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Trichothecenes, Type C
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D000081443 |
[A subclass of Trichothecene derivatives that includes the 12,13-epoxytrichothec-9-ene structure with an epoxide oxygen bond to the C7 and C8 carbon atoms.
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Trichothiodystrophy Syndromes
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D054463 |
[Autosomal recessive neuroectodermal disorders characterized by brittle sulfur-deficient hair associated with impaired intellect, decreased fertility, and short stature. It may include nail dystrophy, ICHTHYOSIS, and photosensitivity correlated with a NUCLEOTIDE EXCISION REPAIR defect. All individuals with this disorder have a deficiency of cysteine-rich KERATIN-ASSOCIATED PROTEINS found in the interfilamentous matrix. Photosensitive trichothiodystrophy can be caused by mutation in at least 2 separate genes: ERCC2 PROTEIN gene and the related ERCC3. Nonphotosensitive trichothiodystrophy can be caused by mutation in the TTDN1 gene.
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Trichotillomania
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D014256 |
[Compulsion to pull out one's hair.
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Trichuriasis
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D014257 |
[Infection with nematodes of the genus TRICHURIS, formerly called Trichocephalus.
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Trichuris
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D014258 |
[A genus of nematode worms comprising the whipworms.
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Trichuroidea
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D014259 |
[A superfamily of nematodes of the order ENOPLIDA. Its organisms have a well developed intestine and rectum.
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Triclabendazole
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D000077682 |
[Benzimidazole antiplatyhelmintic agent that is used for the treatment of FASCIOLIASIS and PARAGONIMIASIS.
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Triclosan
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D014260 |
[A diphenyl ether derivative used in cosmetics and toilet soaps as an antiseptic. It has some bacteriostatic and fungistatic action.
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Tricuspid Atresia
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D018785 |
[Absence of the orifice between the RIGHT ATRIUM and RIGHT VENTRICLE, with the presence of an atrial defect through which all the systemic venous return reaches the left heart. As a result, there is left ventricular hypertrophy (HYPERTROPHY, LEFT VENTRICULAR) because the right ventricle is absent or not functional.
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Tricuspid Valve
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D014261 |
[The valve consisting of three cusps situated between the right atrium and right ventricle of the heart.
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Tricuspid Valve Insufficiency
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D014262 |
[Backflow of blood from the RIGHT VENTRICLE into the RIGHT ATRIUM due to imperfect closure of the TRICUSPID VALVE.
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Tricuspid Valve Prolapse
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D014263 |
[Abnormal protrusion of one or more of the leaflets of TRICUSPID VALVE into the RIGHT ATRIUM during SYSTOLE. This allows the backflow of blood into right atrium leading to TRICUSPID VALVE INSUFFICIENCY; SYSTOLIC MURMURS. Its most common cause is not primary valve abnormality but rather the dilation of the RIGHT VENTRICLE and the tricuspid annulus.
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Tricuspid Valve Stenosis
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D014264 |
[The pathologic narrowing of the orifice of the TRICUSPID VALVE. This hinders the emptying of RIGHT ATRIUM leading to elevated right atrial pressure and systemic venous congestion. Tricuspid valve stenosis is almost always due to RHEUMATIC FEVER.
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Trientine
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D014266 |
[An ethylenediamine derivative used as stabilizer for EPOXY RESINS, as ampholyte for ISOELECTRIC FOCUSING and as chelating agent for copper in HEPATOLENTICULAR DEGENERATION.
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Triethylenemelamine
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D014265 |
[Toxic alkylating agent used in industry; also as antineoplastic and research tool to produce chromosome aberrations and cancers.
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Triethylenephosphoramide
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D013721 |
[An insect chemosterilant and an antineoplastic agent.
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Triethyltin Compounds
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D014267 |
[Organic compounds composed of tin and three ethyl groups. Affect mitochondrial metabolism and inhibit oxidative phosphorylation by acting directly on the energy conserving processes.
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Trifluoperazine
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D014268 |
[A phenothiazine with actions similar to CHLORPROMAZINE. It is used as an antipsychotic and an antiemetic.
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Trifluoroacetic Acid
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D014269 |
[A very strong halogenated derivative of acetic acid. It is used in acid catalyzed reactions, especially those where an ester is cleaved in peptide synthesis.
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Trifluoroethanol
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D014270 |
[A non-aqueous co-solvent that serves as tool to study protein folding. It is also used in various pharmaceutical, chemical and engineering applications.
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