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Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
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D000071158 |
[A serine/threonine protein kinase with GTPase activity that contains 12 LEUCINE-rich repeats in its central region and 7 WD repeats C-terminal to its kinase and GTPase domains. It localizes to TRANSPORT VESICLES; the OUTER MITOCHONDRIAL MEMBRANE; and the GOLGI APPARATUS. It functions in PROTEIN TRANSPORT; regulates neuron morphology in the central nervous system, and also functions in the trafficking of SYNAPTIC VESICLES. Mutations in the LRRK2 gene have been identified in autosomal dominant cases of PARKINSON DISEASE (PARK8).
] |
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Leucine-tRNA Ligase
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D007935 |
[An enzyme that activates leucine with its specific transfer RNA. EC 6.1.1.4.
] |
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Leucogenenol
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D007932 |
[A heterocyclic enolic thymothyroid hormone synthesized by the THYMUS and/or THYROID.
] |
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Leucomycins
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D007933 |
[An antibiotic complex produced by Streptomyces kitasatoensis. The complex consists of a mixture of at least eight biologically active components, A1 and A3 to A9. Leucomycins have both antibacterial and antimycoplasmal activities.
] |
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Leuconostoc
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D007934 |
[A genus of gram-positive, facultatively anaerobic bacteria whose growth is dependent on the presence of a fermentable carbohydrate. It is nonpathogenic to plants and animals, including humans.
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Leuconostoc mesenteroides
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D000070007 |
[A species of Leuconostoc that occurs on fruits and vegetables and in their fermented products, as well as FERMENTED DAIRY PRODUCTS. It produces LACTIC ACID and BACTERIOCINS and is used as a PROBIOTIC; however, it has also caused infections in immunocompromised patients.
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Leuconostocaceae
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D056584 |
[A family of gram-positive bacteria in the order Lactobacillales. Lactic acid is the main product of their carbohydrate metabolism.
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Leucovorin
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D002955 |
[The active metabolite of FOLIC ACID. Leucovorin is used principally as an antidote to FOLIC ACID ANTAGONISTS.
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Leucyl Aminopeptidase
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D007931 |
[A zinc containing enzyme of the hydrolase class that catalyzes the removal of the N-terminal amino acid from most L-peptides, particularly those with N-terminal leucine residues but not those with N-terminal lysine or arginine residues. This occurs in tissue cell cytosol, with high activity in the duodenum, liver, and kidney. The activity of this enzyme is commonly assayed using a leucine arylamide chromogenic substrate such as leucyl beta-naphthylamide.
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Leukapheresis
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D007937 |
[The preparation of leukocyte concentrates with the return of red cells and leukocyte-poor plasma to the donor.
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Leukemia
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D007938 |
[A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
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Leukemia Inhibitory Factor
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D053605 |
[An INTERLEUKIN-6 related cytokine that exhibits pleiotrophic effects on many physiological systems that involve cell proliferation, differentiation, and survival. Leukemia inhibitory factor binds to and acts through the lif receptor.
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Leukemia Inhibitory Factor Receptor alpha Subunit
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D053680 |
[A receptor subunit that combines with CYTOKINE RECEPTOR GP130 to form the dual specificity receptor for LEUKEMIA INHIBITORY FACTOR and ONCOSTATIN M. The subunit is also a component of the CILIARY NEUROTROPHIC FACTOR RECEPTOR. Both membrane-bound and secreted isoforms of the receptor subunit exist due to ALTERNATIVE SPLICING of its mRNA. The secreted isoform is believed to act as an inhibitory receptor, while the membrane-bound form is a signaling receptor.
] |
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Leukemia L1210
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D007939 |
[An experimental LYMPHOCYTIC LEUKEMIA of mice.
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Leukemia L5178
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D007940 |
[An experimental lymphocytic leukemia of mice.
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Leukemia P388
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D007941 |
[An experimental lymphocytic leukemia originally induced in DBA/2 mice by painting with methylcholanthrene.
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Leukemia Virus, Bovine
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D001909 |
[The type species of DELTARETROVIRUS that causes a form of bovine lymphosarcoma (ENZOOTIC BOVINE LEUKOSIS) or persistent lymphocytosis.
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Leukemia Virus, Feline
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D005256 |
[A species of GAMMARETROVIRUS causing leukemia, lymphosarcoma, immune deficiency, or other degenerative diseases in cats. Several cellular oncogenes confer on FeLV the ability to induce sarcomas (see also SARCOMA VIRUSES, FELINE).
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Leukemia Virus, Gibbon Ape
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D017989 |
[A species of GAMMARETROVIRUS causing leukemia in the gibbon ape. Natural transmission is by contact.
] |
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Leukemia Virus, Murine
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D009052 |
[Species of GAMMARETROVIRUS, containing many well-defined strains, producing leukemia in mice. Disease is commonly induced by injecting filtrates of propagable tumors into newborn mice.
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