All individuals in MeSH

Label Id Description
Protein Transport D021381 [The process by which proteins are moved into or through the cell membranes by protein translocator molecules that recognize their signal peptides. , A mechanism which uses selective gates to actively transport proteins from one cellular compartment to another. , The process of moving proteins from one cellular compartment (including extracellular) to another by various sorting and transport mechanisms such as gated transport, protein translocation, and vesicular transport. , The process of the secretory and endocytic pathways, in which proteins are loaded into transport vesicles and then delivered to a different cellular compartments by the process of exocytosis. ]
Protein Tyrosine Phosphatase, Non-Receptor Type 1 D054562 [A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting motifs; an N-terminal motif specific for the INSULIN RECEPTOR, and a C-terminal motif specific for the SH3 domain containing proteins. This subtype includes a hydrophobic domain which localizes it to the ENDOPLASMIC RETICULUM. ]
Protein Tyrosine Phosphatase, Non-Receptor Type 11 D054592 [A subtype of non-receptor protein tyrosine phosphatases that contain two SRC HOMOLOGY DOMAINS. Mutations in the gene for protein tyrosine phosphatase, non-receptor type 11 are associated with NOONAN SYNDROME. ]
Protein Tyrosine Phosphatase, Non-Receptor Type 12 D054594 [A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of a N-terminal catalytic domain and a large C-terminal domain that is enriched in PROLINE, GLUTAMIC ACID, SERINE, and THREONINE residues (PEST sequences). The phosphatase subtype is ubiquitously expressed and implicated in the regulation of a variety of biological processes such as CELL MOVEMENT; CYTOKINESIS; focal adhesion disassembly; and LYMPHOCYTE ACTIVATION. ]
Protein Tyrosine Phosphatase, Non-Receptor Type 13 D054595 [A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an amino-terminal FERM domain, an intervening region containing five different PDZ domains, and a carboxyl-terminal phosphatase domain. In addition to playing a role as a regulator of the FAS RECEPTOR activity this subtype interacts via its PDZ and FERM domains with a variety of INTRACELLULAR SIGNALING PROTEINS and CYTOSKELETAL PROTEINS. ]
Protein Tyrosine Phosphatase, Non-Receptor Type 2 D054578 [A subtype of non-receptor protein tyrosine phosphatase that is closely-related to PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1. Alternative splicing of the mRNA for this phosphatase results in the production at two gene products, one of which includes a C-terminal nuclear localization domain that may be involved in the transport of the protein to the CELL NUCLEUS. Although initially referred to as T-cell protein tyrosine phosphatase the expression of this subtype occurs widely. ]
Protein Tyrosine Phosphatase, Non-Receptor Type 22 D054596 [A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an N-terminal catalytic domain and a C-terminal PROLINE-rich domain. The phosphatase subtype is predominantly expressed in LYMPHOCYTES and plays a key role in the inhibition of downstream T-LYMPHOCYTE activation. Polymorphisms in the gene that encodes this phosphatase subtype are associated with a variety of AUTOIMMUNE DISEASES. , An alternatively spliced variant of tyrosine protein phosphatase, non-receptor type 22. ]
Protein Tyrosine Phosphatase, Non-Receptor Type 3 D054589 [A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an amino-terminal FERM domain, an intervening region containing one or more PDZ domains, and a carboxyl-terminal phosphatase domain. Expression of this phosphatase subtype has been observed in BONE MARROW; fetal LIVER; LYMPH NODES; and T LYMPHOCYTES. ]
Protein Tyrosine Phosphatase, Non-Receptor Type 4 D054590 [A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an amino-terminal FERM domain, an intervening region containing one or more PDZ domains, and a carboxyl-terminal phosphatase domain. The subtype was originally identified in a cell line derived from MEGAKARYOCYTES. ]
Protein Tyrosine Phosphatase, Non-Receptor Type 6 D053824 [A Src-homology domain-containing protein tyrosine phosphatase found in the CYTOSOL of hematopoietic cells. It plays a role in signal transduction by dephosphorylating signaling proteins that are activated or inactivated by PROTEIN-TYROSINE KINASES. ]
Protein Tyrosine Phosphatases D017027 [An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis. ]
Protein Tyrosine Phosphatases, Non-Receptor D054558 [A subcategory of protein tyrosine phosphatases that occur in the CYTOPLASM. Many of the proteins in this category play a role in intracellular signal transduction. ]
Protein Unfolding D058767 [Conformational transitions of the shape of a protein to various unfolded states. ]
Protein-Arginine Deiminase Type 1 D000080062 [A peptidylarginine deiminase isoenzyme. It is a post-translational modification enzyme that catalyzes the conversion of protein-bound ARGININE residues to CITRULLINE residues in a CALCIUM ion-dependent manner. It functions within the epidermis, targeting INTERMEDIATE FILAMENTS; KERATINS; and filaggrin for CITRULLINATION to promote epidermal cornification. ]
Protein-Arginine Deiminase Type 2 D000080064 [A widely expressed isoenzyme of peptidylarginine deiminase, a post-translational modification enzyme that catalyzes the conversion of protein-bound ARGININE residues to CITRULLINE residues in a CALCIUM ion-dependent manner. ]
Protein-Arginine Deiminase Type 3 D000080063 [A post-translational enzyme that catalyzes the conversion of protein bound arginine residues to CITRULLINE residues in a CALCIUM ion-dependent manner. PADI3 is a peptidylarginine deiminase isoenzyme expressed in epidermal tissue. ]
Protein-Arginine Deiminase Type 4 D000080002 [A histone modification enzyme, which converts both ARGININE and monomethyl-arginine to CITRULLINE. It is one of several protein-arginine deiminase isoenzymes. It is a gene regulator involved in APOPTOSIS and CELL DIFFERENTIATION and a potential therapeutic target for the treatment of a variety of diseases. ]
Protein-Arginine Deiminase Type 6 D000080065 [A peptidylarginine deiminase isoenzyme mainly expressed in egg and embryo tissues. It is a post-translational modification enzyme that catalyzes the conversion of protein-bound ARGININE residues to CITRULLINE residues in a CALCIUM ion-dependent manner. ]
Protein-Arginine Deiminases D000076342 [A family of ENZYMES that, in the presence of calcium ion, converts ARGININE to CITRULLINE in proteins. There are five PAD isotypes in mammals. In humans: they include PAD1, 2, 3, 4 and 6. They are encoded by five paralogous genes named PADI and clustered on human chromosome 1. ]
Protein-Arginine N-Methyltransferases D011484 [Enzymes that catalyze the methylation of arginine residues of proteins to yield N-mono- and N,N-dimethylarginine. This enzyme is found in many organs, primarily brain and spleen. ]