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Esthetics, Dental
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D004955 |
[Skills, techniques, standards, and principles used to improve the art and symmetry of the teeth and face to improve the appearance as well as the function of the teeth, mouth, and face. (From Boucher's Clinical Dental Terminology, 4th ed, p108)
] |
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Estivation
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D004956 |
[In certain living species, a period of dormancy during the summer months marked by decreased metabolism.
] |
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Estonia
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D004957 |
[A country in Eastern Europe, bordering the Baltic Sea and Gulf of Finland, between Latvia and Russia. The capital is Tallinn.
] |
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Estradiol
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D004958 |
[The 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids.
] |
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Estradiol Congeners
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D045166 |
[Steroidal compounds related to ESTRADIOL, the major mammalian female sex hormone. Estradiol congeners include important estradiol precursors in the biosynthetic pathways, metabolites, derivatives, and synthetic steroids with estrogenic activities.
, Compounds obtained by chemical synthesis which possess estrogenic activity, but differ in structure from naturally occurring estrogens.
] |
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Estradiol Dehydrogenases
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D004960 |
[Enzymes that catalyze the oxidation of estradiol at the 17-hydroxyl group in the presence of NAD+ or NADP+ to yield estrone and NADH or NADPH. The 17-hydroxyl group can be in the alpha- or beta-configuration. EC 1.1.1.62
] |
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Estramustine
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D004961 |
[A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
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Estranes
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D004962 |
[A group of compounds forming the nucleus of the estrogenic steroid family.
] |
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Estrenes
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D004963 |
[Unsaturated derivatives of the ESTRANES with methyl groups at carbon-13, with no carbon at carbon-10, and with no more than one carbon at carbon-17. They must contain one or more double bonds.
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Estriol
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D004964 |
[A hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During PREGNANCY, a large amount of estriol is produced by the PLACENTA. Isomers with inversion of the hydroxyl group or groups are called epiestriol.
] |
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Estrogen Antagonists
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D004965 |
[Compounds which inhibit or antagonize the action or biosynthesis of estrogenic compounds.
, Compounds which inhibit or antagonize the biosynthesis or action of estradiol.
] |
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Estrogen Receptor Antagonists
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D065171 |
[Compounds and drugs that bind to and block or inhibit the activation of ESTROGEN RECEPTORS.
] |
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Estrogen Receptor Modulators
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D020847 |
[Substances that possess antiestrogenic actions but can also produce estrogenic effects as well. They act as complete or partial agonist or as antagonist. They can be either steroidal or nonsteroidal in structure.
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Estrogen Receptor alpha
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D047628 |
[One of the ESTROGEN RECEPTORS that has marked affinity for ESTRADIOL. Its expression and function differs from, and in some ways opposes, ESTROGEN RECEPTOR BETA.
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Estrogen Receptor beta
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D047629 |
[One of the ESTROGEN RECEPTORS that has greater affinity for ISOFLAVONES than ESTROGEN RECEPTOR ALPHA does. There is great sequence homology with ER alpha in the DNA-binding domain but not in the ligand binding and hinge domains.
] |
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Estrogen Replacement Therapy
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D015914 |
[The use of hormonal agents with estrogen-like activity in postmenopausal or other estrogen-deficient women to alleviate effects of hormone deficiency, such as vasomotor symptoms, DYSPAREUNIA, and progressive development of OSTEOPOROSIS. This may also include the use of progestational agents in combination therapy.
] |
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Estrogenic Steroids, Alkylated
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D042782 |
[Estrogenic STEROIDS with aliphatic hydrocarbon chain substitution on C17 or other position. 17-alpha-ALKYLATION renders the molecule more stable, resistant to metabolic degradation, and improves oral efficacy. Examples of synthetic alkyl estrogens include ETHINYL ESTRADIOL and MESTRANOL. Substitutions at other sites generates antiestrogenic and cytotoxic properties.
] |
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Estrogens
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D004967 |
[Compounds that interact with ESTROGEN RECEPTORS in target tissues to bring about the effects similar to those of ESTRADIOL. Estrogens stimulate the female reproductive organs, and the development of secondary female SEX CHARACTERISTICS. Estrogenic chemicals include natural, synthetic, steroidal, or non-steroidal compounds.
] |
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Estrogens, Catechol
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D002393 |
[2- or 4-Hydroxyestrogens. Substances that are physiologically active in mammals, especially in the control of gonadotropin secretion. Physiological activity can be ascribed to either an estrogenic action or interaction with the catecholaminergic system.
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Estrogens, Conjugated (USP)
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D004966 |
[A pharmaceutical preparation containing a mixture of water-soluble, conjugated estrogens derived wholly or in part from URINE of pregnant mares or synthetically from ESTRONE and EQUILIN. It contains a sodium-salt mixture of estrone sulfate (52-62%) and equilin sulfate (22-30%) with a total of the two between 80-88%. Other concomitant conjugates include 17-alpha-dihydroequilin, 17-alpha-estradiol, and 17-beta-dihydroequilin. The potency of the preparation is expressed in terms of an equivalent quantity of sodium estrone sulfate.
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