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Lysergic Acid Diethylamide
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D008238 |
[Semisynthetic derivative of ergot (Claviceps purpurea). It has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover. It is a potent hallucinogen, but the mechanisms of that effect are not well understood.
] |
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Lysholm Knee Score
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D065466 |
[An instrument used to assess the results of rehabilitation from knee injuries, especially those requiring ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION. It measures recovery of knee joint function based on ACTIVITIES OF DAILY LIVING.
, Method of evaluating knee function following knee injury, treatment, and rehabilitation. It is based on the patient's activity level in work and sports activities.
] |
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Lysine
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D008239 |
[An essential amino acid. It is often added to animal feed.
] |
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Lysine Acetyltransferase 5
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D000074443 |
[A catalytic subunit of the NuA4 histone acetyltransferase complex that functions in transcriptional activation of genes by acetylation of nucleosomal HISTONES H4 and H2A, altering nucleosome-DNA interactions and interaction of the modified histones with other activating transcription factors. It may control gene expression changes associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest; CELL AGING; APOPTOSIS; and DNA REPAIR. It is polyubiquitinated and degraded during HIV-1 infection through its interaction with the viral TAT PROTEIN.
] |
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Lysine Acetyltransferases
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D000070837 |
[Acetyltransferases that can transfer an acyl group to specific LYSINE residues within HISTONES (HISTONE ACETYLTRANSFERASES) and/or non-histone proteins.
] |
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Lysine Carboxypeptidase
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D001121 |
[A metallocarboxypeptidase that removes C-terminal basic amino acid from peptides and proteins, with preference shown for lysine over arginine. It is a plasma zinc enzyme that inactivates bradykinin and anaphylatoxins.
] |
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Lysine-tRNA Ligase
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D008250 |
[An enzyme that activates lysine with its specific transfer RNA. EC 6.1.1.6.
] |
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Lysinoalanine
|
D008241 |
[N(6)-(2-Amino-2-carboxyethyl)-L-lysine. An unusual amino acid, not a dipeptide, which has been found in proteins of cooked foods. It is formed in food that is heated or treated with alkali. Has been implicated in nephrocytomegalia in rats.
] |
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Lysobacter
|
D053528 |
[A genus of gram-negative, rod-shaped, gliding bacteria in the family XANTHOMONADACEAE. Strongly proteolytic, it is involved in lysing a variety of microorganisms.
] |
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Lysogeny
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D008242 |
[The phenomenon by which a temperate phage incorporates itself into the DNA of a bacterial host, establishing a kind of symbiotic relation between PROPHAGE and bacterium which results in the perpetuation of the prophage in all the descendants of the bacterium. Upon induction (VIRUS ACTIVATION) by various agents, such as ultraviolet radiation, the phage is released, which then becomes virulent and lyses the bacterium.
] |
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Lysophosphatidylcholines
|
D008244 |
[Derivatives of PHOSPHATIDYLCHOLINES obtained by their partial hydrolysis which removes one of the fatty acid moieties.
] |
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Lysophospholipase
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D008245 |
[An enzyme that catalyzes the hydrolysis of a single fatty acid ester bond in lysoglycerophosphatidates with the formation of glyceryl phosphatidates and a fatty acid. EC 3.1.1.5.
] |
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Lysophospholipids
|
D008246 |
[Derivatives of PHOSPHATIDIC ACIDS that lack one of its fatty acyl chains due to its hydrolytic removal.
] |
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Lysosomal Storage Diseases
|
D016464 |
[Inborn errors of metabolism characterized by defects in specific lysosomal hydrolases and resulting in intracellular accumulation of unmetabolized substrates.
] |
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Lysosomal Storage Diseases, Nervous System
|
D020140 |
[A group of enzymatic disorders affecting the nervous system and to a variable degree the skeletal system, lymphoreticular system, and other organs. The conditions are marked by an abnormal accumulation of catabolic material within lysosomes.
] |
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Lysosomal-Associated Membrane Protein 1
|
D052118 |
[An abundant lysosomal-associated membrane protein that has been found to shuttle between LYSOSOMES; ENDOSOMES; and the PLASMA MEMBRANE. In PLATELETS and T-LYMPHOCYTES it may play a role in the cellular degranulation process.
] |
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Lysosomal-Associated Membrane Protein 2
|
D052119 |
[An abundant lysosomal-associated membrane protein that has been found to shuttle between LYSOSOMES; ENDOSOMES; and the PLASMA MEMBRANE. Loss of expression of lysosomal-associated membrane protein 2 is associated with GLYCOGEN STORAGE DISEASE TYPE IIB.
] |
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Lysosomal-Associated Membrane Protein 3
|
D059666 |
[A lysosomal-associated membrane glycoprotein that is expressed at high levels in mature DENDRITIC CELLS.
] |
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Lysosome-Associated Membrane Glycoproteins
|
D051907 |
[Ubiquitously expressed integral membrane glycoproteins found in the LYSOSOME.
] |
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Lysosomes
|
D008247 |
[A class of morphologically heterogeneous cytoplasmic particles in animal and plant tissues characterized by their content of hydrolytic enzymes and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured or undergoes MEMBRANE FUSION. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
, Structures formed from the fusion of lysosomes and AUTOPHAGOSOMES that results in the digestion of the autophagosome and its content.
] |
