All individuals in MeSH

Label Id Description
Cyclin-Dependent Kinase Inhibitor p15 D050762 [An INK4 cyclin-dependent kinase inhibitor containing four ANKYRIN-LIKE REPEATS. INK4B is often inactivated by deletions, mutations, or hypermethylation in HEMATOLOGIC NEOPLASMS. ]
Cyclin-Dependent Kinase Inhibitor p16 D019941 [A product of the p16 tumor suppressor gene (GENES, P16). It is also called INK4 or INK4A because it is the prototype member of the INK4 CYCLIN-DEPENDENT KINASE INHIBITORS. This protein is produced from the alpha mRNA transcript of the p16 gene. The other gene product, produced from the alternatively spliced beta transcript, is TUMOR SUPPRESSOR PROTEIN P14ARF. Both p16 gene products have tumor suppressor functions. ]
Cyclin-Dependent Kinase Inhibitor p18 D050763 [An INK4 cyclin-dependent kinase inhibitor containing five ANKYRIN-LIKE REPEATS. Aberrant expression of this protein has been associated with deregulated EPITHELIAL CELL growth, organ enlargement, and a variety of NEOPLASMS. ]
Cyclin-Dependent Kinase Inhibitor p19 D050764 [An INK4 cyclin-dependent kinase inhibitor containing five ANKYRIN REPEATS. Aberrant expression of this protein has been associated with TESTICULAR CANCER. ]
Cyclin-Dependent Kinase Inhibitor p21 D050759 [A cyclin-dependent kinase inhibitor that mediates TUMOR SUPPRESSOR PROTEIN P53-dependent CELL CYCLE arrest. p21 interacts with a range of CYCLIN-DEPENDENT KINASES and associates with PROLIFERATING CELL NUCLEAR ANTIGEN and CASPASE 3. ]
Cyclin-Dependent Kinase Inhibitor p27 D050760 [A cyclin-dependent kinase inhibitor that coordinates the activation of CYCLIN and CYCLIN-DEPENDENT KINASES during the CELL CYCLE. It interacts with active CYCLIN D complexed to CYCLIN-DEPENDENT KINASE 4 in proliferating cells, while in arrested cells it binds and inhibits CYCLIN E complexed to CYCLIN-DEPENDENT KINASE 2. ]
Cyclin-Dependent Kinase Inhibitor p57 D050761 [A potent inhibitor of CYCLIN-DEPENDENT KINASES in G1 PHASE and S PHASE. In humans, aberrant expression of p57 is associated with various NEOPLASMS as well as with BECKWITH-WIEDEMANN SYNDROME. ]
Cyclin-Dependent Kinases D018844 [Protein kinases that control cell cycle progression in all eukaryotes and require physical association with CYCLINS to achieve full enzymatic activity. Cyclin-dependent kinases are regulated by phosphorylation and dephosphorylation events. ]
Cyclins D016213 [A large family of regulatory proteins that function as accessory subunits to a variety of CYCLIN-DEPENDENT KINASES. They generally function as ENZYME ACTIVATORS that drive the CELL CYCLE through transitions between phases. A subset of cyclins may also function as transcriptional regulators. ]
Cyclitols D054812 [Cycloalkanes containing three or more hydroxyl groups on the ring atoms. Some polyhydroxypiperidines (PIPERIDINES) are called iminocyclitols or aza-sugars. ]
Cyclization D003500 [Changing an open-chain hydrocarbon to a closed ring. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed) ]
Cyclizine D003501 [A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in motion sickness. (From Martindale, The Extra Pharmacopoeia, 30th ed, p935) ]
Cycloaddition Reaction D061565 [Synthetic organic reactions that use reactions between unsaturated molecules to form cyclical products. ]
Cyclobutanes D003503 [Four carbon cycloparaffin cyclobutane (the structural formula (CH2)4) and its derivatives. ]
Cyclodecanes D043822 [Compounds with a 10-carbon ring. ]
Cyclodextrins D003505 [A homologous group of cyclic GLUCANS consisting of alpha-1,4 bound glucose units obtained by the action of cyclodextrin glucanotransferase on starch or similar substrates. The enzyme is produced by certain species of Bacillus. Cyclodextrins form inclusion complexes with a wide variety of substances. ]
Cyclodialysis Clefts D000080322 [Finding of a separation of the CILIARY BODY in the SCLERAL SPUR region, creating aqueous outflow from the ANTERIOR CHAMBER into suprachoroidal space between the CHOROID and the SCLERA. Persistent cyclodialysis clefts may be associated with OCULAR HYPOTENSION and OPTIC DISC EDEMA. ]
Cyclofenil D003506 [A gonadal stimulant and inducer of ovulation. It is used in the treatment of infertility and amenorrhea, but is thought to be less effective than CLOMIPHENE. ]
Cycloheptanes D003508 [Seven-carbon cycloparaffin cycloheptane (the structural formula (CH2)7) and its derivatives. ]
Cyclohexane Monoterpenes D000081005 [Monoterpenes that include a cyclohexane ring in their structure. ]