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Sterilization Reversal
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D013243 |
[Procedures to reverse the effect of REPRODUCTIVE STERILIZATION and to regain fertility. Reversal procedures include those used to restore the flow in the FALLOPIAN TUBE or the VAS DEFERENS.
] |
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Sterilization, Involuntary
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D013244 |
[Interference of a person's reproductive ability without the consent of the person or guardian.
] |
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Sterilization, Reproductive
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D013245 |
[Procedures to block or remove all or part of the genital tract for the purpose of rendering individuals sterile, incapable of reproduction. Surgical sterilization procedures are the most commonly used. There are also sterilization procedures involving chemical or physical means.
] |
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Sterilization, Tubal
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D013246 |
[A fimbriectomy technique that consists of excising the distal tube and fimbriae, and ligating the cut ends of the tube with silk sutures.
, Procedures that render the female sterile by interrupting the flow in the FALLOPIAN TUBE. These procedures generally are surgical, and may also use chemicals or physical means.
, A knuckle of FALLOPIAN TUBE is ligated with absorbable suture, then a small segment is excised.
] |
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Sternoclavicular Joint
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D013247 |
[A double gliding joint formed by the CLAVICLE, superior and lateral parts of the manubrium sterni at the clavicular notch, and the cartilage of the first rib.
] |
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Sternocostal Joints
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D013248 |
[An articulation where the costal cartilage of each rib fit with slight concavities along the lateral borders of the STERNUM.
] |
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Sternotomy
|
D056346 |
[Making an incision in the STERNUM.
, Incision through the midline of the STERNUM.
] |
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Sternum
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D013249 |
[A long, narrow, and flat bone commonly known as BREASTBONE occurring in the midsection of the anterior thoracic segment or chest region, which stabilizes the rib cage and serves as the point of origin for several muscles that move the arms, head, and neck.
] |
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Steroid 11-beta-Hydroxylase
|
D013252 |
[A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11B1 gene, is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).
] |
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Steroid 12-alpha-Hydroxylase
|
D013253 |
[A liver microsomal cytochrome P450 enzyme that catalyzes the 12-alpha-hydroxylation of a broad spectrum of sterols in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP8B1gene, converts 7-alpha-hydroxy-4-cholesten-3-one to 7-alpha-12-alpha-dihydroxy-4-cholesten-3-one and is required in the synthesis of BILE ACIDS from cholesterol.
] |
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Steroid 16-alpha-Hydroxylase
|
D039181 |
[A liver microsomal cytochrome P450 enzyme that catalyzes the 16-alpha-hydroxylation of a broad spectrum of steroids, fatty acids, and xenobiotics in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme is encoded by a number of genes from several CYP2 subfamilies.
] |
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Steroid 17-alpha-Hydroxylase
|
D013254 |
[A microsomal cytochrome P450 enzyme that catalyzes the 17-alpha-hydroxylation of progesterone or pregnenolone and subsequent cleavage of the residual two carbons at C17 in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP17 gene, generates precursors for glucocorticoid, androgen, and estrogen synthesis. Defects in CYP17 gene cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL) and abnormal sexual differentiation.
] |
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Steroid 21-Hydroxylase
|
D013255 |
[An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP21 gene, converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).
] |
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Steroid Hydroxylases
|
D013250 |
[Cytochrome P-450 monooxygenases (MIXED FUNCTION OXYGENASES) that are important in steroid biosynthesis and metabolism.
] |
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Steroid Isomerases
|
D013251 |
[Enzymes that catalyze the transposition of double bond(s) in a steroid molecule. EC 5.3.3.
] |
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Steroid Metabolism, Inborn Errors
|
D043202 |
[Errors in metabolic processing of STEROIDS resulting from inborn genetic mutations that are inherited or acquired in utero.
] |
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Steroid Synthesis Inhibitors
|
D065088 |
[Compounds that bind to and inhibit enzymes involved in the synthesis of STEROIDS.
] |
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Steroidogenic Factor 1
|
D054339 |
[A transcription factor and member of the nuclear receptor family NR5 that is expressed throughout the adrenal and reproductive axes during development. It plays an important role in sexual differentiation, formation of primary steroidogenic tissues, and their functions in post-natal and adult life. It regulates the expression of key steroidogenic enzymes.
] |
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Steroids
|
D013256 |
[A group of polycyclic compounds closely related biochemically to TERPENES. They include cholesterol, numerous hormones, precursors of certain vitamins, bile acids, alcohols (STEROLS), and certain natural drugs and poisons. Steroids have a common nucleus, a fused, reduced 17-carbon atom ring system, cyclopentanoperhydrophenanthrene. Most steroids also have two methyl groups and an aliphatic side-chain attached to the nucleus. (From Hawley's Condensed Chemical Dictionary, 11th ed)
] |
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Steroids, Brominated
|
D013257 |
[Steroids which are substituted with one or more bromine atoms in any position.
] |
