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Leukemia, Myelomonocytic, Acute
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D015479 |
[A pediatric acute myeloid leukemia involving both myeloid and monocytoid precursors. At least 20% of non-erythroid cells are of monocytic origin.
] |
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Leukemia, Myelomonocytic, Chronic
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D015477 |
[A myelodysplastic-myeloproliferative disease characterized by monocytosis, increased monocytes in the bone marrow, variable degrees of dysplasia, but an absence of immature granulocytes in the blood.
] |
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Leukemia, Myelomonocytic, Juvenile
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D054429 |
[A leukemia affecting young children characterized by SPLENOMEGALY, enlarged lymph nodes, rashes, and hemorrhages. Traditionally classed as a myeloproliferative disease, it is now considered a mixed myeloproliferative-mylelodysplastic disorder.
] |
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Leukemia, Neutrophilic, Chronic
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D015467 |
[A rare myeloproliferative disorder that is characterized by a sustained, mature neutrophilic leukocytosis. No monocytosis, EOSINOPHILIA, or basophilia is present, nor is there a PHILADELPHIA CHROMOSOME or bcr-abl fusion gene (GENES, ABL).
] |
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Leukemia, Plasma Cell
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D007952 |
[A rare, aggressive variant of MULTIPLE MYELOMA characterized by the circulation of excessive PLASMA CELLS in the peripheral blood. It can be a primary manifestation of multiple myeloma or develop as a terminal complication during the disease.
] |
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Leukemia, Prolymphocytic
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D015463 |
[A chronic leukemia characterized by a large number of circulating prolymphocytes. It can arise spontaneously or as a consequence of transformation of CHRONIC LYMPHOCYTIC LEUKEMIA.
] |
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Leukemia, Prolymphocytic, B-Cell
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D054403 |
[A neoplasm of prolymphocytes affecting the blood, bone marrow, and spleen. It is characterized by prolymphocytes exceeding 55% of the lymphoid cells in the blood and profound splenomegaly.
] |
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Leukemia, Prolymphocytic, T-Cell
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D015461 |
[A lymphoid leukemia characterized by a profound LYMPHOCYTOSIS with or without LYMPHADENOPATHY, hepatosplenomegaly, frequently rapid progression, and short survival. It was formerly called T-cell chronic lymphocytic leukemia.
] |
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Leukemia, Promyelocytic, Acute
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D015473 |
[An acute myeloid leukemia in which abnormal PROMYELOCYTES predominate. It is frequently associated with DISSEMINATED INTRAVASCULAR COAGULATION.
] |
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Leukemia, Radiation-Induced
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D007953 |
[Leukemia produced by exposure to IONIZING RADIATION or NON-IONIZING RADIATION.
] |
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Leukemia, T-Cell
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D015458 |
[A malignant disease of the T-LYMPHOCYTES in the bone marrow, thymus, and/or blood.
] |
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Leukemia-Lymphoma, Adult T-Cell
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D015459 |
[Aggressive T-Cell malignancy with adult onset, caused by HUMAN T-LYMPHOTROPIC VIRUS 1. It is endemic in Japan, the Caribbean basin, Southeastern United States, Hawaii, and parts of Central and South America and sub-Saharan Africa.
] |
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Leukemic Infiltration
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D017254 |
[A pathologic change in leukemia in which leukemic cells permeate various organs at any stage of the disease. All types of leukemia show various degrees of infiltration, depending upon the type of leukemia. The degree of infiltration may vary from site to site. The liver and spleen are common sites of infiltration, the greatest appearing in myelocytic leukemia, but infiltration is seen also in the granulocytic and lymphocytic types. The kidney is also a common site and of the gastrointestinal system, the stomach and ileum are commonly involved. In lymphocytic leukemia the skin is often infiltrated. The central nervous system too is a common site.
] |
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Leukemoid Reaction
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D007955 |
[A peripheral blood picture resembling that of leukemia or indistinguishable from it on the basis of morphologic appearance alone. (Dorland, 27th ed)
] |
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Leukoaraiosis
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D049292 |
[Non-specific white matter changes in the BRAIN, often seen after age 65. Changes include loss of AXONS; MYELIN pallor, GLIOSIS, loss of ependymal cells, and enlarged perivascular spaces. Leukoaraiosis is a risk factor for DEMENTIA and CEREBROVASCULAR DISORDERS.
] |
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Leukocidins
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D007956 |
[Pore forming proteins originally discovered for toxic activity to LEUKOCYTES. They are EXOTOXINS produced by some pathogenic STAPHYLOCOCCUS and STREPTOCOCCUS that destroy leukocytes by lysis of the cytoplasmic granules and are partially responsible for the pathogenicity of the organisms.
] |
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Leukocyte Adherence Inhibition Test
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D007957 |
[Test for cell-mediated antitumor immunity and related serum blocking factors based on the finding that leukocytes from cancer patients, but not from controls, when mixed in vitro with antigenic extracts of tumors of the same histological type, undergo a diminution in their normal adherence to glass surfaces. Sera from tumor-bearing patients block the LAI reaction of their own leukocytes or those of other patients with the same type of tumor.
] |
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Leukocyte Common Antigens
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D017493 |
[A splicing isoform of CD45 antigen that includes exon A.
, High-molecular weight glycoproteins uniquely expressed on the surface of LEUKOCYTES and their hemopoietic progenitors. They contain two FIBRONECTIN TYPE III DOMAINS and possess cytoplasmic protein tyrosine phosphatase activity, which plays a role in intracellular signaling from the CELL SURFACE RECEPTORS. Leukocyte common antigens occur as multiple isoforms that result from alternative mRNA splicing and differential usage of three exons.
, A splicing isoform of CD45 antigen that includes exon B.
, A splicing isoform of CD45 antigen that includes exon C.
, A low molecular weight isoform of CD45 antigen.
, A full-length splicing isoform of CD45 antigen.
] |
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Leukocyte Count
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D007958 |
[The number of WHITE BLOOD CELLS per unit volume in venous BLOOD. A differential leukocyte count measures the relative numbers of the different types of white cells.
] |
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Leukocyte Disorders
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D007960 |
[Disordered formation of various types of leukocytes or an abnormal accumulation or deficiency of these cells.
] |
