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Zinc Finger E-box-Binding Homeobox 1
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D000071799 |
[A transcription factor characterized by N-terminal and C-terminal CYS2-HIS2 ZINC FINGERS separated by a homeobox. It represses the expression of E-CADHERIN to induce the EPITHELIAL-MESENCHYMAL TRANSITION. It also represses PROTO-ONCOGENE PROTEINS C-BCL-6; regulates the cell type-specific expression of SODIUM-POTASSIUM-EXCHANGING ATPASE; and promotes neuronal differentiation.
] |
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Zinc Finger Nucleases
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D000075804 |
[Genetically engineered nucleases that cleave DNA at a defined distance from specific DNA sequences recognized by ZINC FINGER DNA-BINDING DOMAINS. They are composed of a DNA cleaving domain adapted from DNA endonucleases fused to a zinc finger DNA-binding domain.
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Zinc Finger Protein GLI1
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D000071676 |
[A transcriptional activator and oncogene protein that contains two CYS2-HIS2 ZINC FINGERS. Two isoforms are expressed; both regulate the expression of specific genes during development of craniofacial features, digits, the CENTRAL NERVOUS SYSTEM; and the GASTROINTESTINAL TRACT. They also regulate SONIC HEDGEHOG PROTEIN signaling and cell proliferation.
] |
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Zinc Finger Protein Gli2
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D000075746 |
[A transcriptional activator that contains five adjacent CYS2-HIS2 ZINC FINGERS. It functions in the hedgehog signaling pathway and is required for normal embryonic development. Mutations in the GLI2 gene are associated with type 9 HOLOPROSENCEPHALY and type 2 PALLISTER-HALL SYNDROME.
] |
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Zinc Finger Protein Gli3
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D000074290 |
[A zinc finger transcription factor that contains five CYS2-HIS2 ZINC FINGERS and binds to the GLI consensus sequence 5'-GGGTGGTC-3'. The full-length protein functions as a transcriptional activator whereas the truncated C-terminal form functions as a transcriptional repressor of the Sonic Hedgehog (Shh) signaling pathway; a balance between these two forms is critical for limb and digit development. GLI3 also plays a critical role in the differentiation and proliferation of CHONDROCYTES.
] |
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Zinc Fingers
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D016335 |
[Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger, one zinc atom is bound to two cysteines and two histidines. In between the cysteines and histidines are 12 residues which form a DNA binding fingertip. By variations in the composition of the sequences in the fingertip and the number and spacing of tandem repeats of the motif, zinc fingers can form a large number of different sequence specific binding sites.
] |
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Zinc Isotopes
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D015033 |
[Stable zinc atoms that have the same atomic number as the element zinc, but differ in atomic weight. Zn-66-68, and 70 are stable zinc isotopes.
] |
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Zinc Oxide
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D015034 |
[A mild astringent and topical protectant with some antiseptic action. It is also used in bandages, pastes, ointments, dental cements, and as a sunblock.
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Zinc Oxide-Eugenol Cement
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D015035 |
[Used as a dental cement this is mainly zinc oxide (with strengtheners and accelerators) and eugenol. (Boucher's Clinical Dental Terminology, 4th ed, p50)
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Zinc Phosphate Cement
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D015036 |
[A material used for cementation of inlays, crowns, bridges, and orthodontic appliances and occasionally as a temporary restoration. It is prepared by mixing zinc oxide and magnesium oxide powders with a liquid consisting principally of phosphoric acid, water, and buffers. (From Bouchers' Clinical Dental Terminology, 3d ed)
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Zinc Radioisotopes
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D015037 |
[Unstable isotopes of zinc that decay or disintegrate emitting radiation. Zn atoms with atomic weights 60-63, 65, 69, 71, and 72 are radioactive zinc isotopes.
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Zinc Sulfate
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D019287 |
[A compound given in the treatment of conditions associated with zinc deficiency such as acrodermatitis enteropathica. Externally, zinc sulfate is used as an astringent in lotions and eye drops. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)
] |
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Zinc Transporter 8
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D000075703 |
[A zinc efflux transporter highly expressed by ISLET CELLS of the pancreas. It functions in the accumulation of zinc in intracellular vesicles and may be involved in INSULIN maturation and storage processes. Variations in the SLC30A8 gene are associated with susceptibility to DIABETES MELLITUS, TYPE 2.
] |
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Zineb
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D015038 |
[An agricultural fungicide of the dithiocarbamate class. It has relatively low toxicity and there is little evidence of human injury from exposure.
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Zingiberaceae
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D030521 |
[A plant family of the order Zingiberales, subclass Zingiberidae, class Liliopsida. It includes plants which have both flavoring and medicinal properties such as GINGER; turmeric (CURCUMA), and cardamom (ELETTARIA).
, A plant genus. The root used in Thai cooking. Members contain CHALCONES.
] |
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Zingiberales
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D019862 |
[An order of herbaceous tropical perennials which include the banana (MUSACEAE) and GINGER (ZINGIBERACEAE) family.
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Zinostatin
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D009353 |
[An enediyne that alkylates DNA and RNA like MITOMYCIN does, so it is cytotoxic.
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Ziram
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D015039 |
[An industrial fungicide with low mammalian toxicity, although it does possess an irritant capacity for skin and mucous membranes.
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Zirconium
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D015040 |
[A rather rare metallic element with atomic number 40, atomic weight 91.224, and symbol Zr.
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Ziziphus
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D031957 |
[A plant genus of the family RHAMNACEAE. Members contain nummularogenin (a spirostane) and is the source of an edible fruit.
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