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Receptor, Fibroblast Growth Factor, Type 3
|
D051498 |
[A fibroblast growth factor receptor that regulates CHONDROCYTE growth and CELL DIFFERENTIATION. Mutations in the gene for fibroblast growth factor receptor 3 have been associated with ACHONDROPLASIA; THANATOPHORIC DYSPLASIA and NEOPLASTIC CELL TRANSFORMATION.
] |
|
Receptor, Fibroblast Growth Factor, Type 4
|
D051499 |
[A fibroblast growth factor receptor that is mainly expressed in LUNG; KIDNEY; PANCREAS; and SPLEEN. It also plays an important role in SKELETAL MUSCLE development and can contribute to NEOPLASTIC CELL TRANSFORMATION.
] |
|
Receptor, Fibroblast Growth Factor, Type 5
|
D051500 |
[The most divergent of the known fibroblast growth factor receptors. It does not contain an intracellular TYROSINE KINASE domain and has been shown to interact with FIBROBLAST GROWTH FACTOR 2. Fibroblast growth factor receptor 5 is found primarily in skeletal tissue.
] |
|
Receptor, Galanin, Type 1
|
D044091 |
[The most abundant galanin receptor subtype. It displays a high affinity for the full-length form of GALANIN.
] |
|
Receptor, Galanin, Type 2
|
D044092 |
[A galanin receptor subtype with broad specificity for full length GALANIN, galanin peptide fragments and GALANIN-LIKE PEPTIDE.
] |
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Receptor, Galanin, Type 3
|
D044093 |
[A galanin receptor subtype with high affinity for GALANIN-LIKE PEPTIDE and low affinity for full length GALANIN and galanin peptide fragments.
] |
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Receptor, IGF Type 1
|
D017526 |
[A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Although commonly referred to as the IGF-I receptor, it binds both IGF-I and IGF-II with high affinity. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The beta subunit contains an intrinsic tyrosine kinase domain.
] |
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Receptor, IGF Type 2
|
D017527 |
[A receptor that is specific for IGF-II and mannose-6-phosphate. The receptor is a 250-kDa single chain polypeptide which is unrelated in structure to the type 1 IGF receptor (RECEPTOR, IGF TYPE 1) and does not have a tyrosine kinase domain.
] |
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Receptor, Insulin
|
D011972 |
[A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic TYROSINE KINASE domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the liver, muscle, and ADIPOSE TISSUE.
] |
|
Receptor, Interferon alpha-beta
|
D053633 |
[A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTERFERON-BETA. It is composed of two subunits referred to as IFNAR1 and IFNAR2. The IFNAR2 subunit is believed to serve as the ligand-binding chain; however both chains are required for signal transduction. The interferon alpha-beta receptor signals through the action of JANUS KINASES such as the TYK2 KINASE.
, A shortened cytoplasmic domain variant of the IFNAR2 chain.
, The full-length variant of the IFNAR2 chain.
] |
|
Receptor, Macrophage Colony-Stimulating Factor
|
D016186 |
[A receptor for MACROPHAGE COLONY-STIMULATING FACTOR encoded by the c-fms proto-oncogene (GENES, FMS). It contains an intrinsic protein-tyrosine kinase activity. When activated the receptor undergoes autophosphorylation, phosphorylation of down-stream signaling molecules and rapid down-regulation.
] |
|
Receptor, Melanocortin, Type 1
|
D044102 |
[A melanocortin receptor subtype found primarily in MELANOCYTES. It shows specificity for ALPHA-MSH and ADRENOCORTICOTROPIC HORMONE. Loss of function mutations of the type 1 melanocortin receptor account for the majority of red hair and fair skin recessive traits in human.
] |
|
Receptor, Melanocortin, Type 2
|
D044103 |
[A melanocortin receptor subtype found primarily in the ADRENAL CORTEX. It shows specificity for ADRENOCORTICOTROPIC HORMONE.
] |
|
Receptor, Melanocortin, Type 3
|
D044104 |
[A melanocortin receptor subtype found primarily in BRAIN. It shows specificity for ALPHA-MSH; BETA-MSH; GAMMA-MSH and ADRENOCORTICOTROPIC HORMONE.
] |
|
Receptor, Melanocortin, Type 4
|
D044105 |
[A melanocortin receptor subtype found primarily in BRAIN. It shows specificity for ALPHA-MSH; BETA-MSH and ADRENOCORTICOTROPIC HORMONE.
] |
|
Receptor, Melatonin, MT1
|
D044122 |
[A melatonin receptor subtype that is primarily found in the HYPOTHALAMUS and in the KIDNEY.
] |
|
Receptor, Melatonin, MT2
|
D044123 |
[A melatonin receptor subtype primarily found expressed in the BRAIN and RETINA.
] |
|
Receptor, Metabotropic Glutamate 5
|
D064529 |
[A type I G protein-coupled receptor mostly expressed post-synaptic pyramidal cells of the cortex and CENTRAL NERVOUS SYSTEM.
] |
|
Receptor, Muscarinic M1
|
D043643 |
[A specific subtype of muscarinic receptor that has a high affinity for the drug PIRENZEPINE. It is found in the peripheral GANGLIA where it signals a variety of physiological functions such as GASTRIC ACID secretion and BRONCHOCONSTRICTION. This subtype of muscarinic receptor is also found in neuronal tissues including the CEREBRAL CORTEX and HIPPOCAMPUS where it mediates the process of MEMORY and LEARNING.
] |
|
Receptor, Muscarinic M2
|
D043585 |
[A specific subtype of muscarinic receptor found in the lower BRAIN, the HEART and in SMOOTH MUSCLE-containing organs. Although present in smooth muscle the M2 muscarinic receptor appears not to be involved in contractile responses.
] |
