A family of thioltransferases that contain two active site CYSTEINE residues, which either form a disulfide (oxidized form) or a dithiol (reduced form). They function as an electron carrier in the GLUTHIONE-dependent synthesis of deoxyribonucleotides by RIBONUCLEOTIDE REDUCTASES and may play a role in the deglutathionylation of protein thiols. The oxidized forms of glutaredoxins are directly reduced by the GLUTATHIONE.

Synonyms: 0 Glutaredoxin 2 Glutaredoxin 3 Thioltransferase-1 Glutaredoxin 5 Glutaredoxins Glutaredoxin 1 Glutaredoxin TTase-1 Thioltransferase TTase 1 Thioltransferase 1