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Focal Adhesion Kinase 1
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D051417 |
[A non-receptor protein tyrosine kinase with PROTEIN PHOSPHATASE 1 regulatory activity that is localized to FOCAL ADHESIONS and is a central component of integrin-mediated SIGNAL TRANSDUCTION PATHWAYS. Focal adhesion kinase 1 interacts with PAXILLIN and undergoes PHOSPHORYLATION in response to adhesion of cell surface integrins to the EXTRACELLULAR MATRIX. Phosphorylated p125FAK protein binds to a variety of SH2 DOMAIN and SH3 DOMAIN containing proteins and helps regulate CELL ADHESION and CELL MIGRATION.
] |
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Focal Adhesion Kinase 2
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D051418 |
[A non-receptor protein-tyrosine kinase that is expressed primarily in the BRAIN; OSTEOBLASTS; and LYMPHOID CELLS. In the CENTRAL NERVOUS SYSTEM focal adhesion kinase 2 modulates ION CHANNEL function and MITOGEN-ACTIVATED PROTEIN KINASES activity.
] |
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Focal Adhesion Protein-Tyrosine Kinases
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D051416 |
[A family of non-receptor, PROLINE-rich protein-tyrosine kinases.
] |
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Focal Adhesions
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D022001 |
[An anchoring junction of the cell to a non-cellular substrate. It is composed of a specialized area of the plasma membrane where bundles of the ACTIN CYTOSKELETON terminate and attach to the transmembrane linkers, INTEGRINS, which in turn attach through their extracellular domains to EXTRACELLULAR MATRIX PROTEINS.
] |
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Focal Dermal Hypoplasia
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D005489 |
[A genetic skin disease characterized by hypoplasia of the dermis, herniations of fat, and hand anomalies. It is found exclusively in females and transmitted as an X-linked dominant trait.
] |
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Focal Epithelial Hyperplasia
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D017573 |
[Hyperplasia of the mucous membrane of the lips, tongue, and less commonly, the buccal mucosa, floor of the mouth, and palate, presenting soft, painless, round to oval sessile papules about 1 to 4 mm in diameter. The condition usually occurs in children and young adults and has familial predilection, lasting for several months, sometimes years, before running its course. A viral etiology is suspected, the isolated organism being usually the human papillomavirus. (Jablonski, Illustrated Dictionary of Dentistry; Belshe, Textbook of Human Virology, 2d ed, p954)
] |
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Focal Infection
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D005490 |
[An infection at a specific location that may spread to another region of the body.
] |
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Focal Infection, Dental
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D005491 |
[Secondary or systemic infections due to dissemination throughout the body of microorganisms whose primary focus of infection lies in the periodontal tissues.
] |
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Focal Nodular Hyperplasia
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D020518 |
[Solitary or multiple benign hepatic vascular tumors, usually occurring in women of 20-50 years of age. The nodule, poorly encapsulated, consists of a central stellate fibrous scar and normal liver elements such as HEPATOCYTES, small BILE DUCTS, and KUPFFER CELLS among the intervening fibrous septa. The pale colored central scar represents large blood vessels with hyperplastic fibromuscular layer and narrowing lumen.
] |
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Focus Groups
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D017144 |
[A method of data collection and a QUALITATIVE RESEARCH tool in which a small group of individuals are brought together and allowed to interact in a discussion of their opinions about topics, issues, or questions.
] |
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Focused Assessment with Sonography for Trauma
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D000077564 |
[Rapid bedside ultrasound examination performed by medical personnel (surgeons, emergency physicians, paramedics and others), as a screening test for blood around the heart (PERICARDIAL EFFUSION) or abdominal organs (HEMOPERITONEUM) after trauma.
] |
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Foeniculum
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D030001 |
[A plant genus of the family APIACEAE used in SPICES.
] |
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Folate Receptor 1
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D058975 |
[A subtype of GPI-anchored folate receptors that is expressed in tissues of epithelial origin. This protein is also identified as an ovarian-tumor-specific antigen.
] |
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Folate Receptor 2
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D058976 |
[A subtype of GPI-anchored folate receptors that is expressed in PLACENTA and hematopoietic cells.
] |
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Folate Receptors, GPI-Anchored
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D058973 |
[Cell surface receptors that bind to and transport FOLIC ACID, 5-methyltetrahydrofolate, and a variety of folic acid derivatives. The receptors are essential for normal NEURAL TUBE development and transport folic acid via receptor-mediated endocytosis.
] |
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Folic Acid
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D005492 |
[A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (POACEAE). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia.
] |
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Folic Acid Antagonists
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D005493 |
[Inhibitors of the enzyme, dihydrofolate reductase (TETRAHYDROFOLATE DEHYDROGENASE), which converts dihydrofolate (FH2) to tetrahydrofolate (FH4). They are frequently used in cancer chemotherapy. (From AMA, Drug Evaluations Annual, 1994, p2033)
] |
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Folic Acid Deficiency
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D005494 |
[A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)
] |
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Folic Acid Transporters
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D058972 |
[Proteins involved in the transport of FOLIC ACID and folate derivatives across the CELLULAR MEMBRANE.
] |
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Folklore
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D005495 |
[The common orally transmitted traditions, folktales, festivals, songs, superstitions, and stories of all peoples.
] |
