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Dopamine Agonists
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D018491 |
[Drugs that bind to and activate dopamine receptors.
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Dopamine Antagonists
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D018492 |
[Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME.
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Dopamine D2 Receptor Antagonists
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D065127 |
[Compounds and drugs that bind to and inhibit or block the activation of DOPAMINE D2 RECEPTORS.
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Dopamine Plasma Membrane Transport Proteins
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D050483 |
[A dopamine plasma membrane transporter protein complex located on the membrane of dopaminergic neurons. The complex includes homo-oligomers of the DAT Dopamine Transporter.
, Sodium chloride-dependent neurotransmitter symporters located primarily on the PLASMA MEMBRANE of dopaminergic neurons. They remove DOPAMINE from the EXTRACELLULAR SPACE by high affinity reuptake into PRESYNAPTIC TERMINALS and are the target of DOPAMINE UPTAKE INHIBITORS.
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Dopamine Uptake Inhibitors
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D018765 |
[Drugs that block the transport of DOPAMINE into axon terminals or into storage vesicles within terminals. Most of the ADRENERGIC UPTAKE INHIBITORS also inhibit dopamine uptake.
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Dopamine and cAMP-Regulated Phosphoprotein 32
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D051937 |
[A phosphoprotein that was initially identified as a major target of DOPAMINE activated ADENYLYL CYCLASE in the CORPUS STRIATUM. It regulates the activities of PROTEIN PHOSPHATASE-1 and PROTEIN KINASE A, and it is a key mediator of the biochemical, electrophysiological, transcriptional, and behavioral effects of DOPAMINE.
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Dopamine beta-Hydroxylase
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D004299 |
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Dopaminergic Neurons
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D059290 |
[Neurons whose primary neurotransmitter is DOPAMINE.
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Doping in Sports
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D004300 |
[Illegitimate use of substances for a desired effect in competitive sports. It includes humans and animals.
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Doppler Effect
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D004301 |
[Changes in the observed frequency of waves (as sound, light, or radio waves) due to the relative motion of source and observer. The effect was named for the 19th century Austrian physicist Johann Christian Doppler.
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Doripenem
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D000077726 |
[A carbapenem derivative antibacterial agent that is more stable to renal dehydropeptidase I than IMIPENEM, but does not need to be given with an enzyme inhibitor such as CILASTATIN. It is used in the treatment of infections such as HOSPITAL-ACQUIRED PNEUMONIA, and complicated intra-abdominal or urinary-tract infections, including PYELONEPHRITIS.
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Dorsal Raphe Nucleus
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D065847 |
[The dorsal region of the raphe nucleus which is a source of the SEROTONERGIC NEURONS innervating the TELENCEPHALON; DIENCEPHALON; MESENCEPHALON; and RHOMBENCEPHALON.
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Dorsomedial Hypothalamic Nucleus
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D004302 |
[An aggregation of cells in the middle hypothalamus dorsal to the ventromedial nucleus and bordering the THIRD VENTRICLE.
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Dosage Compensation, Genetic
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D004303 |
[Genetic mechanisms that allow GENES to be expressed at a similar level irrespective of their GENE DOSAGE. This term is usually used in discussing genes that lie on the SEX CHROMOSOMES. Because the sex chromosomes are only partially homologous, there is a different copy number, i.e., dosage, of these genes in males vs. females. In DROSOPHILA, dosage compensation is accomplished by hypertranscription of genes located on the X CHROMOSOME. In mammals, dosage compensation of X chromosome genes is accomplished by random X CHROMOSOME INACTIVATION of one of the two X chromosomes in the female.
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Dosage Forms
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D004304 |
[Completed forms of the pharmaceutical preparation in which prescribed doses of medication are included. They are designed to resist action by gastric fluids, prevent vomiting and nausea, reduce or alleviate the undesirable taste and smells associated with oral administration, achieve a high concentration of drug at target site, or produce a delayed or long-acting drug effect.
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Dose Fractionation, Radiation
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D019583 |
[Administration of the total dose of radiation (RADIATION DOSAGE) in parts, at timed intervals.
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Dose-Response Relationship, Drug
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D004305 |
[The relationship between the dose of an administered drug and the response of the organism to the drug.
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Dose-Response Relationship, Immunologic
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D004306 |
[A specific immune response elicited by a specific dose of an immunologically active substance or cell in an organism, tissue, or cell.
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Dose-Response Relationship, Radiation
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D004307 |
[The relationship between the dose of administered radiation and the response of the organism or tissue to the radiation.
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Dothiepin
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D004308 |
[A tricyclic antidepressant with some tranquilizing action.
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