|
Nictitating Membrane
|
D009541 |
[A fold of the mucous membrane of the CONJUNCTIVA in many animals. At rest, it is hidden in the medial canthus. It can extend to cover part or all of the cornea to help clean the CORNEA.
] |
|
Nidovirales
|
D028381 |
[An order comprising three families of eukaryotic viruses possessing linear, nonsegmented, positive sense RNA genomes. The families are Mesoniviridae; CORONAVIRIDAE; ARTERIVIRIDAE; and RONIVIRIDAE.
] |
|
Nidovirales Infections
|
D030341 |
[Infections with viruses of the order NIDOVIRALES. The concept includes ARTERIVIRUS INFECTIONS and CORONAVIRIDAE INFECTIONS.
] |
|
Niemann-Pick C1 Protein
|
D000077296 |
[A transmembrane intracellular lipid transporter that helps trafficking lipids, particularly cholesterol, from late endosome/lysosome to the ER and plasma membrane. It may also play a role in other cellular cholesterol homeostasis and is an endosomal entry receptor for filoviruses including EBOLAVIRUS. Mutations in the NPC1 are associated with type C NIEMANN-PICK DISEASE.
] |
|
Niemann-Pick Disease, Type A
|
D052536 |
[The classic infantile form of Niemann-Pick Disease, caused by mutation in SPHINGOMYELIN PHOSPHODIESTERASE. It is characterized by accumulation of SPHINGOMYELINS in the cells of the MONONUCLEAR PHAGOCYTE SYSTEM and other cell throughout the body leading to cell death. Clinical signs include JAUNDICE, hepatosplenomegaly, and severe brain damage.
] |
|
Niemann-Pick Disease, Type B
|
D052537 |
[An allelic disorder of TYPE A NIEMANN-PICK DISEASE, a late-onset form. It is also caused by mutation in SPHINGOMYELIN PHOSPHODIESTERASE but clinical signs involve only visceral organs (non-neuropathic type).
] |
|
Niemann-Pick Disease, Type C
|
D052556 |
[An autosomal recessive lipid storage disorder that is characterized by accumulation of CHOLESTEROL and SPHINGOMYELINS in cells of the VISCERA and the CENTRAL NERVOUS SYSTEM. Type C (or C1) and type D are allelic disorders caused by mutation of the NPC1 gene, which encodes a protein that mediates intracellular cholesterol transport from LYSOSOMES. Clinical signs include hepatosplenomegaly and chronic neurological symptoms. Type D is a variant in people with a Nova Scotia ancestry.
] |
|
Niemann-Pick Diseases
|
D009542 |
[A group of autosomal recessive disorders in which harmful quantities of lipids accumulate in the viscera and the central nervous system. They can be caused by deficiencies of enzyme activities (SPHINGOMYELIN PHOSPHODIESTERASE) or defects in intracellular transport, resulting in the accumulation of SPHINGOMYELINS and CHOLESTEROL. There are various subtypes based on their clinical and genetic differences.
] |
|
Nifedipine
|
D009543 |
[A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
] |
|
Niflumic Acid
|
D009544 |
[An analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.
] |
|
Nifuratel
|
D009545 |
[Local antiprotozoal and antifungal agent that may also be given orally.
] |
|
Nifurtimox
|
D009547 |
[A nitrofuran thiazine that has been used against TRYPANOSOMIASIS.
] |
|
Nigella
|
D031844 |
[A plant genus of the family RANUNCULACEAE.
] |
|
Nigella damascena
|
D031861 |
[A plant genus of the family RANUNCULACEAE. The name is similar to giant fennel (FERULA), true fennel (FOENICULUM), and dog fennel (ANTHEMIS).
] |
|
Nigella sativa
|
D031881 |
[A plant genus of the family RANUNCULACEAE that contains alpha-hederin, a triterpene saponin in the seeds, and is the source of black seed oil.
] |
|
Niger
|
D009548 |
[A republic in western Africa, north of NIGERIA and west of CHAD. Its capital is Niamey.
] |
|
Nigeria
|
D009549 |
[A republic in western Africa, south of NIGER between BENIN and CAMEROON. Its capital is Abuja.
] |
|
Nigericin
|
D009550 |
[A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck Index, 11th ed)
] |
|
Night Blindness
|
D009755 |
[Failure or imperfection of vision at night or in dim light, with good vision only on bright days. (Dorland, 27th ed)
] |
|
Night Care
|
D009551 |
[Institutional night care of patients.
] |
