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Sinus Pericranii
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D020779 |
[Rare vascular anomaly involving a communication between the intracranial and extracranial venous circulation via diploe, the central spongy layer of cranial bone. It is often characterized by dilated venous structures on the scalp due to abnormal drainage from the intracranial venous sinuses. Sinus pericranii can be congenital or traumatic in origin.
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Sinus Thrombosis, Intracranial
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D012851 |
[Formation or presence of a blood clot (THROMBUS) in the CRANIAL SINUSES, large endothelium-lined venous channels situated within the SKULL. Intracranial sinuses, also called cranial venous sinuses, include the superior sagittal, cavernous, lateral, petrous sinuses, and many others. Cranial sinus thrombosis can lead to severe HEADACHE; SEIZURE; and other neurological defects.
] |
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Sinus of Valsalva
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D012850 |
[The dilatation of the aortic wall behind each of the cusps of the aortic valve.
] |
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Sinusitis
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D012852 |
[Inflammation of the NASAL MUCOSA in one or more of the PARANASAL SINUSES.
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Siphonaptera
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D005423 |
[An order of parasitic, blood-sucking, wingless INSECTS with the common name of fleas.
] |
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Siphoviridae
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D017906 |
[A tentative species in the genus T5-like PHAGES.
, A genus in the family SIPHOVIRIDAE, characterized by virions with large heads and long, kinked tail fibers.
, A genus in the family SIPHOVIRIDAE. The DNA has cohesive ends and is packaged as a unit size filament.
, A family of BACTERIOPHAGES and ARCHAEAL VIRUSES which are characterized by long, non-contractile tails.
] |
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Sirenia
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D020453 |
[An order of heavy-bodied, slow-moving, completely aquatic, herbivorous mammals. The body is fusiform, plump, and hairless, except for bristles on the snout. Hindlimbs are absent, the forelimbs are modified to flippers, and the tail is a horizontal fluke. (From Scott, Concise Encyclopedia Biology, 1996)
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Sirolimus
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D020123 |
[A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.
] |
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Sirtuin 1
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D056564 |
[A sirtuin family member found primarily in the CELL NUCLEUS. It is an NAD-dependent deacetylase with specificity towards HISTONES and a variety of proteins involved in gene regulation.
] |
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Sirtuin 2
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D056565 |
[A sirtuin family member found primarily in the CYTOPLASM. It is a multifunctional enzyme that contains a NAD-dependent deacetylase activity that is specific for HISTONES and a mono-ADP-ribosyltransferase activity.
] |
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Sirtuin 3
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D056566 |
[A sirtuin family member found primarily in MITOCHONDRIA. It is a multifunctional enzyme that contains a NAD-dependent deacetylase activity that is specific for HISTONES and a mono-ADP-ribosyltransferase activity.
] |
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Sirtuins
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D037761 |
[A homologous family of regulatory enzymes that are structurally related to the protein silent mating type information regulator 2 (Sir2) found in Saccharomyces cerevisiae. Sirtuins contain a central catalytic core region which binds NAD. Several of the sirtuins utilize NAD to deacetylate proteins such as HISTONES and are categorized as GROUP III HISTONE DEACETYLASES. Several other sirtuin members utilize NAD to transfer ADP-RIBOSE to proteins and are categorized as MONO ADP-RIBOSE TRANSFERASES, while a third group of sirtuins appears to have both deacetylase and ADP ribose transferase activities.
] |
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Sisomicin
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D012853 |
[Antibiotic produced by Micromonospora inyoensis. It is closely related to gentamicin C1A, one of the components of the gentamicin complex (GENTAMICINS).
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Sister Chromatid Exchange
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D012854 |
[An exchange of segments between the sister chromatids of a chromosome, either between the sister chromatids of a meiotic tetrad or between the sister chromatids of a duplicated somatic chromosome. Its frequency is increased by ultraviolet and ionizing radiation and other mutagenic agents and is particularly high in BLOOM SYNDROME.
] |
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Sister Mary Joseph's Nodule
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D058288 |
[Metastatic lesion of the UMBILICUS associated with intra-abdominal neoplasms especially of the GASTROINTESTINAL TRACT or OVARY.
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Sitagliptin Phosphate
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D000068900 |
[A pyrazine-derived DIPEPTIDYL-PEPTIDASE IV INHIBITOR and HYPOGLYCEMIC AGENT that increases the levels of the INCRETIN hormones GLUCAGON-LIKE PEPTIDE-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). It is used in the treatment of TYPE 2 DIABETES.
] |
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Sitagliptin Phosphate, Metformin Hydrochloride Drug Combination
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D000068899 |
[A pharmaceutical preparation of sitagliptin phosphate and metformin hydrochloride that is used in the treatment of TYPE 2 DIABETES.
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Site-Specific DNA-Methyltransferase (Adenine-Specific)
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D015265 |
[An enzyme responsible for producing a species-characteristic methylation pattern on adenine residues in a specific short base sequence in the host cell DNA. The enzyme catalyzes the methylation of DNA adenine in the presence of S-adenosyl-L-methionine to form DNA containing 6-methylaminopurine and S-adenosyl-L-homocysteine. EC 2.1.1.72.
] |
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Site-Specific DNA-Methyltransferase (Cytosine-N4-Specific)
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D057265 |
[A DNA-methyltransferase that catalyzes the transfer of a methyl group from S-ADENOSYLMETHIONINE to the exocyclic NH2 group at the 4 position of CYTOSINE.
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Sitosterols
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D012855 |
[A family of sterols commonly found in plants and plant oils. Alpha-, beta-, and gamma-isomers have been characterized.
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