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CD55 Antigens
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D018958 |
[GPI-linked membrane proteins broadly distributed among hematopoietic and non-hematopoietic cells. CD55 prevents the assembly of C3 CONVERTASE or accelerates the disassembly of preformed convertase, thus blocking the formation of the membrane attack complex.
] |
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CD56 Antigen
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D019002 |
[The 140 kDa isoform of NCAM (neural cell adhesion molecule) containing a transmembrane domain and short cytoplasmic tail. It is expressed by all lymphocytes mediating non-MHC restricted cytotoxicity and is present on some neural tissues and tumors.
] |
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CD57 Antigens
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D018959 |
[Oligosaccharide antigenic determinants found principally on NK CELLS and T-CELLS. They are expressed at high levels in terminally differentiated or senescent cells with reduced proliferative capacity; however, their role in the immune response is poorly understood.
] |
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CD58 Antigens
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D018968 |
[Glycoproteins with a wide distribution on hematopoietic and non-hematopoietic cells and strongly expressed on MACROPHAGES. CD58 mediates cell adhesion by binding to CD2; (CD2 ANTIGENS); and this enhances antigen-specific T-cell activation.
] |
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CD59 Antigens
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D018957 |
[Small glycoproteins found on both hematopoietic and non-hematopoietic cells. CD59 restricts the cytolytic activity of homologous complement by binding to C8 and C9 and blocking the assembly of the membrane attack complex. (From Barclay et al., The Leukocyte Antigen FactsBook, 1993, p234)
] |
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CD79 Antigens
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D051925 |
[Components of the B-cell antigen receptor that function in B-cell antigen receptor heavy chain transport to the PLASMA MEMBRANE. They are expressed almost exclusively by B-LYMPHOCYTES and are markers for B-cell NEOPLASMS.
] |
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CD8 Antigens
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D016827 |
[Differentiation antigens found on thymocytes and on cytotoxic and suppressor T-lymphocytes. T8 antigens are members of the immunoglobulin supergene family and are associative recognition elements in MHC (Major Histocompatibility Complex) Class I-restricted interactions.
] |
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CD8-Positive T-Lymphocytes
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D018414 |
[A critical subpopulation of regulatory T-lymphocytes involved in MHC Class I-restricted interactions. They include both cytotoxic T-lymphocytes (T-LYMPHOCYTES, CYTOTOXIC) and CD8+ suppressor T-lymphocytes.
] |
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CDC2 Protein Kinase
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D016203 |
[Phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the CELL CYCLE. It is the catalytic subunit of the MATURATION-PROMOTING FACTOR and complexes with both CYCLIN A and CYCLIN B in mammalian cells. The maximal activity of cyclin-dependent kinase 1 is achieved when it is fully dephosphorylated.
] |
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CDC2-CDC28 Kinases
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D042846 |
[A family of cell cycle-dependent kinases that are related in structure to CDC28 PROTEIN KINASE, S CEREVISIAE and the CDC2 PROTEIN KINASE found in mammalian species.
] |
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CDC28 Protein Kinase, S cerevisiae
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D017489 |
[A protein kinase encoded by the Saccharomyces cerevisiae CDC28 gene and required for progression from the G1 PHASE to the S PHASE in the CELL CYCLE.
] |
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CDP-Diacylglycerol-Inositol 3-Phosphatidyltransferase
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D051607 |
[An enzyme that catalyzes the formation of PHOSPHATIDYLINOSITOL and CMP from CDP-DIACYLGLYCEROL and MYOINOSITOL.
] |
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CDPdiacylglycerol-Serine O-Phosphatidyltransferase
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D010717 |
[An enzyme that catalyzes the formation of phosphatidylserine and CMP from CDPdiglyceride plus serine. EC 2.7.8.8.
] |
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CDX2 Transcription Factor
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D000071616 |
[An antennapedia-like homeodomain transcription factor that regulates the expression of multiple genes in the INTESTINAL MUCOSA. It plays a critical role in many processes from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.
] |
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CELF Proteins
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D000067878 |
[A family of RRM proteins which contain two N-terminal RNA RECOGNITION MOTIF (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 amino acids between the second and third RRM domains. They regulate pre-mRNA ALTERNATIVE SPLICING and also function in RNA EDITING and PROTEIN BIOSYNTHESIS.
] |
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CELF1 Protein
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D000067879 |
[A member of the CELF PROTEINS family which binds GU rich elements (GREs) and CUG-triplet repeats in the 3'UTR of mammalian mRNA transcripts that undergo rapid turnover. It also binds AU-rich elements (AREs or EDEN-like) in the 3'UTR of JUN and FOS mRNAs. Mutations in the human CELF1 gene are associated with MYOTONIC DYSTROPHY type 1.
] |
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CHARGE Syndrome
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D058747 |
[Rare disease characterized by COLOBOMA; CHOANAL ATRESIA; and abnormal SEMICIRCULAR CANALS. Mutations in CHD7 protein resulting in disturbed neural crest development are associated with CHARGE Syndrome.
] |
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CHO Cells
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D016466 |
[CELL LINE derived from the ovary of the Chinese hamster, Cricetulus griseus (CRICETULUS). The species is a favorite for cytogenetic studies because of its small chromosome number. The cell line has provided model systems for the study of genetic alterations in cultured mammalian cells.
] |
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CLOCK Proteins
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D056926 |
[Basic helix-loop-helix (bHLH) domain-containing proteins that contain intrinsic HISTONE ACETYLTRANSFERASE activity and play important roles in CIRCADIAN RHYTHM regulation. Clock proteins combine with Arntl proteins to form heterodimeric transcription factors that are specific for E-BOX ELEMENTS and stimulate the transcription of several E-box genes that are involved in cyclical regulation. This transcriptional activation also sets into motion a time-dependent feedback loop which in turn down-regulates the expression of clock proteins.
] |
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CME-Carbodiimide
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D003028 |
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