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Intercellular Adhesion Molecule-3
|
D000074001 |
[A membrane glycoprotein and cell adhesion molecule expressed by LEUKOCYTES that contains multiple Ig-like domains. It is a ligand for LFA-1 (integrin alphaLbeta2) and integrin alpha-D/beta-2. Its interaction with LFA-1 may play a role in the PHAGOCYTOSIS of NEUTROPHILS by MACROPHAGES following APOPTOSIS.
] |
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Intercellular Junctions
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D007365 |
[Direct contact of a cell with a neighboring cell. Most such junctions are too small to be resolved by light microscopy, but they can be visualized by conventional or freeze-fracture electron microscopy, both of which show that the interacting CELL MEMBRANE and often the underlying CYTOPLASM and the intervening EXTRACELLULAR SPACE are highly specialized in these regions. (From Alberts et al., Molecular Biology of the Cell, 2d ed, p792)
] |
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Intercellular Signaling Peptides and Proteins
|
D036341 |
[Regulatory proteins and peptides that are signaling molecules involved in the process of PARACRINE COMMUNICATION. They are generally considered factors that are expressed by one cell and are responded to by receptors on another nearby cell. They are distinguished from HORMONES in that their actions are local rather than distal.
] |
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Intercostal Muscles
|
D007366 |
[Respiratory muscles that arise from the lower border of one rib and insert into the upper border of the adjoining rib, and contract during inspiration or respiration. (From Stedman, 25th ed)
] |
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Intercostal Nerves
|
D007367 |
[The ventral rami of the thoracic nerves from segments T1 through T11. The intercostal nerves supply motor and sensory innervation to the thorax and abdomen. The skin and muscles supplied by a given pair are called, respectively, a dermatome and a myotome.
] |
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Interdepartmental Relations
|
D015274 |
[The interactions between representatives of institutional departments.
] |
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Interdisciplinary Communication
|
D033183 |
[Communication, in the sense of cross-fertilization of ideas, involving two or more academic disciplines (such as the disciplines that comprise the cross-disciplinary field of bioethics, including the health and biological sciences, the humanities, and the social sciences and law). Also includes differences in patterns of language usage in different academic or medical disciplines.
, An academic field that deals with processes of human communication.
] |
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Interdisciplinary Placement
|
D000073919 |
[Teaching strategy of shared learning based cross-discipline experiences and placements.
] |
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Interdisciplinary Research
|
D000075762 |
[Collaborative effort to address a scientific challenge that leverages the strengths and expertise of professionals trained in different fields. It encompasses both conceptual and methodological strategies aimed at understanding and enhancing the processes and outcomes of collaborative, team-based research. (from https://www.teamsciencetoolkit.cancer.gov/Public/WhatIsTS.aspx)
, Research combining mastery in distinct fields or disciplines that apply and exchange tools, concepts, ideas, data methods, or results around a common project.
] |
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Interdisciplinary Studies
|
D058025 |
[Programs of study which span the traditional boundaries of academic scholarship.
] |
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Interferometry
|
D007368 |
[Measurement of distances or movements by means of the phenomena caused by the interference of two rays of light (optical interferometry) or of sound (acoustic interferometry).
] |
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Interferon Inducers
|
D007369 |
[Agents that promote the production and release of interferons. They include mitogens, lipopolysaccharides, and the synthetic polymers Poly A-U and Poly I-C. Viruses, bacteria, and protozoa have been also known to induce interferons.
] |
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Interferon Regulatory Factor-1
|
D050856 |
[An interferon regulatory factor that binds upstream TRANSCRIPTIONAL REGULATORY ELEMENTS in the GENES for INTERFERON-ALPHA and INTERFERON-BETA. It functions as a transcriptional activator for the INTERFERON TYPE I genes.
] |
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Interferon Regulatory Factor-2
|
D050836 |
[An interferon regulatory factor that represses transcription of TYPE I INTERFERONS and activates transcription of HISTONE H4.
] |
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Interferon Regulatory Factor-3
|
D050838 |
[An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription.
] |
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Interferon Regulatory Factor-7
|
D050839 |
[An interferon regulatory factor that is induced by INTERFERONS as well as LMP-1 protein from EPSTEIN-BARR VIRUS. IRF-7 undergoes PHOSPHORYLATION prior to nuclear translocation and it activates GENETIC TRANSCRIPTION of multiple interferon GENES.
] |
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Interferon Regulatory Factors
|
D050835 |
[A family of transcription factors that share an N-terminal HELIX-TURN-HELIX MOTIF and bind INTERFERON-inducible promoters to control GENE expression. IRF proteins bind specific DNA sequences such as interferon-stimulated response elements, interferon regulatory elements, and the interferon consensus sequence.
] |
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Interferon Type I
|
D007370 |
[Interferon secreted by leukocytes, fibroblasts, or lymphoblasts in response to viruses or interferon inducers other than mitogens, antigens, or allo-antigens. They include alpha- and beta-interferons (INTERFERON-ALPHA and INTERFERON-BETA).
] |
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Interferon alpha-2
|
D000077190 |
[Alpha interferon encoded by the human IFNA2 gene. Recombinant forms are used in the treatment of CHRONIC HEPATITIS B; CHRONIC HEPATITIS C; KAPOSI SARCOMA; MELANOMA; and HAIRY CELL LEUKEMIA.
, A recombinant form of interferon alpha-2. This variant has ARGININE at position 23 and HISTIDINE at position 34
, A recombinant form of interferon alpha-2. This variant has LYSINE at position 23 and HISTIDINE at position 34.
] |
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Interferon beta-1a
|
D000068556 |
[An interferon beta-1 subtype that has a methionine at position 1, a cysteine at position 17, and is glycosylated at position 80. It functions as an ANTI-VIRAL AGENT and IMMUNOMODULATOR and is used to manage the symptoms of RELAPSING-REMITTING MULTIPLE SCLEROSIS.
] |