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Fibrinolytic Agents
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D005343 |
[Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN.
] |
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Fibrinopeptide A
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D005344 |
[Two small peptide chains removed from the N-terminal segment of the alpha chains of fibrinogen by the action of thrombin during the blood coagulation process. Each peptide chain contains 18 amino acid residues. In vivo, fibrinopeptide A is used as a marker to determine the rate of conversion of fibrinogen to fibrin by thrombin.
] |
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Fibrinopeptide B
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D005345 |
[Two small peptide chains removed from the N-terminal segment of the beta chains of fibrinogen by the action of thrombin. Each peptide chain contains 20 amino acid residues. The removal of fibrinopeptides B is not required for coagulation.
] |
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Fibroadenoma
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D018226 |
[An adenoma containing fibrous tissue. It should be differentiated from ADENOFIBROMA which is a tumor composed of connective tissue (fibroma) containing glandular (adeno-) structures. (From Dorland, 27th ed)
] |
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Fibrobacter
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D045848 |
[A genus of gram-negative, anaerobic bacteria in the family Fibrobacteraceae, isolated from the human GASTROINTESTINAL TRACT.
] |
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Fibrobacteres
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D061306 |
[A phylum of gram-negative bacteria closely related to the BACTEROIDETES. Species have been found in the gastrointestinal tracts of animals, especially termites, though indications are that species are more broadly distributed in other environments.
] |
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Fibroblast Growth Factor 1
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D016220 |
[A 17-kDa single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. It binds to HEPARIN, which potentiates its biological activity and protects it from proteolysis. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages, and also has chemotactic and mitogenic activities. It was originally named acidic fibroblast growth factor based upon its chemical properties and to distinguish it from basic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 2).
] |
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Fibroblast Growth Factor 10
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D051526 |
[A fibroblast growth factor that is a mitogen for KERATINOCYTES. It activates FIBROBLAST GROWTH FACTOR RECEPTOR 2B and is involved in LUNG and limb development.
] |
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Fibroblast Growth Factor 2
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D016222 |
[A single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FIBROBLAST GROWTH FACTOR 1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 1).
] |
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Fibroblast Growth Factor 3
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D051518 |
[A fibroblast growth factor that is expressed primarily during development.
] |
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Fibroblast Growth Factor 4
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D051519 |
[A HEPARIN binding fibroblast growth factor that may play a role in LIMB BUDS development.
] |
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Fibroblast Growth Factor 5
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D051521 |
[A fibroblast growth factor that may play a role in regulation of HAIR FOLLICLE phenotype. Spontaneous mutation of the gene for this protein results in a strain of MICE with abnormally long hair, referred to as angora mice.
] |
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Fibroblast Growth Factor 6
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D051522 |
[A fibroblast growth factor that was initially identified based on its sequence similarity to FIBROBLAST GROWTH FACTOR 4. It is found in MYOBLASTS and plays an important role in MUSCLE DEVELOPMENT.
] |
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Fibroblast Growth Factor 7
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D051523 |
[A fibroblast growth factor that is a specific mitogen for EPITHELIAL CELLS. It binds a complex of HEPARAN SULFATE and FIBROBLAST GROWTH FACTOR RECEPTOR 2B.
] |
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Fibroblast Growth Factor 8
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D051524 |
[A fibroblast growth factor that preferentially activates FIBROBLAST GROWTH FACTOR RECEPTOR 4. It was initially identified as an androgen-induced growth factor and plays a role in regulating growth of human BREAST NEOPLASMS and PROSTATIC NEOPLASMS.
] |
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Fibroblast Growth Factor 9
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D051525 |
[A fibroblast growth factor that was originally identified as a mitogen for GLIAL CELLS. It is expressed primarily in NEURONS.
] |
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Fibroblast Growth Factors
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D005346 |
[A family of small polypeptide growth factors that share several common features including a strong affinity for HEPARIN, and a central barrel-shaped core region of 140 amino acids that is highly homologous between family members. Although originally studied as proteins that stimulate the growth of fibroblasts this distinction is no longer a requirement for membership in the fibroblast growth factor family.
] |
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Fibroblasts
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D005347 |
[Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.
] |
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Fibrocartilage
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D051445 |
[A type of CARTILAGE whose matrix contains large bundles of COLLAGEN TYPE I. Fibrocartilage is typically found in the INTERVERTEBRAL DISK; PUBIC SYMPHYSIS; TIBIAL MENISCI; and articular disks in synovial JOINTS. (From Ross et. al., Histology, 3rd ed., p132,136)
] |
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Fibrocystic Breast Disease
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D005348 |
[A common and benign breast disease characterized by varying degree of fibrocystic changes in the breast tissue. There are three major patterns of morphological changes, including FIBROSIS, formation of CYSTS, and proliferation of glandular tissue (adenosis). The fibrocystic breast has a dense irregular, lumpy, bumpy consistency.
, A benign lesion of the BREAST, characterized by a proliferation of disorganized small glands lined by EPITHELIAL CELLS without apparent myoepithelial cells. These glands usually have enlarged lumens, and lie in adipose or fibrous tissue.
] |
