|
Classical Article
|
D016419 |
[Works consisting of a current presentation of a previously printed seminal article marking a milestone in the history of medicine or science. It is usually accompanied by introductory remarks heralding its reprinting, often on the anniversary of its original publication or on an anniversary of the author's birth or death. It is usually reprinted in full, with complete bibliographical reference to the original appearance.
] |
|
Classical Lissencephalies and Subcortical Band Heterotopias
|
D054221 |
[Disorders comprising a spectrum of brain malformations representing the paradigm of a diffuse neuronal migration disorder. They result in cognitive impairment; SEIZURES; and HYPOTONIA or spasticity. Mutations of two genes, LIS1, the gene for the non-catalytic subunit of PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB; and DCX or XLIS, the gene for doublecortin, have been identified as the most common causes of disorders in this spectrum. Additional variants of classical (Type I) lissencephaly have been linked to RELN, the gene for reelin, and ARX, the gene for aristaless related homeobox protein. (From Leventer, R.J., et al, Mol Med Today. 2000 Jul;6(7):277-84 and Barkovich, A.J., et al, Neurology. 2005 Dec 27;65(12):1873-87.)
] |
|
Classical Swine Fever
|
D006691 |
[An acute, highly contagious disease affecting swine of all ages and caused by the CLASSICAL SWINE FEVER VIRUS. It has a sudden onset with high morbidity and mortality.
] |
|
Classical Swine Fever Virus
|
D006692 |
[A species of the PESTIVIRUS genus causing exceedingly contagious and fatal hemorrhagic disease of swine.
] |
|
Classification
|
D002965 |
[The systematic arrangement of entities in any field into categories classes based on common characteristics such as properties, morphology, subject matter, etc.
] |
|
Clathrin
|
D002966 |
[The main structural coat protein of COATED VESICLES which play a key role in the intracellular transport between membranous organelles. Each molecule of clathrin consists of three light chains (CLATHRIN LIGHT CHAINS) and three heavy chains (CLATHRIN HEAVY CHAINS) that form a structure called a triskelion. Clathrin also interacts with cytoskeletal proteins.
] |
|
Clathrin Heavy Chains
|
D033922 |
[The heavy chain subunits of clathrin.
] |
|
Clathrin Light Chains
|
D033941 |
[The light chain subunits of clathrin.
] |
|
Clathrin-Coated Vesicles
|
D022163 |
[Vesicles formed when cell-membrane coated pits (COATED PITS, CELL-MEMBRANE) invaginate and pinch off. The outer surface of these vesicles is covered with a lattice-like network of the protein CLATHRIN. Shortly after formation, however, the clathrin coat is removed and the vesicles are referred to as ENDOSOMES.
] |
|
Claudin-1
|
D062445 |
[An integral membrane protein that is localized to TIGHT JUNCTIONS, where it plays a role in controlling the paracellular permeability of polarized cells. Mutations in the gene for claudin-1 are associated with Neonatal Ichthyosis-Sclerosing Cholangitis (NISCH) Syndrome.
] |
|
Claudin-2
|
D062446 |
[A claudin subtype that is associated with the formation of cation-selective channels and increased epithelial permeability. It is localized to the TIGHT JUNCTIONS of the PROXIMAL KIDNEY TUBULE and INTESTINAL EPITHELIUM.
] |
|
Claudin-3
|
D062465 |
[A ubiquitously-expressed claudin subtype that acts as a general barrier-forming protein in TIGHT JUNCTIONS. Elevated expression of claudin-3 is found in a variety of tumor cell types, suggesting its role as a therapeutic target for specific ANTINEOPLASTIC AGENTS.
] |
|
Claudin-4
|
D062506 |
[A claudin subtype that takes part in maintaining the barrier-forming property of TIGHT JUNCTIONS. Claudin-4 is found associated with CLAUDIN-8 in the KIDNEY COLLECTING DUCT where it may play a role in paracellular chloride ion reabsorption.
] |
|
Claudin-5
|
D062507 |
[A claudin subtype that is found localized to TIGHT JUNCTIONS in VASCULAR ENDOTHELIAL CELLS. The protein was initially identified as one of several proteins which are deleted in VELOCARDIOFACIAL SYNDROME and may play an important role in maintaining the integrity of the BLOOD-BRAIN BARRIER.
] |
|
Claudins
|
D057167 |
[A large family of transmembrane proteins found in TIGHT JUNCTIONS. They take part in the formation of paracellular barriers and pores that regulate paracellular permeability.
] |
|
Clausena
|
D054700 |
[A plant genus of the family RUTACEAE. Members contain anethole and CARBAZOLES.
] |
|
Claustrum
|
D000079482 |
[A gray matter lamina located underneath the inner NEOCORTEX lateral to the PUTAMEN and medial to the INSULAR CORTEX. It is considered to be a part of the basal ganglia. Extensive claustral projections exist to most cortices and subcortical structures including the AMYGDALA, the CAUDATE NUCLEUS, the HIPPOCAMPUS and the THALAMUS.
] |
|
Clavibacter
|
D000086162 |
[A genus of high GC content, Gram-positive aerobic bacteria in the family Microbacteriaceae and phylum ACTINOBACTERIA. This genus contains some phytopathogenic coryneform (club-shaped) bacteria causing stunting diseases in plants.
] |
|
Claviceps
|
D002967 |
[A genus of ascomycetous fungi, family Clavicipitaceae, order Hypocreales, parasitic on various grasses (POACEAE). The sclerotia contain several toxic alkaloids. Claviceps purpurea on rye causes ergotism.
] |
|
Clavicle
|
D002968 |
[A bone on the ventral side of the shoulder girdle, which in humans is commonly called the collar bone.
] |
