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Glia Maturation Factor
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D020904 |
[A factor identified in the brain that influences the growth and differentiation of NEURONS and NEUROGLIA. Glia maturation factor beta is the 17-kDa polypeptide product of the GMFB gene and is the principal component of GLIA MATURATION FACTOR.
] |
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Gliadin
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D005903 |
[Simple protein, one of the prolamines, derived from the gluten of wheat, rye, etc. May be separated into 4 discrete electrophoretic fractions. It is the toxic factor associated with CELIAC DISEASE.
] |
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Glial Cell Line-Derived Neurotrophic Factor
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D051100 |
[The founding member of the glial cell line-derived neurotrophic factor family. It was originally characterized as a NERVE GROWTH FACTOR promoting the survival of MIDBRAIN dopaminergic NEURONS, and it has been studied as a potential treatment for PARKINSON DISEASE.
] |
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Glial Cell Line-Derived Neurotrophic Factor Receptors
|
D051097 |
[A family of GLYCOSYLPHOSPHATIDYLINOSITOL-anchored cell surface receptors that are specific for GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTORS. They form a multi-component receptor complex with PROTO-ONCOGENE PROTEIN C-RET and regulate a variety of intracellular SIGNAL TRANSDUCTION PATHWAYS in conjunction with c-ret protein.
] |
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Glial Cell Line-Derived Neurotrophic Factors
|
D051098 |
[A family of closely related nerve growth factors that promote NEURON survival. They bind to GDNF RECEPTORS and stimulate SIGNAL TRANSDUCTION through PROTO-ONCOGENE PROTEIN C-RET.
] |
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Glial Fibrillary Acidic Protein
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D005904 |
[An intermediate filament protein found only in glial cells or cells of glial origin. MW 51,000.
] |
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Glicentin
|
D053771 |
[A 69-amino acid peptide derived from the N-terminal of PROGLUCAGON. It is mainly produced by the INTESTINAL L CELLS. Further processing of glicentin yield a 30-amino acid N-terminal peptide (glicentin-related polypeptide) and a 37-amino acid peptide OXYNTOMODULIN. Both glicentin and oxyntomodulin can reduce digestive secretions and delay gastric emptying.
] |
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Gliclazide
|
D005907 |
[An oral sulfonylurea hypoglycemic agent which stimulates insulin secretion.
] |
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Glioblastoma
|
D005909 |
[A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
] |
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Gliocladium
|
D020462 |
[A mitosporic fungal genus occurring in soil or decaying plant matter. It is structurally similar to Penicillium.
] |
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Glioma
|
D005910 |
[Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
] |
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Glioma, Subependymal
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D018315 |
[Rare, slow-growing, benign intraventricular tumors, often asymptomatic and discovered incidentally. The tumors are classified histologically as ependymomas and demonstrate a proliferation of subependymal fibrillary astrocytes among the ependymal tumor cells. (From Clin Neurol Neurosurg 1997 Feb;99(1):17-22)
] |
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Gliosarcoma
|
D018316 |
[Rare mixed tumors of the brain and rarely the spinal cord which contain malignant neuroectodermal (glial) and mesenchymal components, including spindle-shaped fibrosarcoma cells. These tumors are highly aggressive and present primarily in adults as rapidly expanding mass lesions. They may arise in tissue that has been previously irradiated. (From Br J Neurosurg 1995 Apr;9(2):171-8)
] |
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Gliosis
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D005911 |
[The production of a dense fibrous network of neuroglia; includes astrocytosis, which is a proliferation of astrocytes in the area of a degenerative lesion.
] |
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Gliotoxin
|
D005912 |
[A fungal toxin produced by various species of Trichoderma, Gladiocladium fimbriatum, Aspergillus fumigatus, and Penicillium. It is used as an immunosuppressive agent.
] |
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Glipizide
|
D005913 |
[An oral hypoglycemic agent which is rapidly absorbed and completely metabolized.
] |
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Global Burden of Disease
|
D000071219 |
[Measure of the burden of disease using the disability-adjusted-life-year (DALY). This time-based measure combines years of life lost due to premature mortality and years of life lost due to time lived in states of less than full health. The metric was developed to assess the burden of disease consistently across diseases, risk factors and regions.
] |
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Global Health
|
D014943 |
[The concept pertaining to the health status of inhabitants of the world.
, A multi- and interdisciplinary field concerned with improving health and achieving equity in health for all people. It transcends national boundaries, promotes cooperation and collaboration within and beyond health science fields, and combines population-based disease prevention with individually-based patient care.
] |
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Global Warming
|
D057232 |
[Increase in the temperature of the atmosphere near the Earth's surface and in the troposphere, which can contribute to changes in global climate patterns.
] |
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Globins
|
D005914 |
[A superfamily of proteins containing the globin fold which is composed of 6-8 alpha helices arranged in a characterstic HEME enclosing structure.
] |
