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Testicular Diseases
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D013733 |
[Pathological processes of the TESTIS.
] |
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Testicular Hormones
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D013735 |
[Hormones produced in the testis.
] |
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Testicular Hydrocele
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D006848 |
[Accumulation of serous fluid between the layers of membrane (tunica vaginalis) covering the TESTIS in the SCROTUM.
] |
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Testicular Neoplasms
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D013736 |
[Tumors or cancer of the TESTIS. Germ cell tumors (GERMINOMA) of the testis constitute 95% of all testicular neoplasms.
] |
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Testis
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D013737 |
[The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.
] |
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Testolactone
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D013738 |
[An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer.
] |
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Testosterone
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D013739 |
[A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
, Unlike testosterone, which is a flat molecule, its 8-isomer has a folded conformation.
] |
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Testosterone Congeners
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D045165 |
[Steroidal compounds related to TESTOSTERONE, the major mammalian male sex hormone. Testosterone congeners include important testosterone precursors in the biosynthetic pathways, metabolites, derivatives, and synthetic steroids with androgenic activities.
] |
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Testosterone Propionate
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D043343 |
[An ester of TESTOSTERONE with a propionate substitution at the 17-beta position.
] |
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Tetanus
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D013742 |
[A disease caused by tetanospasmin, a powerful protein toxin produced by CLOSTRIDIUM TETANI. Tetanus usually occurs after an acute injury, such as a puncture wound or laceration. Generalized tetanus, the most common form, is characterized by tetanic muscular contractions and hyperreflexia. Localized tetanus presents itself as a mild condition with manifestations restricted to muscles near the wound. It may progress to the generalized form.
] |
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Tetanus Antitoxin
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D013743 |
[An antitoxin used for the treatment of TETANUS.
] |
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Tetanus Toxin
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D013744 |
[Protein synthesized by CLOSTRIDIUM TETANI as a single chain of ~150 kDa with 35% sequence identity to BOTULINUM TOXIN that is cleaved to a light and a heavy chain that are linked by a single disulfide bond. Tetanolysin is the hemolytic and tetanospasmin is the neurotoxic principle. The toxin causes disruption of the inhibitory mechanisms of the CNS, thus permitting uncontrolled nervous activity, leading to fatal CONVULSIONS.
] |
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Tetanus Toxoid
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D013745 |
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Tetany
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D013746 |
[A disorder characterized by muscle twitches, cramps, and carpopedal spasm, and when severe, laryngospasm and seizures. This condition is associated with unstable depolarization of axonal membranes, primarily in the peripheral nervous system. Tetany usually results from HYPOCALCEMIA or reduced serum levels of MAGNESIUM that may be associated with HYPERVENTILATION; HYPOPARATHYROIDISM; RICKETS; UREMIA; or other conditions. (From Adams et al., Principles of Neurology, 6th ed, p1490)
] |
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Tetrabenazine
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D013747 |
[A drug formerly used as an antipsychotic and treatment of various movement disorders. Tetrabenazine blocks neurotransmitter uptake into adrenergic storage vesicles and has been used as a high affinity label for the vesicle transport system.
] |
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Tetracaine
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D013748 |
[A potent local anesthetic of the ester type used for surface and spinal anesthesia.
] |
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Tetrachloroethylene
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D013750 |
[A chlorinated hydrocarbon used as an industrial solvent and cooling liquid in electrical transformers. It is a potential carcinogen.
] |
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Tetrachlorvinphos
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D013751 |
[An organophosphate cholinesterase inhibitor that is used as an insecticide. It has low mammalian toxicity. (From Merck Index, 11th ed)
] |
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Tetracycline
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D013752 |
[A naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis.
] |
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Tetracycline Resistance
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D013753 |
[Nonsusceptibility of bacteria to the action of TETRACYCLINE which inhibits aminoacyl-tRNA binding to the 30S ribosomal subunit during protein synthesis.
] |
