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Desensitization, Immunologic
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D003888 |
[Immunosuppression by the administration of increasing doses of antigen. Though the exact mechanism is not clear, the therapy results in an increase in serum levels of allergen-specific IMMUNOGLOBULIN G, suppression of specific IgE, and an increase in suppressor T-cell activity.
] |
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Desensitization, Psychologic
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D003887 |
[A behavior therapy technique in which deep muscle relaxation is used to inhibit the effects of graded anxiety-evoking stimuli.
] |
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Desert Climate
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D003889 |
[A type of climate characterized by insufficient moisture to support appreciable plant life. It is a climate of extreme aridity, usually of extreme heat, and of negligible rainfall. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
] |
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Desflurane
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D000077335 |
[A fluorinated ether that is used as a volatile anesthetic for maintenance of general anesthesia.
] |
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Desiccation
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D003890 |
[Removal of moisture from a substance (chemical, food, tissue, etc.).
] |
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Designer Drugs
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D015198 |
[Drugs designed and synthesized, often for illegal street use, by modification of existing drug structures (e.g., amphetamines). Of special interest are MPTP (a reverse ester of meperidine), MDA (3,4-methylenedioxyamphetamine), and MDMA (3,4-methylenedioxymethamphetamine). Many drugs act on the aminergic system, the physiologically active biogenic amines.
] |
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Desipramine
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D003891 |
[A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
] |
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Deslanoside
|
D003892 |
[Deacetyllanatoside C. A cardiotonic glycoside from the leaves of Digitalis lanata.
] |
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Desmidiales
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D058114 |
[An order of mostly unicellular, microscopic, freshwater algae that have highly symmetrical and varied shapes.
] |
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Desmin
|
D003893 |
[An intermediate filament protein found predominantly in smooth, skeletal, and cardiac muscle cells. Localized at the Z line. MW 50,000 to 55,000 is species dependent.
] |
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Desmocollins
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D051187 |
[A group of desmosomal cadherins with cytoplasmic tails that are divergent from those of classical CADHERINS. Their intracytoplasmic domains bind PLAKOGLOBIN; PLAKOPHILINS; and DESMOPLAKINS.
] |
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Desmoglein 1
|
D051183 |
[A desmosomal cadherin that is an autoantigen in the acquired skin disorder PEMPHIGUS FOLIACEUS.
] |
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Desmoglein 2
|
D051301 |
[A CALCIUM-dependent adhesion molecule of DESMOSOMES that also plays a role in embryonic STEM CELL proliferation.
] |
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Desmoglein 3
|
D051184 |
[A desmosomal cadherin that is an autoantigen in the acquired skin disorder PEMPHIGUS VULGARIS.
] |
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Desmogleins
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D051182 |
[A group of desmosomal cadherins with cytoplasmic tails that resemble those of classical CADHERINS.
] |
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Desmoplakins
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D051180 |
[Desmoplakins are cytoskeletal linker proteins that anchor INTERMEDIATE FILAMENTS to the PLASMA MEMBRANE at DESMOSOMES.
] |
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Desmoplastic Small Round Cell Tumor
|
D058405 |
[A rare, aggressive soft tissue sarcoma that primarily affects adolescents and young adults. It is most commonly found in the abdomen.
] |
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Desmosine
|
D003895 |
[A rare amino acid found in elastin, formed by condensation of four molecules of lysine into a pyridinium ring.
] |
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Desmosomal Cadherins
|
D051181 |
[A single-pass transmembrane glycoproteins that mediate CALCIUM-dependent CELL ADHESION and are core components of DESMOSOMES.
] |
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Desmosomes
|
D003896 |
[A type of junction that attaches one cell to its neighbor. One of a number of differentiated regions which occur, for example, where the cytoplasmic membranes of adjacent epithelial cells are closely apposed. It consists of a circular region of each membrane together with associated intracellular microfilaments and an intercellular material which may include, for example, mucopolysaccharides. (From Glick, Glossary of Biochemistry and Molecular Biology, 1990; Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
] |