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Choriocarcinoma, Non-gestational
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D031954 |
[A highly malignant CHORIOCARCINOMA derived from the non-placental origin such as the totipotent cells in the TESTIS, the OVARY, and the PINEAL GLAND. It produces high levels of CHORIONIC GONADOTROPIN and can metastasize widely through the bloodstream to the lungs, brain, liver, bone, and other viscera by the time of diagnosis.
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Chorion
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D002823 |
[The outermost extra-embryonic membrane surrounding the developing embryo. In REPTILES and BIRDS, it adheres to the shell and allows exchange of gases between the egg and its environment. In MAMMALS, the chorion evolves into the fetal contribution of the PLACENTA.
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Chorionic Gonadotropin
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D006063 |
[A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).
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Chorionic Gonadotropin, beta Subunit, Human
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D018997 |
[The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LUTEINIZING HORMONE, except for the additional 30 amino acids at the carboxy end with the associated carbohydrate residues. HCG-beta is used as a diagnostic marker for early detection of pregnancy, spontaneous abortion (ABORTION, SPONTANEOUS); ECTOPIC PREGNANCY; HYDATIDIFORM MOLE; CHORIOCARCINOMA; or DOWN SYNDROME.
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Chorionic Villi
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D002824 |
[Chorionic villi equivalent in lower mammals (e.g., mouse and rat)
, Threadlike vascular projections of the chorion. Chorionic villi may be free or embedded within the DECIDUA forming the site for exchange of substances between fetal and maternal blood (PLACENTA).
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Chorionic Villi Sampling
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D015193 |
[A method for diagnosis of fetal diseases by sampling the cells of the placental chorionic villi for DNA analysis, presence of bacteria, concentration of metabolites, etc. The advantage over amniocentesis is that the procedure can be carried out in the first trimester.
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Chorioretinitis
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D002825 |
[Inflammation of the choroid in which the sensory retina becomes edematous and opaque. The inflammatory cells and exudate may burst through the sensory retina to cloud the vitreous body.
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Chorismate Mutase
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D002826 |
[An isomerase that catalyzes the conversion of chorismic acid to prephenic acid. EC 5.4.99.5.
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Chorismic Acid
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D002827 |
[A cyclohexadiene carboxylic acid derived from SHIKIMIC ACID and a precursor for the biosynthesis of UBIQUINONE and the AROMATIC AMINO ACIDS.
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Choristoma
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D002828 |
[A mass of histologically normal tissue present in an abnormal location.
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Choroid
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D002829 |
[The thin, highly vascular membrane covering most of the posterior of the eye between the RETINA and SCLERA.
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Choroid Diseases
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D015862 |
[Disorders of the choroid including hereditary choroidal diseases, neoplasms, and other abnormalities of the vascular layer of the uvea.
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Choroid Hemorrhage
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D002832 |
[Hemorrhage from the vessels of the choroid.
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Choroid Neoplasms
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D002830 |
[Tumors of the choroid; most common intraocular tumors are malignant melanomas of the choroid. These usually occur after puberty and increase in incidence with advancing age. Most malignant melanomas of the uveal tract develop from benign melanomas (nevi).
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Choroid Plexus
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D002831 |
[A villous structure of tangled masses of BLOOD VESSELS contained within the third, lateral, and fourth ventricles of the BRAIN. It regulates part of the production and composition of CEREBROSPINAL FLUID.
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Choroid Plexus Neoplasms
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D016545 |
[Benign or malignant tumors which arise from the choroid plexus of the ventricles of the brain. Papillomas (see PAPILLOMA, CHOROID PLEXUS) and carcinomas are the most common histologic subtypes, and tend to seed throughout the ventricular and subarachnoid spaces. Clinical features include headaches, ataxia and alterations of consciousness, primarily resulting from associated HYDROCEPHALUS. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2072; J Neurosurg 1998 Mar;88(3):521-8)
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Choroidal Effusions
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D000080324 |
[Separation of the CHOROID from the SCLERA.
, Space created between the CHOROID and the SCLERA due to choroidal detachment.
, Finding of fluid accumulation between the CHOROID and the SCLERA.
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Choroidal Neovascularization
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D020256 |
[A pathological process consisting of the formation of new blood vessels in the CHOROID.
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Choroideremia
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D015794 |
[An X chromosome-linked abnormality characterized by atrophy of the choroid and degeneration of the retinal pigment epithelium causing night blindness.
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Choroiditis
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D002833 |
[Inflammation of the choroid.
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