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Promyelocytic Leukemia Zinc Finger Protein
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D000075722 |
[A Kruppel-type transcription factor consisting of an N-terminal BTB DOMAIN and nine CYS2-HIS2 ZINC FINGERS. It localizes to the nucleus and regulates cell cycle progression and gene expression for tissue development and homeostasis; it may also function as an epigenetic regulator through its interactions with HISTONE DEACETYLASE. Genetic rearrangements involving the ZBTB16 gene are associated with ACUTE PROMYELOCYTIC LEUKEMIA.
] |
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Pronase
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D011402 |
[A proteolytic enzyme obtained from Streptomyces griseus.
] |
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Pronation
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D011403 |
[Applies to movements of the forearm in turning the palm backward or downward. When referring to the foot, a combination of eversion and abduction movements in the tarsal and metatarsal joints (turning the foot up and in toward the midline of the body).
] |
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Prone Position
|
D016684 |
[The posture of an individual lying face down.
] |
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Pronephros
|
D060910 |
[The primordial kidney that develops from the INTERMEDIATE MESODERM in the embryos of vertebrates, and is succeeded by the MESONEPHROS. In higher vertebrates and humans, the pronephros is a vestigial and transient structure.
] |
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Proof of Concept Study
|
D000075082 |
[An empirical investigation which pertains to the development of prototypes or models that demonstrate the feasibility of novel concepts, ideas, principles, schema or their practical application.
] |
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Propafenone
|
D011405 |
[An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
] |
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Propaganda
|
D011406 |
[The deliberate attempt to influence attitudes and beliefs for furthering one's cause or damaging an opponent's cause.
] |
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Propane
|
D011407 |
[A three carbon alkane with the formula H3CCH2CH3.
] |
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Propanediol Dehydratase
|
D011408 |
[An enzyme that catalyzes the dehydration of 1,2-propanediol to propionaldehyde. EC 4.2.1.28.
] |
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Propanidid
|
D011410 |
[An intravenous anesthetic that has been used for rapid induction of anesthesia and for maintenance of anesthesia of short duration. (From Martindale, The Extra Pharmacopoeia, 30th ed, p918)
] |
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Propanil
|
D011411 |
[A chlorinated anilide that is used as an herbicide.
] |
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Propanolamines
|
D011412 |
[AMINO ALCOHOLS containing the propanolamine (NH2CH2CHOHCH2) group and its derivatives.
] |
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Propanols
|
D020005 |
[Isomeric forms and derivatives of PROPANOL (C3H7OH).
] |
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Propantheline
|
D011413 |
[A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking.
] |
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Propensity Score
|
D057216 |
[Conditional probability of exposure to a treatment given observed covariates.
] |
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Properdin
|
D011414 |
[A 53-kDa protein that is a positive regulator of the alternate pathway of complement activation (COMPLEMENT ACTIVATION PATHWAY, ALTERNATIVE). It stabilizes the ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb) and protects it from rapid inactivation, thus facilitating the cascade of COMPLEMENT ACTIVATION and the formation of MEMBRANE ATTACK COMPLEX. Individuals with mutation in the PFC gene exhibit properdin deficiency and have a high susceptibility to infections.
] |
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Prophages
|
D039002 |
[Genomes of temperate BACTERIOPHAGES integrated into the DNA of their bacterial host cell. The prophages can be duplicated for many cell generations until some stimulus induces its activation and virulence.
] |
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Prophase
|
D011418 |
[The first phase of cell nucleus division, in which the CHROMOSOMES become visible, the CELL NUCLEUS starts to lose its identity, the SPINDLE APPARATUS appears, and the CENTRIOLES migrate toward opposite poles.
] |
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Prophylactic Mastectomy
|
D000072036 |
[Surgical removal of one or both breasts to prevent or reduce the risk of developing breast cancer in persons who may be predisposed.
] |
