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Viper Venoms
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D014757 |
[Venoms from SNAKES of the viperid family. They tend to be less toxic than elapid or hydrophid venoms and act mainly on the vascular system, interfering with coagulation and capillary membrane integrity and are highly cytotoxic. They contain large amounts of several enzymes, other factors, and some toxins.
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Viperidae
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D017819 |
[A family of snakes comprising four subfamilies: Azemiopinae (the mountain viper, the sole member of this subfamily), Viperinae (true vipers), Crotalinae (pit vipers) and Causinae. They are widespread throughout the world, being found in the United States, Central and South America, Europe, Asia and Africa. Their venoms act on the blood (hemotoxic) as compared to the venom of elapids which act on the nervous system (neurotoxic). (Goin, Goin, and Zug, Introduction to Herpetology, 3d ed, pp333-36)
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Vipoma
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D003969 |
[A tumor that secretes VASOACTIVE INTESTINAL PEPTIDE, a neuropeptide that causes VASODILATION; relaxation of smooth muscles; watery DIARRHEA; HYPOKALEMIA; and HYPOCHLORHYDRIA. Vipomas, derived from the pancreatic ISLET CELLS, generally are malignant and can secrete other hormones. In most cases, Vipomas are located in the PANCREAS but can be found in extrapancreatic sites.
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Viral Core Proteins
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D014758 |
[Proteins found mainly in icosahedral DNA and RNA viruses. They consist of proteins directly associated with the nucleic acid inside the NUCLEOCAPSID.
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Viral Envelope
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D000086942 |
[Bilayer lipid membrane acquired by VIRAL PARTICLES during VIRAL MORPHOGENESIS. Although the LIPIDS of the viral envelope are host derived, various virus-encoded INTEGRAL MEMBRANE PROTEINS, i.e. VIRAL ENVELOPE PROTEINS are incorporated there.
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Viral Envelope Proteins
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D014759 |
[Integral membrane proteins that are incorporated into the VIRAL ENVELOPE. They are glycosylated during VIRAL ASSEMBLY.
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Viral Fusion Protein Inhibitors
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D065147 |
[Drugs that are designed to block the action of VIRAL FUSION PROTEINS and prevent VIRUSES from entering the cell.
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Viral Fusion Proteins
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D014760 |
[Proteins, usually glycoproteins, found in the viral envelopes of a variety of viruses. They promote cell membrane fusion and thereby may function in the uptake of the virus by cells.
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Viral Genome Packaging
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D000086482 |
[Folding of the viral genomic nucleic acid into the VIRUS PARTICLE.
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Viral Hepatitis Vaccines
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D014761 |
[Any vaccine raised against any virus or viral derivative that causes hepatitis.
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Viral Interference
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D014762 |
[A phenomenon in which infection by a first virus results in resistance of cells or tissues to infection by a second, unrelated virus.
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Viral Load
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D019562 |
[The quantity of measurable virus in a body fluid. Change in viral load, measured in plasma, is sometimes used as a SURROGATE MARKER in disease progression.
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Viral Matrix Proteins
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D014763 |
[Proteins associated with the inner surface of the lipid bilayer of the viral envelope. These proteins have been implicated in control of viral transcription and may possibly serve as the "glue" that binds the nucleocapsid to the appropriate membrane site during viral budding from the host cell.
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Viral Nonstructural Proteins
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D017361 |
[Proteins encoded by a VIRAL GENOME that are not structural components of VIRUS PARTICLES. Some of these proteins may play roles within the infected cell during VIRUS REPLICATION or act in regulation of virus replication or VIRUS ASSEMBLY.
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Viral Packaging Sequence
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D000086502 |
[Specific sequences in the viral nucleic acid that are involved in packaging the viral genome (VIRAL GENOME PACKAGING) into the VIRUS PARTICLES.
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Viral Papain-like Proteases
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D000086062 |
[A subclass of cysteine endopeptidases found in VIRUSES that share structural similarities with PAPAIN.
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Viral Plaque Assay
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D010948 |
[Method for measuring viral infectivity and multiplication in CULTURED CELLS. Clear lysed areas or plaques develop as the VIRAL PARTICLES are released from the infected cells during incubation. With some VIRUSES, the cells are killed by a cytopathic effect; with others, the infected cells are not killed but can be detected by their hemadsorptive ability. Sometimes the plaque cells contain VIRAL ANTIGENS which can be measured by IMMUNOFLUORESCENCE.
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Viral Protease Inhibitors
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D000084762 |
[Compounds that specifically inhibit PROTEOLYTIC ENZYMES that are encoded by VIRUSES.
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Viral Proteases
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D000085242 |
[A broad category of proteolytic enzymes that are produced by VIRUSES. They play a role in the viral life cycle by processing viral proteins and possibly acting on host cell proteins.
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Viral Proteins
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D014764 |
[Proteins found in any species of virus.
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