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Dihydrolipoyllysine-Residue Acetyltransferase
|
D051047 |
[An enzyme that catalyzes the acetyltransferase reaction using ACETYL CoA as an acetyl donor and dihydrolipoamide as acceptor to produce COENZYME A (CoA) and S-acetyldihydrolipoamide. It forms the (E2) subunit of the PYRUVATE DEHYDROGENASE COMPLEX.
] |
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Dihydromorphine
|
D004090 |
[A semisynthetic analgesic used in the study of narcotic receptors.
] |
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Dihydroorotase
|
D004080 |
[An enzyme that, in the course of pyrimidine biosynthesis, catalyzes ring closure by removal of water from N-carbamoylaspartate to yield dihydro-orotic acid. EC 3.5.2.3.
] |
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Dihydroorotate Oxidase
|
D004081 |
[An enzyme that in the course of pyrimidine biosynthesis, catalyzes the oxidation of dihydro-orotic acid to orotic acid utilizing oxygen as the electron acceptor. This enzyme is a flavoprotein which contains both FLAVIN-ADENINE DINUCLEOTIDE and FLAVIN MONONUCLEOTIDE as well as iron-sulfur centers. EC 1.3.3.1.
] |
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Dihydropteridine Reductase
|
D004093 |
[An enzyme that catalyzes the reduction of 6,7-dihydropteridine to 5,6,7,8-tetrahydropteridine in the presence of NADP+. Defects in the enzyme are a cause of PHENYLKETONURIA II. Formerly listed as EC 1.6.99.7.
] |
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Dihydropteroate Synthase
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D004094 |
[An enzyme that catalyzes the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate. EC 2.5.1.15.
] |
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Dihydropyridines
|
D004095 |
[Pyridine moieties which are partially saturated by the addition of two hydrogen atoms in any position.
] |
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Dihydropyrimidine Dehydrogenase Deficiency
|
D054067 |
[An autosomal recessive disorder affecting DIHYDROPYRIMIDINE DEHYDROGENASE and causing familial pyrimidinemia. It is characterized by thymine-uraciluria in homozygous deficient patients. Even a partial deficiency in the enzyme leaves individuals at risk for developing severe 5-FLUOROURACIL-associated toxicity.
] |
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Dihydrostilbenoids
|
D000081014 |
[Organic compounds characterized by the functional group 1,2-dihydrostilbene.
] |
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Dihydrostreptomycin Sulfate
|
D004096 |
[A semi-synthetic aminoglycoside antibiotic that is used in the treatment of TUBERCULOSIS.
] |
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Dihydrotachysterol
|
D004097 |
[A VITAMIN D that can be regarded as a reduction product of vitamin D2.
] |
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Dihydrotestosterone
|
D013196 |
[A potent androgenic metabolite of TESTOSTERONE. It is produced by the action of the enzyme 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE.
] |
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Dihydrouracil Dehydrogenase (NAD+)
|
D050744 |
[An enzyme that catalyzes the oxidation of 5,6-dihydrouracil to URACIL using NAD as a cofactor. This enzyme also plays a role in the catabolism of the antimetabolite 5-FLUOROURACIL.
] |
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Dihydrouracil Dehydrogenase (NADP)
|
D042943 |
[An oxidoreductase involved in pyrimidine base degradation. It catalyzes the catabolism of THYMINE; URACIL and the chemotherapeutic drug, 5-FLUOROURACIL.
] |
|
Dihydroxyacetone
|
D004098 |
[A ketotriose compound. Its addition to blood preservation solutions results in better maintenance of 2,3-diphosphoglycerate levels during storage. It is readily phosphorylated to dihydroxyacetone phosphate by triokinase in erythrocytes. In combination with naphthoquinones it acts as a sunscreening agent.
] |
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Dihydroxyacetone Phosphate
|
D004099 |
[An important intermediate in lipid biosynthesis and in glycolysis.
] |
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Dihydroxycholecalciferols
|
D004100 |
[Cholecalciferols substituted with two hydroxy groups in any position.
] |
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Dihydroxydihydrobenzopyrenes
|
D004101 |
[Benzopyrenes saturated in any two adjacent positions and substituted with two hydroxyl groups in any position. The majority of these compounds have carcinogenic or mutagenic activity.
] |
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Dihydroxyphenylalanine
|
D004295 |
[A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
] |
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Dihydroxytryptamines
|
D004102 |
[Tryptamine substituted with two hydroxyl groups in any position. Some are cytotoxic serotonin analogs that are preferentially taken up by serotonergic neurons and then destroy those neurons.
] |