|
Nuclear Receptor Subfamily 2, Group C, Member 2
|
D057125 |
[An orphan nuclear receptor that has specificity for hormone response elements found in the promoters of target genes. It binds DNA either as a homodimer or as heterodimer with the closely-related orphan nuclear receptor NUCLEAR RECEPTOR SUBFAMILY 2, GROUP C, MEMBER 1. The protein was originally identified as a TESTES-specific protein and is involved in the regulation of variety of cellular processes, including CELL DIFFERENTIATION; CELL PROLIFERATION; and APOPTOSIS.
] |
|
Nuclear Receptor Subfamily 4, Group A, Member 1
|
D057105 |
[An orphan nuclear receptor that is closely related to members of the thyroid-steroid receptor gene family. It was originally identified in NERVE CELLS and may play a role in mediation of NERVE GROWTH FACTOR-induced CELL DIFFERENTIATION. However, several other functions have been attributed to this protein including the positive and negative regulation of APOPTOSIS.
] |
|
Nuclear Receptor Subfamily 4, Group A, Member 2
|
D057126 |
[An orphan nuclear receptor that is found at high levels in BRAIN tissue. The protein is believed to play a role in development and maintenance of NEURONS, particularly dopaminergic neurons.
] |
|
Nuclear Receptor Subfamily 4, Group A, Member 3
|
D057106 |
[An orphan nuclear receptor that is closely related to members of the thyroid-steroid receptor family. It was originally identified in NERVE CELLS, however it may play regulatory roles in a variety of other tissues.
] |
|
Nuclear Receptor Subfamily 6, Group A, Member 1
|
D057136 |
[An orphan nuclear receptor expressed mainly in the GERM CELLS of GONADS. It functions as a transcription factor that binds to a direct repeat of the sequence AGGTCA and may play a role in the regulation of EMBRYOGENESIS and germ cell differentiation.
] |
|
Nuclear Respiratory Factor 1
|
D051266 |
[A transcription factor that controls the expression of variety of proteins including CYTOCHROME C and 5-AMINOLEVULINATE SYNTHETASE. It plays an important role in maintenance of the RESPIRATORY CHAIN of MITOCHONDRIA.
] |
|
Nuclear Respiratory Factors
|
D051264 |
[A family of transcription factors that control expression of a variety of nuclear GENES encoding proteins that function in the RESPIRATORY CHAIN of the MITOCHONDRIA.
] |
|
Nuclear Transfer Techniques
|
D053652 |
[Methods of implanting a CELL NUCLEUS from a donor cell into an enucleated acceptor cell.
] |
|
Nuclear Warfare
|
D009689 |
[Warfare involving the use of NUCLEAR WEAPONS.
] |
|
Nuclear Weapons
|
D054043 |
[A weapon that derives its destructive force from nuclear fission and/or fusion.
, Weapons that contain EXPLOSIVES and RADIOACTIVE POLLUTANTS.
] |
|
Nuclease Protection Assays
|
D023282 |
[Techniques for measuring specific nucleic acid interaction with another nucleic acid or with a protein by digestion of the non-interacting nucleic acid by various nucleases. After all non-interacting regions are eliminated by nuclease digestion, the protected nucleic acid that remains is analyzed. DNA FOOTPRINTING utilizes this technique to analyze the DNA contact sites of DNA-BINDING PROTEINS.
] |
|
Nucleic Acid Amplification Techniques
|
D021141 |
[Laboratory techniques that involve the in-vitro synthesis of many copies of DNA or RNA from one original template.
, Diagnostic nucleic acid amplification procedures used to test for the presence of an infectious agent or a specific ALLELE or MUTATION.
] |
|
Nucleic Acid Conformation
|
D009690 |
[The spatial arrangement of the atoms of a nucleic acid or polynucleotide that results in its characteristic 3-dimensional shape.
] |
|
Nucleic Acid Denaturation
|
D009691 |
[Disruption of the secondary structure of nucleic acids by heat, extreme pH or chemical treatment. Double strand DNA is "melted" by dissociation of the non-covalent hydrogen bonds and hydrophobic interactions. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible.
] |
|
Nucleic Acid Heteroduplexes
|
D009692 |
[Double-stranded nucleic acid molecules (DNA-DNA or DNA-RNA) which contain regions of nucleotide mismatches (non-complementary). In vivo, these heteroduplexes can result from mutation or genetic recombination; in vitro, they are formed by nucleic acid hybridization. Electron microscopic analysis of the resulting heteroduplexes facilitates the mapping of regions of base sequence homology of nucleic acids.
] |
|
Nucleic Acid Hybridization
|
D009693 |
[Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)
] |
|
Nucleic Acid Precursors
|
D009694 |
[Use for nucleic acid precursors in general or for which there is no specific heading.
] |
|
Nucleic Acid Probes
|
D015341 |
[Nucleic acid which complements a specific mRNA or DNA molecule, or fragment thereof; used for hybridization studies in order to identify microorganisms and for genetic studies.
] |
|
Nucleic Acid Renaturation
|
D009695 |
[The reformation of all, or part of, the native conformation of a nucleic acid molecule after the molecule has undergone denaturation.
] |
|
Nucleic Acid Synthesis Inhibitors
|
D019384 |
[Compounds that inhibit cell production of DNA or RNA.
] |
