|
Pyrimidines
|
D011743 |
[A family of 6-membered heterocyclic compounds occurring in nature in a wide variety of forms. They include several nucleic acid constituents (CYTOSINE; THYMINE; and URACIL) and form the basic structure of the barbiturates.
] |
|
Pyrimidinones
|
D011744 |
[Heterocyclic compounds known as 2-pyrimidones (or 2-hydroxypyrimidines) and 4-pyrimidones (or 4-hydroxypyrimidines) with the general formula C4H4N2O.
] |
|
Pyrin
|
D000071198 |
[A tripartite motif protein that consists of an N-terminal pyrin domain, a central coiled-coil region and B-box type ZINC FINGER, and C-terminal regions that mediate homotrimerization and interactions with other proteins (the B30.2/SPRY DOMAIN). It is expressed primarily by mature GRANULOCYTES and associates with the cytoskeleton in the perinuclear area as well as AUTOPHAGOSOMES, where it co-ordinates the assembly of AUTOPHAGY-RELATED PROTEINS and degradation of INFLAMMASOME components. It functions in INNATE IMMUNITY and INFLAMMATION; mutations in the Pyrin protein (MEFV) gene are associated with FAMILIAL MEDITERRANEAN FEVER.
] |
|
Pyrin Domain
|
D000071196 |
[A protein interaction domain of the death domain superfamily. It is characterized by a 6-helix bundle similar to those that occur in DEATH DOMAIN RECEPTORS. Pyrin domains are present in a variety of proteins, especially those that function in INFLAMMASOMES; AUTOPHAGY; and APOPTOSIS. They form homodimers or heterodimers with death domain proteins to facilitate the assembly of signaling complexes.
] |
|
Pyrithiamine
|
D011745 |
[A thiamine antagonist due to its inhibition of thiamine pyrophosphorylation. It is used to produce thiamine deficiency.
] |
|
Pyrithioxin
|
D011746 |
[A neurotropic agent which reduces permeability of blood-brain barrier to phosphate. It has no vitamin B6 activity.
] |
|
Pyrobaculum
|
D041543 |
[A genus of rod-shaped, almost rectangular ARCHAEA, in the family THERMOPROTEACEAE. Organisms are facultatively aerobic or strictly anaerobic, grow on various organic substrates, and are found in continental solfataras.
] |
|
Pyrococcus
|
D019711 |
[A genus of strictly anaerobic ultrathermophilic archaea, in the family THERMOCOCCACEAE, occurring in heated seawaters. They exhibit heterotrophic growth at an optimum temperature of 100 degrees C.
] |
|
Pyrococcus abyssi
|
D043903 |
[A species of gram-negative hyperthermophilic ARCHAEA found in deep ocean hydrothermal vents. It is an obligate anaerobe and obligate chemoorganotroph.
] |
|
Pyrococcus furiosus
|
D020027 |
[A species of strictly anaerobic, hyperthermophilic archaea which lives in geothermally-heated marine sediments. It exhibits heterotropic growth by fermentation or sulfur respiration.
] |
|
Pyrococcus horikoshii
|
D043902 |
[Anaerobic hyperthermophilic species of ARCHAEA, isolated from hydrothermal fluid samples. It is obligately heterotrophic with coccoid cells that require TRYPTOPHAN for growth.
] |
|
Pyrodictiaceae
|
D041523 |
[A family of archaea, in the order DESULFUROCOCCALES consisting of anaerobic coccoid to disc-shaped cells. They grow either chemolithoautotrophically or by FERMENTATION. Three genera are recognized: Pyrodictium, Hyperthermus, and Pyrolobus.
] |
|
Pyrogallol
|
D011748 |
[A trihydroxybenzene or dihydroxy phenol that can be prepared by heating GALLIC ACID.
] |
|
Pyrogens
|
D011749 |
[Substances capable of increasing BODY TEMPERATURE and cause FEVER and may be used for FEVER THERAPY. They may be of microbial origin, often POLYSACCHARIDES, and may contaminate distilled water.
] |
|
Pyroglobulins
|
D011750 |
[Atypical gamma immunoglobulins characterized by their irreversible heat denaturation at 56-degrees C. Pyroprecipitation is inhibited at pH below 3 and above 9. The presence of pyroglobulins in the serum is the cause of pyroglobulinemia. They are frequently present in multiple myeloma and the pyroglobulin precipitate binds complement, reacts with rheumatoid factor, produces passive cutaneous anaphylaxis, generalized passive anaphylaxis and passive Arthus-type phenomena.
] |
|
Pyroglutamate Hydrolase
|
D011752 |
[Hydrolyzes pyroglutamic acid in the presence of ATP to glutamate plus ADP and inorganic phosphate. Deficiency leads to pyroglutamic acidurea.
] |
|
Pyroglutamyl-Peptidase I
|
D011751 |
[An enzyme that catalyzes the release of a N-terminal pyroglutamyl group from a polypeptide provided the next residue is not proline. It is inhibited by thiol-blocking reagents and occurs in mammalian tissues, microorganisms, and plants. (From Enzyme Nomenclature, 1992) EC 3.4.19.3.
] |
|
Pyroglyphidae
|
D039981 |
[Family of house dust mites, in the superfamily Analgoidea, order Astigmata. They include the genera Dermatophagoides and Euroglyphus.
] |
|
Pyrola
|
D031828 |
[A plant genus of the family PYROLACEAE. The common name of wintergreen is more often used for GAULTHERIA.
] |
|
Pyrolaceae
|
D031827 |
[A plant family of the order Ericales, subclass Dilleniidae, class Magnoliopsida.
] |
