A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by inactivating MITOGEN-ACTIVATED PROTEIN KINASES. It has specificity for EXTRACELLULAR SIGNAL-REGULATED MAP KINASES and is primarily localized to the CYTOSOL.

Synonyms: Mitogen Activated Protein Kinase Phosphatase 3 Phosphatase, MKP3 Mitogen-Activated Protein Kinase Phosphatase 3 MKP-3 Phosphatase MKP3 Phosphatase Phosphatase, MKP-3 MAP Kinase Phosphatase 3 EC 3.1.3.48 Dual Specificity Protein Phosphatase 6 MKP 3 Phosphatase Dual Specificity Phosphatase 6