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Cockayne Syndrome
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D003057 |
[Type C is a rare form. Its genetic defect is not clear; appears to be a heterogeneous group. OMIM suggests that Type C should not be used anymore.
, A syndrome characterized by multiple system abnormalities including DWARFISM; PHOTOSENSITIVITY DISORDERS; PREMATURE AGING; and HEARING LOSS. It is caused by mutations of a number of autosomal recessive genes encoding proteins that involve transcriptional-coupled DNA REPAIR processes. Cockayne syndrome is classified by the severity and age of onset. Type I (classical; CSA) is early childhood onset in the second year of life; type II (congenital; CSB) is early onset at birth with severe symptoms; type III (xeroderma pigmentosum; XP) is late childhood onset with mild symptoms.
, Caused by mutations of gene ERCC6.
, Caused by mutations of gene CKN1.
] |
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Cockroaches
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D003058 |
[Insects of the order Dictyoptera comprising several families including Blaberidae, BLATTELLIDAE, Blattidae (containing the American cockroach PERIPLANETA americana), Cryptocercidae, and Polyphagidae.
] |
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Coconut Oil
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D000074263 |
[Oil derived from fruits of the coconut plant, COCOS NUCIFERA.
] |
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Cocos
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D003059 |
[A plant genus of the family ARECACEAE. It is a tropical palm tree that yields a large, edible hard-shelled fruit from which oil and fiber are also obtained.
] |
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Coculture Techniques
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D018920 |
[A technique of culturing mixed cell types in vitro to allow their synergistic or antagonistic interactions, such as on CELL DIFFERENTIATION or APOPTOSIS. Coculture can be of different types of cells, tissues, or organs from normal or disease states.
] |
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Cod Liver Oil
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D003060 |
[Oil obtained from fresh livers of the cod family, Gadidae. It is a source of VITAMIN A and VITAMIN D.
] |
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Codeine
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D003061 |
[An opioid analgesic related to MORPHINE but with less potent analgesic properties and mild sedative effects. It also acts centrally to suppress cough.
] |
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Codependency, Psychological
|
D017004 |
[A relational pattern in which a person attempts to derive a sense of purpose through relationships with others.
] |
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Codes of Ethics
|
D032781 |
[Systematic statements of principles or rules of appropriate professional conduct, usually established by professional societies.
] |
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Codon
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D003062 |
[Any of the codons of an organism's GENETIC CODE that specify an amino acid.
, A set of three nucleotides in a protein coding sequence that specifies individual amino acids or a termination signal (CODON, TERMINATOR). Most codons are universal, but some organisms do not produce the transfer RNAs (RNA, TRANSFER) complementary to all codons. These codons are referred to as unassigned codons (CODONS, NONSENSE).
] |
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Codon Usage
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D000081183 |
[The frequency of occurrence, in a specific organism's DNA sequence, of one of several potential synonymous codons that code for a particular amino acid. Frequently, there is a nonrandom pattern (bias) in the usage of a particular codon or codons over other synonymous codons.
] |
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Codon, Initiator
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D018387 |
[A codon that directs initiation of protein translation (TRANSLATION, GENETIC) by stimulating the binding of initiator tRNA (RNA, TRANSFER, MET). In prokaryotes, the codons AUG or GUG can act as initiators while in eukaryotes, AUG is the only initiator codon.
] |
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Codon, Nonsense
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D018389 |
[A codon that is not assigned to an amino acid and is not a stop codon (CODON, TERMINATOR). Although they may lead to premature termination of translation, unassigned codons do not bind translation release factors (PEPTIDE TERMINATION FACTORS), as do stop codons.
, An amino acid-specifying codon that has been converted to a stop codon (CODON, TERMINATOR) by mutation. Its occurance is abnormal causing premature termination of protein translation and results in production of truncated and non-functional proteins. A nonsense mutation is one that converts an amino acid-specific codon to a stop codon.
, A mutation that converts a sense codon (CODON) into a stop codon (CODON, TERMINATOR) or an unassigned codon and leads to the formation of truncated proteins.
] |
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Codon, Terminator
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D018388 |
[Any codon that signals the termination of genetic translation (TRANSLATION, GENETIC). PEPTIDE TERMINATION FACTORS bind to the stop codon and trigger the hydrolysis of the aminoacyl bond connecting the completed polypeptide to the tRNA. Terminator codons do not specify amino acids.
] |
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Codonopsis
|
D029745 |
[A plant genus of the family CAMPANULACEAE. The common name of bellflower may sometimes be confused with other plants in the family that have similar appearance.
] |
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Coelomomyces
|
D055135 |
[A genus of fungi in the phylum BLASTOCLADIOMYCOTA. They exhibit complex life cycles and are parasitic on the larvae of MOSQUITOES.
] |
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Coenzyme A
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D003065 |
|
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Coenzyme A Ligases
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D003066 |
[Enzymes that catalyze the formation of acyl-CoA derivatives. EC 6.2.1.
] |
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Coenzyme A-Transferases
|
D015256 |
[Enzymes which transfer coenzyme A moieties from acyl- or acetyl-CoA to various carboxylic acceptors forming a thiol ester. Enzymes in this group are instrumental in ketone body metabolism and utilization of acetoacetate in mitochondria. EC 2.8.3.
] |
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Coenzymes
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D003067 |
[Small molecules that are required for the catalytic function of ENZYMES. Many VITAMINS are coenzymes.
] |
