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Nervous System Diseases
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D009422 |
[Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.
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Nervous System Malformations
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D009421 |
[Structural abnormalities of the central or peripheral nervous system resulting primarily from defects of embryogenesis.
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Nervous System Neoplasms
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D009423 |
[Benign and malignant neoplastic processes arising from or involving components of the central, peripheral, and autonomic nervous systems, cranial nerves, and meninges. Included in this category are primary and metastatic nervous system neoplasms.
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Nervous System Physiological Phenomena
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D009424 |
[Biological actions and events that constitute the functions of the NERVOUS SYSTEM.
, Characteristic properties and processes of the NERVOUS SYSTEM as a whole or with reference to the peripheral or the CENTRAL NERVOUS SYSTEM.
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Nesidioblastosis
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D046768 |
[An inherited autosomal recessive syndrome characterized by the disorganized formation of new islets in the PANCREAS and CONGENITAL HYPERINSULINISM. It is due to focal hyperplasia of pancreatic ISLET CELLS budding off from the ductal structures and forming new islets of Langerhans. Mutations in the islet cells involve the potassium channel gene KCNJ11 or the ATP-binding cassette transporter gene ABCC8, both on CHROMOSOME 11.
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Nested Genes
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D032041 |
[Genes whose entire sequences are contained within other genes.
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Nestin
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D064231 |
[A type VI intermediate filament protein expressed mostly in nerve cells where it is associated with the survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
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Nesting Behavior
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D009425 |
[Animal behavior associated with the nest; includes construction, effects of size and material; behavior of the adult during the nesting period and the effect of the nest on the behavior of the young.
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Netherlands
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D009426 |
[Country located in EUROPE. It is bordered by the NORTH SEA, BELGIUM, and GERMANY. Constituent areas are Aruba, Curacao, and Sint Maarten, formerly included in the NETHERLANDS ANTILLES.
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Netherlands Antilles
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D009427 |
[Former Netherlands overseas territory in the Lesser Antilles in the West Indies. It had included the islands of Aruba, Bonaire, Curacao, Saba, St. Eustatius, and the southern part of St. Martin. The Netherlands Antilles dissolved on October 10, 2010.
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Netherton Syndrome
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D056770 |
[Rare autosomal recessive disease with variable expressions. Clinical features of the disease include variable ICHTHYOSIFORM ERYTHRODERMA, CONGENITAL; bamboo hair (trichorrhexis invaginata); and ATOPIC DERMATITIS. The disease is caused by mutations in the SPINK5 gene.
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Netilmicin
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D009428 |
[Semisynthetic 1-N-ethyl derivative of SISOMYCIN, an aminoglycoside antibiotic with action similar to gentamicin, but less ear and kidney toxicity.
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Netrin Receptors
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D000075386 |
[Cell surface receptors that bind NETRINS. They typically contain both IMMUNOGLOBULIN DOMAINS and FIBRONECTIN TYPE III DOMAINS and function to mediate CELL MIGRATION and AXON GUIDANCE.
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Netrin-1
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D000075388 |
[A netrin that binds the DCC RECEPTOR or UNC5 receptors, resulting respectively in axon attraction or repulsion. Its interaction with these receptors also prevents APOPTOSIS; it may function as a tumor suppressor protein.
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Netrins
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D000075385 |
[A family of extracellular proteins that are related structurally to LAMININ. They function as CHEMOTACTIC FACTORS for CELL MIGRATION and AXON GUIDANCE, acting as chemoattractants for some cell types, and as chemorepellents for others.
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Netropsin
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D009429 |
[A basic polypeptide isolated from Streptomyces netropsis. It is cytotoxic and its strong, specific binding to A-T areas of DNA is useful to genetics research.
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Network Meta-Analysis
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D000071076 |
[Meta-analysis of randomized trials in which estimates of comparative treatment effects are visualized and interpreted from a network of interventions that may or may not have been evaluated directly against each other. Common considerations in network meta-analysis include conceptual and statistical heterogeneity and incoherence.
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Neural Analyzers
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D009430 |
[A term used in Eastern European research literature for the functional neural unit that provides the basis for differential sensitivity; the analyzer consists of receptor, afferent nerves, and their central connections. (From Campbell's Psychiatric Dictionary, 8th ed.)
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Neural Cell Adhesion Molecule L1
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D039842 |
[A member of the immunoglobulin superfamily of neuronal cell adhesion molecules that is required for proper nervous system development. Neural cell adhesion molecule L1 consists of six Ig domains, five fibronectin domains, a transmembrane region and an intracellular domain. Two splicing variants are known: a neuronal form that contains a four-amino acid RSLE sequence in the cytoplasmic domain, and a non-neuronal form that lacks the RSLE sequence. Mutations in the L1 gene result in L1 disease. Neural cell adhesion molecule L1 is predominantly expressed during development in neurons and Schwann cells; involved in cell adhesion, neuronal migration, axonal growth and pathfinding, and myelination.
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Neural Cell Adhesion Molecules
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D019006 |
[Cell adhesion molecule involved in a diverse range of contact-mediated interactions among neurons, astrocytes, oligodendrocytes, and myotubes. It is widely but transiently expressed in many tissues early in embryogenesis. Four main isoforms exist, including CD56; (CD56 ANTIGEN); but there are many other variants resulting from alternative splicing and post-translational modifications. (From Pigott & Power, The Adhesion Molecule FactsBook, 1993, pp115-119)
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