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Trypsin Inhibitor, Kazal Pancreatic
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D014359 |
[A secreted KAZAL MOTIF-containing serine peptidase inhibitor that inhibits TRYPSIN. It is a protein composed of 56 amino acid residues and is different in amino acid composition and physiological activity from the Kunitz bovine pancreatic trypsin inhibitor (APROTININ). It protects against the trypsin-mediated premature activation of ENZYME PRECURSORS in the PANCREAS. Mutations in the SPINK1 gene are associated with CHRONIC PANCREATITIS.
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Trypsin Inhibitor, Kunitz Soybean
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D014360 |
[A high-molecular-weight protein (approximately 22,500) containing 198 amino acid residues. It is a strong inhibitor of trypsin and human plasmin.
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Trypsin Inhibitors
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D014361 |
[Serine proteinase inhibitors which inhibit trypsin. They may be endogenous or exogenous compounds.
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Trypsinogen
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D014362 |
[The inactive proenzyme of trypsin secreted by the pancreas, activated in the duodenum via cleavage by enteropeptidase. (Stedman, 25th ed)
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Tryptamines
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D014363 |
[Derivatives of TRYPTAMINES that are SEROTONIN RECEPTOR AGONISTS acting at 5-HT1 RECEPTORS. Some are used to treat MIGRAINE DISORDERS.
, Decarboxylated monoamine derivatives of TRYPTOPHAN.
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Tryptases
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D053802 |
[A family of neutral serine proteases with TRYPSIN-like activity. Tryptases are primarily found in the SECRETORY GRANULES of MAST CELLS and are released during mast cell degranulation.
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Tryptophan
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D014364 |
[An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.
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Tryptophan Hydroxylase
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D014365 |
[An enzyme that catalyzes the hydroxylation of TRYPTOPHAN to 5-HYDROXYTRYPTOPHAN in the presence of NADPH and molecular oxygen. It is important in the biosynthesis of SEROTONIN.
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Tryptophan Oxygenase
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D014366 |
[A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is a LIVER-specific enzyme that is the first and rate limiting enzyme in the kynurenine pathway of TRYPTOPHAN catabolism.
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Tryptophan Synthase
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D014367 |
[An enzyme that catalyzes the conversion of L-serine and 1-(indol-3-yl)glycerol 3-phosphate to L-tryptophan and glyceraldehyde 3-phosphate. It is a pyridoxal phosphate protein that also catalyzes the conversion of serine and indole into tryptophan and water and of indoleglycerol phosphate into indole and glyceraldehyde phosphate. (From Enzyme Nomenclature, 1992) EC 4.2.1.20.
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Tryptophan Transaminase
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D051279 |
[A PYRIDOXAL PHOSPHATE containing enzyme that catalyzes the transfer amino group from L-TRYPTOPHAN to 2-oxoglutarate in order to generate indolepyruvate and L-GLUTAMATE.
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Tryptophan-tRNA Ligase
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D014369 |
[An enzyme that activates tryptophan with its specific transfer RNA. EC 6.1.1.2.
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Tryptophanase
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D014368 |
[An enzyme that catalyzes the conversion of L-tryptophan and water to indole, pyruvate, and ammonia. It is a pyridoxal-phosphate protein, requiring K+. It also catalyzes 2,3-elimination and beta-replacement reactions of some indole-substituted tryptophan analogs of L-cysteine, L-serine, and other 3-substituted amino acids. (From Enzyme Nomenclature, 1992) EC 4.1.99.1.
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Tsetse Flies
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D014370 |
[Bloodsucking flies of the genus Glossina, found primarily in equatorial Africa. Several species are intermediate hosts of trypanosomes.
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Tsuga
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D028225 |
[A plant genus in the family PINACEAE, order Pinales, class Pinopsida, division Coniferophyta. They are coniferous evergreen trees and should not be confused with hemlock plants (CICUTA and CONIUM).
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Tsunamis
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D057192 |
[Series of ocean waves produced by geologic events or underwater LANDSLIDES. These waves can travel at speeds averaging 450 (and up to 600) miles per hour in the open ocean.
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Tuber Cinereum
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D014371 |
[Layer of GRAY MATTER in the HYPOTHALAMUS that also forms part of the floor of the THIRD VENTRICLE and merges anteriorly into the infundibulum (see PITUITARY GLAND, POSTERIOR).
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Tubercidin
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D014372 |
[An antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids.
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Tuberculin
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D014373 |
[A protein extracted from boiled culture of tubercle bacilli (MYCOBACTERIUM TUBERCULOSIS). It is used in the tuberculin skin test (TUBERCULIN TEST) for the diagnosis of tuberculosis infection in asymptomatic persons.
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Tuberculin Test
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D014374 |
[One of several skin tests to determine past or present tuberculosis infection. A purified protein derivative of the tubercle bacilli, called tuberculin, is introduced into the skin by scratch, puncture, or interdermal injection.
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