms. Spasms do not occur during sleep and only rarely involve cranial muscles. Respiration may become impaired in advanced cases. (Adams et al., Principles of Neurology, 6th ed, p1492; Neurology 1998 Jul;51(1):85-93)
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Stifle
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D013264 |
[In horses, cattle, and other quadrupeds, the joint between the femur and the tibia, corresponding to the human knee.
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Stigmasterol
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D013265 |
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Stigmatella
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D020597 |
[A genus of the MYXOCOCCALES having vegetative cells which are straight rods with tapered ends and myxospores which are short and somewhat crooked. Fruiting bodies consist of spherical, ovoid, or club-shaped sporangioles on stalks. (From Bergey's Manual of Determinative Bacteriology, 9th ed)
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Stigmatella aurantiaca
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D020606 |
[A species of STIGMATELLA usually isolated from rotting wood. (From Bergey's Manual of Determinative Bacteriology, 9th ed)
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