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Spasms, Infantile
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D013036 |
[An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8)
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Spastic Paraplegia, Hereditary
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D015419 |
[A group of inherited diseases that share similar phenotypes but are genetically diverse. Different genetic loci for autosomal recessive, autosomal dominant, and x-linked forms of hereditary spastic paraplegia have been identified. Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity. Peripheral sensory neurons may be affected in the later stages of the disease. (J Neurol Neurosurg Psychiatry 1998 Jan;64(1):61-6; Curr Opin Neurol 1997 Aug;10(4):313-8)
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Spastin
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D000074181 |
[An AAA ATPase that binds and severs MICROTUBULES. It specifically recognizes and cuts polyglutamylated microtubules with short polyglutamate tails to promote reorganization of cellular microtubule arrays and the release of microtubules from the CENTROSOME following nucleation. It is critical for the biogenesis and maintenance of complex microtubule arrays in AXONS; SPINDLE APPARATUS; and CILIA. Mutations in the spastin gene (SPAST) are associated with type 4 of HEREDITARY SPASTIC PARAPLEGIA.
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Spatial Analysis
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D062206 |
[Investigative techniques which measure the topological, geometric, and or geographic properties of the entities studied.
, A weighted, moving-average estimation technique based on geostatistics that uses the spatial correlation of point measurements to estimate values at adjacent, unmeasured points. http://www.epa.gov/emap/html/pubs/docs/resdocs/mglossary.html#kk (Oct. 18,2011)
, The degree of interdependence among data arranged on a three-dimensional grid. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
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Spatial Behavior
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D013037 |
[Reactions of an individual or groups of individuals with relation to the immediate surrounding area including the animate or inanimate objects within that area.
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Spatial Learning
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D065853 |
[A process through which individuals encode information about their environmental CUES to facilitate SPATIAL NAVIGATION.
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Spatial Memory
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D065852 |
[Memory related to spatial information.
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Spatial Navigation
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D065854 |
[Process by which organisms use various cues to develop a route to a destination and their ability to travel such a planned route.
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Spatial Processing
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D065855 |
[Integration of spatial information perceived by visual and/or auditory CUES.
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Spatial Regression
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D000068916 |
[Methods used to take into account and incorporate spatial autocorrelation and regional variation into regression analysis models of data that has spatial dependency, and also to provide information on the spatial relationships among the variables.
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Spatio-Temporal Analysis
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D062211 |
[Techniques which study entities using their topological, geometric, or geographic properties and include the dimension of time in the analysis.
, The study of spatial location of entities over time.
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Specialization
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D013038 |
[The limitation of practice or study to a particular branch of medicine, dentistry, or other health profession. It is philosophically distinct from the generalist theory in which familiarity with a wide cross-section of the particular discipline is advocated.
, An occupation limited in scope to a subsection of a broader field.
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Specialties, Dental
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D013039 |
[Various branches of dental practice limited to specialized areas.
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Specialties, Nursing
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D013041 |
[Various branches of nursing practice limited to specialized areas.
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Specialties, Surgical
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D013043 |
[Various branches of surgical practice limited to specialized areas.
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Specialty Boards
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D013044 |
[Organizations which certify physicians and dentists as specialists in various fields of medical and dental practice.
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Specialty Uses of Chemicals
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D020313 |
[Uses of chemicals in a research, industrial, or household setting. This does not include PHARMACOLOGIC ACTIONS.
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Species Specificity
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D013045 |
[The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
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Specific Gravity
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D013046 |
[The ratio of the density of a material to the density of some standard material, such as water or air, at a specified temperature.
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Specific Language Disorder
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D000080888 |
[Language disorder that delays the mastery of oral language skills or in children who have no hearing loss or other developmental delays.
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