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Cysteine Loop Ligand-Gated Ion Channel Receptors
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D058466 |
[A subfamily of ligand-gated ion channel receptors that share a characteristic loop which is formed by a disulfide bond between two CYSTEINE residues. These receptors typically contain five subunits with the cysteine-loop occurring near an N-terminal extracellular domain.
] |
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Cysteine Proteases
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D057056 |
[A subclass of peptide hydrolases that depend on a CYSTEINE residue for their activity.
] |
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Cysteine Proteinase Inhibitors
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D015853 |
[Exogenous and endogenous compounds which inhibit CYSTEINE ENDOPEPTIDASES.
] |
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Cysteine Synthase
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D003547 |
[An enzyme that catalyzes the biosynthesis of cysteine in microorganisms and plants from O-acetyl-L-serine and hydrogen sulfide. This enzyme was formerly listed as EC 4.2.99.8.
] |
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Cysteine-Rich Protein 61
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D055515 |
[A CCN protein family member that regulates a variety of extracellular functions including CELL ADHESION; CELL MIGRATION; and EXTRACELLULAR MATRIX synthesis. It may play an important role in the development of branched CAPILLARIES during EMBRYOGENESIS.
] |
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Cysteinyldopa
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D003548 |
[Found in large amounts in the plasma and urine of patients with malignant melanoma. It is therefore used in the diagnosis of melanoma and for the detection of postoperative metastases. Cysteinyldopa is believed to be formed by the rapid enzymatic hydrolysis of 5-S-glutathionedopa found in melanin-producing cells.
] |
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Cystic Adenomatoid Malformation of Lung, Congenital
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D015615 |
[This type is microcystic, characterized by multiple cysts of 0.5 to 2.5 cm.
, This type is characterized by a bulky solid mass with cysts of <0.5 cm.
, This type is macrocystic, characterized by a single or multiple cysts of >2.5 cm.
, An abnormality in lung development that is characterized by a multicystic mass resulting from an adenomatous overgrowth of the terminal BRONCHIOLES with a consequent reduction of PULMONARY ALVEOLI. This anomaly is classified into three types by the cyst size.
] |
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Cystic Duct
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D003549 |
[The duct that is connected to the GALLBLADDER and allows the emptying of bile into the COMMON BILE DUCT.
] |
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Cystic Fibrosis
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D003550 |
[An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
] |
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Cystic Fibrosis Transmembrane Conductance Regulator
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D019005 |
[A chloride channel that regulates secretion in many exocrine tissues. Abnormalities in the CFTR gene have been shown to cause cystic fibrosis. (Hum Genet 1994;93(4):364-8)
] |
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Cysticercosis
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D003551 |
[Infection with CYSTICERCUS, the larval form of the various tapeworms of the genus Taenia (usually T. solium in man). In humans they penetrate the intestinal wall and invade subcutaneous tissue, brain, eye, muscle, heart, liver, lung, and peritoneum. Brain involvement results in NEUROCYSTICERCOSIS.
] |
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Cysticercus
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D003552 |
[The larval form of various tapeworms of the genus Taenia.
] |
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Cystine
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D003553 |
[A covalently linked dimeric nonessential amino acid formed by the oxidation of CYSTEINE. Two molecules of cysteine are joined together by a disulfide bridge to form cystine.
] |
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Cystine Depleting Agents
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D065104 |
[Compounds and drugs that react with CYSTINE and convert it into a compound that can be more easily metabolized or intracellularly transported. Drugs in this class have been used to treat CYSTINOSIS.
] |
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Cystine Knot Motifs
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D047168 |
[Amino acid sequence in which two disulfide bonds (DISULFIDES) and their connecting backbone form a ring that is penetrated by a third disulfide bond. Members include CYCLOTIDES and agouti-related protein.
] |
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Cystine-Knot Miniproteins
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D057771 |
[A structurally-related family of small proteins that form a stable tertiary fold pattern which is supported by a series of disulfide bonds. The arrangement of disulfide bonds between the CYSTEINE moieties results in a knotted structure which is unique to this family of proteins.
] |
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Cystinosis
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D003554 |
[A metabolic disease characterized by the defective transport of CYSTINE across the lysosomal membrane due to mutation of a membrane protein cystinosin. This results in cystine accumulation and crystallization in the cells causing widespread tissue damage. In the KIDNEY, nephropathic cystinosis is a common cause of RENAL FANCONI SYNDROME.
] |
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Cystinuria
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D003555 |
[An inherited disorder due to defective reabsorption of CYSTINE and other BASIC AMINO ACIDS by the PROXIMAL RENAL TUBULES. This form of aminoaciduria is characterized by the abnormally high urinary levels of cystine; LYSINE; ARGININE; and ORNITHINE. Mutations involve the amino acid transport protein gene SLC3A1.
] |
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Cystinyl Aminopeptidase
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D010122 |
[A zinc-containing sialoglycoprotein that is used to study aminopeptidase activity in the pathogenesis of hypertension. EC 3.4.11.3.
] |
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Cystitis
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D003556 |
[Inflammation of the URINARY BLADDER, either from bacterial or non-bacterial causes. Cystitis is usually associated with painful urination (dysuria), increased frequency, urgency, and suprapubic pain.
] |
