A family of ubiquitously-expressed peroxidases that play a role in the reduction of a broad spectrum of PEROXIDES like HYDROGEN PEROXIDE; LIPID PEROXIDES and peroxinitrite. They are found in a wide range of organisms, such as BACTERIA; PLANTS; and MAMMALS. The enzyme requires the presence of a thiol-containing intermediate such as THIOREDOXIN as a reducing cofactor.

Synonyms: Peroxiredoxin Hydroperoxide Reductase, Alkyl Peroxiredoxin V Thiol Specific Antioxidant Protein Thiol-Specific Antioxidant Protein Peroxiredoxin II Peroxidoxin Protector Protein (Mixed-Function Oxidase Systems) EC 1.11.1.15 Peroxiredoxin IV Peroxiredoxin-4 Thioredoxin Peroxidase PMP20 Peroxiredoxin I Thioredoxin-Dependent Peroxide Reductase 1 Thioredoxin-Dependent Peroxide Reductase 2 Thioredoxin Peroxidase 1 Thioredoxin Peroxidase 2 Thioredoxin Dependent Peroxide Reductase 1 Alkylhydroperoxide Reductase Thioredoxin Peroxidase Peroxiredoxin 4 Peroxiredoxin 5 Alkyl Hydroperoxide Reductase C Alkyl Hydroperoxide Reductase D Peroxiredoxins Peroxiredoxin 2 Alkyl Hydroperoxide Reductase Peroxiredoxin 1 Thioredoxin Dependent Peroxide Reductase 2